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Immunological Aspects of Reproduction and Fertility Control pp 3–31Cite as

Immunological Relationships between Mother and Fetus during Pregnancy

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Abstract

Placentation is defined as ‘any intimate apposition or fusion of the fetal organs to the maternal or paternal tissues for physiological exchange’1. It is widespread amongst the invertebrates and vertebrates, having arisen independently in those phyla which exhibit viviparity, and has probably evolved each time from external fertilization to internal fertilization and oviparity, through ovoviviparity to viviparity.

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References

  1. Mossman, A. W. (1937). Comparative morphogenesis of the fetal membrane and accessory uterine structures. Contrib. Embryol. Carneg. Inst. Wash., 26, 129

    Google Scholar 

  2. Barrington, E. J. W. (1964). Hormones and Evolution, p. 34 ( London: English and Universities Press )

    Google Scholar 

  3. Medawar, P. B. (1953). Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symp. Soc. Exp. Biol., 7, 320

    Google Scholar 

  4. Kaye, M. D. (1971). The evolution of placentation. Aust. N.Z. J. Obstet. Gynaecol., 11, 197

    PubMed  CAS  Google Scholar 

  5. Hagan, H. R. (1951). Embryology of the Viviparous Insects, p. 261 ( New York: Ronald Press Co. )

    Google Scholar 

  6. Brewin, B. I. (1956). The growth and development of a viviparous compound ascidian Hypsistozoa fasmeriana. Q. J. Microsc. Sci., 97, 435

    Google Scholar 

  7. Sutton, M. F. (1960). The sexual development of the Salpa fusiformis. J. Embryol. Exp. Morphol., 8, 268

    Google Scholar 

  8. Anderson, D. T. and Manton, S. M. (1972). Studies on the onychophora. VIII. The relationship between the embryos and the oviduct in the viviparous onychopherans Epiperipatus trinidadensis and Macroperipatus torquatus from Trinidad. Philos. Trans. R. Soc. Lond. B. (Biol. Sci.),264, 161

    Google Scholar 

  9. Tartar, V. (1970). Transplantation in protozoa. Transplant. Proc., 2, 183

    PubMed  CAS  Google Scholar 

  10. Hildemann, W. H., Johnson, I. S. and Jokiol, P. L. (1979) Immunocompetence in the lowest metazoan Phylum: transplantation immunity in sponges. Science, 204, 420

    PubMed  CAS  Google Scholar 

  11. Hildemann, W. H. (1979). Immunocompetence and allogeneic polymorphism among invertebrates. Transplantation, 27, 1

    PubMed  CAS  Google Scholar 

  12. Jenkin, C. R. (1976). In Marchalonis, J. J. (ed.), Comparative Immunology, p. 80. ( Oxford: Blackwell Scientific Publications )

    Google Scholar 

  13. Marchalonis, J. J. (1977). Immunity in Evolution, p. 43. ( Massachusetts: Harvard University Press )

    Google Scholar 

  14. Hildemann, W. H. (1970). Transplantation immunity in fishes Agnatha, Chondrichthyes and Osteichthyes. Transplant. Proc., 2, 53

    Google Scholar 

  15. Kaye, M. D., Jones, W. R. and Anderson, D. T. (1972) Immunology and placentation in viviparous invertebrates. J. Reprod. Fertil., 31, 335

    PubMed  CAS  Google Scholar 

  16. Aristotle. In Peck, A. L. (ed.) (1970). Historia Animalium HA565B. The Loeb Classical library. ( London: Heinemann )

    Google Scholar 

  17. Hogarth, P. J. (1968). Immunological aspects of feto-maternal relations in lower vertebrates. J. Reprod. Fertil. (Suppl. 3 ), 15

    Google Scholar 

  18. Weekes, H. C. (1933). On the distribution, habitat and reproductive habits of certain European and Australian snakes and lizards with particular regard to their adaptation to viviparity. Proc. Linn. Soc. NSW, 58, 271

    Google Scholar 

  19. Yaron, Z. (1977). In Calaby, J. H. and Tyndale-Biscoe, C. H. (eds.) Reproduction and Evolution, p. 271. (Australian Academy of Sciences)

    Google Scholar 

  20. Amoroso, E. C. (1964). In Parkes, A. S. (ed.) Marshall’s Physiology of Reproduction, Vol. 2, p. 127. ( London: Longmans )

    Google Scholar 

  21. Amoroso, E. C. (1968). The evolution of viviparity. Proc. R. Soc. Med., 61, 1188

    PubMed  CAS  Google Scholar 

  22. Hughes, R. L. (1977). In Calaby, J. H. and Tyndale-Biscoe, C. H. (eds.) Reproduction and Evolution, p. 281. (Australian Academy of Sciences)

    Google Scholar 

  23. Padykula, H. A. and Taylor, J. M. (1977). In Calaby, J. H. and Tyndale-Biscoe, C. H. (eds.) Reproduction and Evolution, p. 303. (Australian Academy of Sciences)

    Google Scholar 

  24. Steven, D. (1975). Comparative Placentation, p. 58. ( London: Academic Press )

    Google Scholar 

  25. Hughes, R. L. (1974). Morphological studies on implantation in marsupials. J. Reprod. Fertil., 39, 173

    PubMed  CAS  Google Scholar 

  26. Weekes, H. C. (1927). Placentation and other phenomena in the scincid lizard Lygosoma quoyi. Proc. Linn. Soc. NSW, 55, 499

    Google Scholar 

  27. Weekes, H. C. (1935). A review of placentation among reptiles with particular regard to the function and evolution of the placenta. Proc. Zool. Soc. Lond., 625

    Google Scholar 

  28. Sharman, G. B. (1970). Reproductive physiology of marsupials. Science, 167, 1221

    PubMed  CAS  Google Scholar 

  29. Lillegraven, J. A. (1975). Biological considerations of the marsupial-placental dichotomy. Evolution, 29, 707

    Google Scholar 

  30. Zinkernagel, R. M., Callahan, G. N., Klein, J. and Dennert, G. (1978). Cytotoxic T cells learn specificity for self H-2 during differentiation in the thymus. Nature (London), 271, 251

    CAS  Google Scholar 

  31. Borysenko, M. (1979). Evolution of lymphocytes and vertebrate alloimmune reactivity. Transplant. Proc., 11, 1123

    PubMed  CAS  Google Scholar 

  32. Toivanen, A. (1979). Interactions of leucocytes in phylogenetic perspective. Transplant. Proc., 11, 1131

    PubMed  CAS  Google Scholar 

  33. Robertson, M. (1979). Recognition, restriction and immunity. Nature (London), 280, 192

    CAS  Google Scholar 

  34. Erickson, R. P. (1977). In Edidin, M. and Johnson, M. H. (eds.) Immunobiology of Gametes, p. 85. (Cambridge University Press)

    Google Scholar 

  35. Marcus, G. J. and Shelesnyak, M. C. (1968). Studies on the mechanism of nidation. Acta Endocrinol., 57 (Suppl. 123), 136

    PubMed  CAS  Google Scholar 

  36. Beer, A. E. and Billingham, R. E. (1974). Host responses to intrauterine tissue, cellular and fetal allografts. J. Reprod. Fertil. (Suppl. 21 ), 59

    Google Scholar 

  37. Overstreet, J. W. and Cooper, G. W. (1979). Effect of ovulation and sperm motility on the migration of rabbit spermatozoa to the site of fertilization. J. Reprod. Fertil., 55, 53

    PubMed  CAS  Google Scholar 

  38. Cohen, J. and Werrett, D. J. (1975). Antibodies and sperm survival in the female genital tract of the mouse and rabbit. J. Reprod. Fertil., 42, 301

    PubMed  CAS  Google Scholar 

  39. Cohen, J. and McNaughton, D. C. (1974). The probable selection of a small population by the genital tract of the female rabbit. J. Reprod. Fertil., 39, 297

    PubMed  CAS  Google Scholar 

  40. Overstreet, J. W. and Katz, D. F. (1977). In Johnson, M. H. (ed.) Development of Mammals, Vol. 2, p. 31. ( Amsterdam: North Holland Publ. Co. )

    Google Scholar 

  41. Thibault, C. (1973). Sperm transport and storage in vertebrates. J. Reprod. Fertil., (Suppl. 18 ), 39

    CAS  Google Scholar 

  42. Racey, P. A. (1975). In Duckett, J. G. and Racey, P. A. (eds.) Biology of the male Gamete. Biol. J. Linn. Soc., 7 ( Suppl. I), 385

    Google Scholar 

  43. Dobzhansky, T. (1977). In Dobzhansky, T., Ayala, F. J., Stebbins, G. L. and Valentine, J. W. (eds.) Evolution, p. 171. ( San Francisco: W. H. Freeman )

    Google Scholar 

  44. Bolwell, G. P., Callow, J. A., Callow, M. E. and Evans, L. V. (1977). Cross fertilization in fucoid seaweeds. Nature (London), 268, 626

    Google Scholar 

  45. Metz, C. B. (1978). Sperm and egg receptors involved in fertilization. Curr. Top. Devel. Biol., 12, 107

    CAS  Google Scholar 

  46. Miller, R. L. (1977). In Adiyodi, K. G. and Adiyodi, P. G. (eds.) Advances in Invertebrate Reproduction, 1, 99. ( India: Peralam-Kenoth Kariueller )

    Google Scholar 

  47. Franklin, L. E. (1970). Fertilization and the role of the acrosomal region in non-mammals. Biol. Reprod. (Suppl. 2 ), 159

    PubMed  Google Scholar 

  48. Yanagimachi, R. (1978). Sperm-egg associations in mammals. Curr. Top. Devel. Biol., 12, 83

    CAS  Google Scholar 

  49. Vacquier, V. D. and Moy, G. W. (1977). Isolation of bindin: the protein responsible for adhesion of sperm to sea urchin eggs. Proc. Natl. Acad. Sci.. 74, 2456

    PubMed  CAS  Google Scholar 

  50. Epel, D. (1978). Mechanisms of activation of sperm and eggs during fertilization of sea urchin gametes. Curr. Top. Devel. Biol., 12, 185

    CAS  Google Scholar 

  51. Austin, C. R. (1978). Patterns in metozoan fertilization. Curr. Top. Devel. Biol., 12, 1

    CAS  Google Scholar 

  52. Miyake, A. (1978). Cell communication, cell union and initiation of meiosîs in ciliate conjugation. Curr. Top. Devel. Biol., 12, 37

    CAS  Google Scholar 

  53. Kaye, M. D. (1973). Immunological studies in mammalian placentation. PhD Thesis, Sydney University

    Google Scholar 

  54. Monroy, A. and Rosati, F. (1979). The evolution of the cell-cell recognition system. Nature (London), 278, 165

    CAS  Google Scholar 

  55. Halbert, S. A., Tam, P. Y. and Blandau, R. J. (1976). Egg transport in the rabbit oviduct: the roles of cilia and muscle. Science, 191, 1052

    PubMed  CAS  Google Scholar 

  56. Eddy, C. A., Flores, J. J., Archer, D. R. and Paverstein, C. J. (1979). The role of cilia in fertility: an evaluation by selective microsurgical modification of the rabbit oviduct. Am. J. Obstet. Gynecol., 132, 814

    Google Scholar 

  57. Finn, C. A. (1977). In Wynn, R. M. (ed.) Biology of the Uterus, p. 245. ( New York: Plenum Press )

    Google Scholar 

  58. Freese, V. E., Ormans, S. and Pavlos, G. (1973). An autoradiographic investigation of epithelium egg interaction in the mouse oviduct. Am. J. Obstet. Gynecol., 117, 364

    PubMed  CAS  Google Scholar 

  59. Ledford, B. E., Rankin, J. C., Froble, F. L., Serra, M. J., Markwald, R. R. and Baggett, B. (1978). The decidual cell reaction in the mouse uterus: DNA synthesis and autoradiographic analysis of responsive cells. Biol. Reprod., 18, 506

    PubMed  CAS  Google Scholar 

  60. Ansell, J. D., Barlow, P. W. and McLaren, A. (1974). Binucleate and polyploid cells in the decidua of the mouse. J. Embryol. Exp. Morphol., 31, 223

    PubMed  CAS  Google Scholar 

  61. Chapman, V. M., Ansel!, J. D. and McLaren, A. (1972). Trophoblast giant cell differentiation in the mouse: expression of glucose phosphate isomerase variants in transferred chimeric embryos. Develop. Biol., 29, 48

    PubMed  CAS  Google Scholar 

  62. Heap, R. B., Flint, A. P. F., Gadsby, J. E. and Rice, C. (1979). Hormones, the early embryo and the uterine environment. J. Reprod. Fertil., 55, 267

    PubMed  CAS  Google Scholar 

  63. Johnson, M. H. (1979). Intrinsic and extrinsic factors in pre-implantation development. J. Reprod. Fertil., 55, 255

    PubMed  CAS  Google Scholar 

  64. Gardner, R. (1975). In Edwards, R. G., Howe, C. W. S. and Johnson, M. H. (eds.) Immunobiology of Trophoblast, p. 43. (Cambridge University Press)

    Google Scholar 

  65. Hill, J. P. (1897). The placentation of perameles. Q. J. Microsc. Sci., 40, 385 and 43, 1

    Google Scholar 

  66. Flynn, T. (1923). Placentation of parameles. Q. J. Microsc. Sci., 67, 123

    Google Scholar 

  67. Hill, J. P. (1900). On the fetal membranes, placentation and parturition of the native cat. Anat. Anz., 18, 364

    Google Scholar 

  68. Larsen, J. F. (1961). Electron microscopy of the implantation site in the rabbit. Ant. J. Anat., 109, 319

    CAS  Google Scholar 

  69. Schlafke, S. and Enders, A. C. (1975). Cellular basis of interaction between trophoblast and uterus at implantation. Biol. Reprod., 12, 41

    PubMed  CAS  Google Scholar 

  70. McLennan, J. G. (1974). Ultrastructural studies of early nidation in pregnancy and pseudopregnancy. Am. J. Obstet. Gynecol., 120, 319

    PubMed  CAS  Google Scholar 

  71. Avery, G. B. and Hunt, C. V. (1969). The differentiation of trophoblast giant cells in the mouse studied in kidney capsule grafts. Transplant. Proc., 1, 61

    PubMed  CAS  Google Scholar 

  72. Galassi, L. (1967). Reutilization of maternal nuclear material by embryonic and trophoblastic cells in the rat for the synthesis of DNA. J. Histochem. Cytochem., 15, 573

    PubMed  CAS  Google Scholar 

  73. Ledoux, L. and Charles, P. (1967). Uptake of exogenous DNA by mouse embryos. Exp. Cell. Res., 45, 498

    PubMed  CAS  Google Scholar 

  74. Kaye, M. D. (1977). An autoradiographic study of the implantation of transferred mouse blastocysts. Aust. J. Biol. Sci., 30, 577

    PubMed  CAS  Google Scholar 

  75. Daniel, J. C. and Chilton, B. S. (1978). In Johnson, M. H. (ed.) Development in Mammals, Vol. 3, p. 131. ( Amsterdam: North Holland Publ. Co. )

    Google Scholar 

  76. Kantor, J. A., Lee, Y. H., Chirikjian, J. G. and Fellow, W. F. (1979). DNA polymerase with characteristics of reverse transcriptase purified from human milk. Science, 204, 511

    PubMed  CAS  Google Scholar 

  77. Harris, H., Sidebottom, E., Grace, D. M. and Bramwell, M. E. (1969). The expression of genetic information: a study with hybrid animal cells. J. Cell. Sci.. 4, 499

    PubMed  CAS  Google Scholar 

  78. Croce, C., M. and Koprowski, H. (1978). The genetics of human cancer. Sci. Am., 238, 117

    Google Scholar 

  79. Marx, J. L. (1977). Gene transfer in mammalian cells mediated by chromosomes. Science, 197, 146

    PubMed  CAS  Google Scholar 

  80. Little, C. C. (1924). The genetics of tissue transplantation in mammals. J. Cancer Res., 8, 75

    Google Scholar 

  81. Edidin, M. (1976). Embryogenesis in mammals. CIBA Foundation Symp., 40 (new series), p. 177

    Google Scholar 

  82. Hakansson, S., Heyner, S., Sundquist, K. and Bergstrom, S. (1975). The presence of paternal H-2 antigens on hybrid mouse blastocysts during experimental delay of implantation and the disappearance of the antigens after onset of implantation. Int. J. Fertil., 20, 137

    PubMed  CAS  Google Scholar 

  83. Barrett, D. and Angelo, G. M. (1969). Maternal characteristics of hatching enzymes in hybrid sea urchin embryos. Exp. Cell. Res., 57, 159

    PubMed  CAS  Google Scholar 

  84. Wright, D. A. and Subtelny, S. (1969). The expression of genes controlling enzymes in the diploid and androgenetic haploid hybrid frog embryos. J. Cell. Biol., 43, 160a

    Google Scholar 

  85. Castro-Sierra, E. and Ohno, S. (1968). Allelic inhibition of the autosomally inherited gene locus for liver alcohol dehydrogenase in chicken-quail hybrids. Biochem. Genet., 1, 323

    PubMed  CAS  Google Scholar 

  86. Hitzeroth, H., Klose, J., Ohno, S. and Wolf, V. (1968). Asynchronous activation of parental alleles at the tissue specific gene loci observed on hybrid trout during early development. Biochem. Genet., 1, 287

    PubMed  CAS  Google Scholar 

  87. Chapman, V. M., Adler, D., Labarca, C. and Wudl, L. (1976). Embryogenesis in Mammals. Ciba Foundation Symp., 40 (new series), p. 115

    Google Scholar 

  88. Wudl, L. and Chapman, V. M. (1976). The expression of 13 glucuronidase during pre-implantation development of mouse embryos. Der. Biol. 48, 104

    CAS  Google Scholar 

  89. Muggleton-Harris, A. L. and Johnson, M. H. (1976). The nature and distribution of serologically detectable alloantigens on the pre-implantation mouse embryo. J. Embryol. Exp. Morphol., 35, 59

    PubMed  CAS  Google Scholar 

  90. Krco, C. J. and Goldberg, E. H. (1976). H-Y antigen: detection on eight cell mouse embryos. Science, 193, 1134

    PubMed  CAS  Google Scholar 

  91. Searle, R. F. and Jenkinson, E. J. (1978). Localization of trophoblast defined surface antigens during early mouse embryogenesis. J. Embryo!. Exp. Morphol., 43, 147

    CAS  Google Scholar 

  92. Carter, J. (1976). Expression of maternal and paternal antigens on trophoblast. Nature (London), 262, 292

    CAS  Google Scholar 

  93. Sellens, M. H. (1977). Antigen expression on early mouse trophoblast. Nature (London), 269, 60

    CAS  Google Scholar 

  94. Webb, C. B., Gall, W. E. and Edelman, G. M. (1977). Synthesis and distribution of H-2 antigens in pre-implantation mouse embryos. J. Exp. Med., 146, 923

    PubMed  CAS  Google Scholar 

  95. Parr, E. L. and Moore, H. A. (1977). In Calaby, J. H. and Tyndale-Biscoe, C. H. (eds.) Reproduction und Evolution, p. 363. (Australian Academy of Sciences)

    Google Scholar 

  96. Simmons, R. L. and Russell, P. S. (1966). The histocompatibility antigens of fertilized mouse eggs and trophoblast. Ann. N.Y. Acad. Sci., 129, 35

    Google Scholar 

  97. James, D. A. (1960). Antigenicity of the blastocyst masked by the zona pellucida. Transplantation, 8, 846

    Google Scholar 

  98. Heyner, S., Brinster, R. L. and Palm, J. (1969). Effect of isoantibody on pre-implantation mouse embryos. Nature (London), 222, 783

    CAS  Google Scholar 

  99. Moskalewski, S. and Koprowski, H. (1972). Presence of egg antigen in immature oocytes and pre-implantation embryos. Nature (London), 237, 167

    CAS  Google Scholar 

  100. Kirby, D. R. S. (1969). On the immunological function of the zona pellucida. Fertil. Sieril., 20, 933

    CAS  Google Scholar 

  101. Dickmann, Z. and De Feo, V. J. (1967). The rat blastocyst during normal pregnancy and during delayed implantation, including an observation on the shedding of the zona pellucida. J. Reprod. Fertil.. 13, 3

    PubMed  CAS  Google Scholar 

  102. Short, R. V. and Hay, M. F. (1966). Comparative reproduction in mammals. Delayed implantation in the roe deer Capreolus capreolus. Symp. Zool. Soc. Loud., 15, 173

    Google Scholar 

  103. Lobel, B. L., Levy, E. and Shelesnyak, M. C. (1967). Studies on the mechanism of nidation. Acta Endocrinol. (Suppl. 123 ), 7

    Google Scholar 

  104. Hamilton, W. J. (1970). In Hubinont, P. O., Le Roy, F., Robyn, C. and Leleux, P. (eds.) Ovoimplantation, Human Gonadotropins and Prolactin, p. 149. ( New York: S. Karger )

    Google Scholar 

  105. Mulnard, J. G. (1970). In Hubinont, P. O., Le Roy, F., Robyn, C. and Leleux, P. (eds.) Ovoimplantation, Human Gonadotropins and Prolactin, p. 9. ( New York: S. Karger )

    Google Scholar 

  106. Grosser, O. (1927). Fruheutvvicklumg eihautbildung und placentation des menschen und der saugestierre. (Munchen: J. F. Bergmann, VIII U454S)

    Google Scholar 

  107. Enders, A. C. (1965). A comparative study of the fine structure of the trophoblast in several hemochorial placentae. Ani. J. Anat., 116, 29

    CAS  Google Scholar 

  108. Bardawil, W. A. and Toy, B. L. (1959). The natural history of choriocarcinoma. Problems of immunity and spontaneous regression. Ann. N.Y. Acad. Sci., 80, 197

    PubMed  CAS  Google Scholar 

  109. Kirby, D. R. S., Billington, W. D., Bradbury, S. and Goldstein, D. J. (1964). Antigen barrier of the mouse placenta. Nature (London), 204, 548

    CAS  Google Scholar 

  110. Kirby, D. R. S., Billington, W. D. and James, D. A. (1966). Transplantation of eggs to the kidney and uterus of immunised mice. Transplantation, 4, 713

    PubMed  CAS  Google Scholar 

  111. Simmons, R. L., Cruse, V. and McKay, D. G. (1967). The immunologic problem of pregnancy. II. Ultrastructure of isogenic and allogenic transplants. Am. J. Obstet. Gynecol., 97, 218

    PubMed  CAS  Google Scholar 

  112. Wynn, R. M. (1967). Comparative electron microscopy of the placental junctional zone. Obstet. Gynecol., 29, 644

    PubMed  CAS  Google Scholar 

  113. Martinek, J. J. (1970). Fibrinoid and the fetal maternal interface of the rat placenta. Anat. Rec., 166, 587

    PubMed  CAS  Google Scholar 

  114. Simmons, R. L. and Russell, P. S. (1966). The histocompatibility antigens of fertilized mouse eggs and trophoblast. Ann. N.Y. Acad. Sci., 129, 35

    Google Scholar 

  115. Currie, G. A., Van Doorninck, W. and Bagshawe, K. D. (1968). The effect of neuraminidase on the immunogenicity of early mouse trophoblast. Nature (London), 219, 191

    CAS  Google Scholar 

  116. Simmons, R. L., Lipschultz, M. L., Rios, A. and Ray, P. K. (1971). Failure of neuraminidase to unmask histocompatibility antigens on trophoblast. Nature (London), 231, 111

    CAS  Google Scholar 

  117. Jenkinson, E. J. and Billington, W. D. (1974). Differential susceptibility, of mouse trophoblast and embryonic tissue to immune cell lysis. Transplantation, 18, 286

    PubMed  CAS  Google Scholar 

  118. Edidin, M. (1972). In Kahan, B. D. and Reisfeld, R. A. (eds.) Transplantation Antigens, p. 75. ( New York: Academic Press )

    Google Scholar 

  119. Bagshawe, K. and Lawler, S. (1975). In Edwards, R. G., Howe, C. W. S. and Johnson, M. H. (eds.) Immunobiology of Trophoblast, p. 171. (Cambridge University Press)

    Google Scholar 

  120. Jenkinson, E. J. and Searle, R. F. (1979). Ia-antigen expression on the developing mouse embryo and placenta. J. Reprod. Immunol., 1, 3

    PubMed  CAS  Google Scholar 

  121. Koren, Z., Abrams, G. and Behrman, S. J. (1968). Antigenicity of mouse placental tissue. Am. J. Obstet. Gynecol., 102, 340

    PubMed  CAS  Google Scholar 

  122. Beer, A. E., Billingham, R. E. and Yang, S. L. (1972). Further evidence concerning the auto-antigenic status of the trophoblast. J. Exp. Med., 135, 1177

    PubMed  CAS  Google Scholar 

  123. Kirby, D. R. S. (1969). Antigenicity of mouse placental tissue. Am. J. Obstet. Gynecol., 105, 289

    PubMed  CAS  Google Scholar 

  124. Schlesinger, M. (1964). Serologic studies of embryonic and trophoblastic tissues of the mouse. J. Inununol., 93, 255

    CAS  Google Scholar 

  125. Carter, J. (1978). The expression of surface antigens on three trophoblastic tissues in the mouse. J. Reprod. Fertil., 54, 433

    PubMed  CAS  Google Scholar 

  126. Sellens, M. H., Jenkinson, E. J. and Billington, W. D. (1978). Major histocompatibility complex and non-major histocompatibility complex antigens on mouse ectoplacental cone and placental trophoblastic cells. Transplantation, 25, 173

    PubMed  CAS  Google Scholar 

  127. Loke, Y. W. (1978). Immunology and lmmunopathology of the Human Fetal and Maternal Interaction. ( Amsterdam: Elsevier/North Holland Biomedical Press )

    Google Scholar 

  128. Simmons, R. L. and Russell, P. S. (1967). Xenoantigens in mouse trophoblast. Transplantation, 5, 85

    Google Scholar 

  129. Dehem, A., Sobis, H. and Vandeputte, M. (1971). Effect of immunosuppression on the development of xenogenic trophoblast under the kidney capsule. Transplantation, 11, 578

    PubMed  CAS  Google Scholar 

  130. Dent, J., McGovern, P. T. and Hancock, J. L. (1971). Immunological implications of ultrastructural studies of goat sheep hybrid placentae. Nature (London), 231, 116

    CAS  Google Scholar 

  131. Poppa, G., Simmons, R. L., David, D. S. and Russell, P. S. (1964). The uterus as a recipient site for parathyroid homotransplantation. Transplantation, 2, 496

    PubMed  CAS  Google Scholar 

  132. Medawar, P. B. and Sparrow, E. M. (1956). The effects of adreno cortical hormones, adreno corticotrophic hormone and pregnancy on skin transplantation immunity in mice. J. Endocrinol., 14, 240

    PubMed  CAS  Google Scholar 

  133. Beer, A. E., Billingham, R. E. and Hoerr, R. A. (1971). Elicitation and expression of transplantation in the uterus. Transplant. Proc., 3, 609

    PubMed  CAS  Google Scholar 

  134. Lanman, J. T., Herod, L. and Fekrig, S. (1964). Homograft immunity in pregnancy: Survival rates in rabbits born of ova transplanted into sensitised mothers. J. Exp. Med., 119, 781

    PubMed  CAS  Google Scholar 

  135. Watnick, A. S. and Russo, R. A. (1968). Survival of skin homografts in uteri of pregnant and progesterone and estrogen treated rats. Proc. Soc. Exp. Biol. Med., 128, 1

    PubMed  CAS  Google Scholar 

  136. Kaye, M. D., Jones, W. R. and Ing, R. M. Y. (1974). An investigation of privilege in the pregnant rat uterus. J. Reprod. Fertil., 36, 467

    Google Scholar 

  137. Kirby, D. R. S. (1969). Adv. Biosc., 4, 255

    Google Scholar 

  138. Samuel, C. A. and Perry, J. S. (1972). The ultrastructure of pig trophoblast transplanted to an ectopic site in the uterine wall. J. Anat., 113, 139

    PubMed  CAS  Google Scholar 

  139. Galtsoff, P. S. and Galtsoff, E. (1953). Destruction, survival and disorganised growth of embryonic organs and tissues of Opsanus tau after homoplastic transplantation of whole embryos in the adult toad fish. Anat. Rec., 117, 601

    Google Scholar 

  140. Breyere, E. J. and Barrett, M. K. (1960). Prolonged survival of skin homografts in parous female mice. J. Natl. Cancer Inst., 25, 1405

    Google Scholar 

  141. Goodlin, R. C. and Herzenberg, L. A. (1964). Pregnancy induced haemagglutinins to paternal H-2 antigens in multiparous mice. Transplantation, 2, 357

    PubMed  CAS  Google Scholar 

  142. Hellstrom, K. E., Hellstrom, I. and Brown, J. (1969). Abrogation of cellular immunity to antigenically foreign mouse embryonic cells by a serum factor. Nature (London), 224, 914

    CAS  Google Scholar 

  143. Beer, A. E., Head, J. R., Smith, W. G. and Billingham, R. E. (1976). Some immunoregulatory aspects of pregnancy in rats. Transplant. Proc., 8, 267

    PubMed  CAS  Google Scholar 

  144. Chaouat, G., Voisin, G. A., Escalier, D. and Robert, P. (1979). Facilitation reaction (enhancing antibodies and suppressor cells) and rejection reaction (sensitised cells) from the mother to the paternal antigens of the conceptus. Clin. Exp. Inmunol., 35, 13

    CAS  Google Scholar 

  145. Wegmann, T. G., Waters, C. A., Drell, D. W. and Carlson, G. A. (1979). Pregnant mice are not primed but can be primed to fetal alloantigens. Proc. Natl. Acad. Sci., 76, 2410

    PubMed  CAS  Google Scholar 

  146. Kaye, M. D. (1973). Human lymphocyte responses during pregnancy. J. Reprod. Fertil., 32, 333

    PubMed  CAS  Google Scholar 

  147. Hawes, C. S., Kemp, A. S., Jones, W. R. and Need, J. A. Personal communication

    Google Scholar 

  148. Forster, P. M., McLean, J. M. and Gibbs, A. C. C. (1979). Lymphoid response to pregnancy and pseudopregnancy in the rat. J. Anat., 128, 837

    PubMed  CAS  Google Scholar 

  149. Gusdon, J. P. (1976). In Scott, J. S. and Jones, W. R. (eds.) Immunology of Human Reproduction, p. 103. ( London: Academic Press )

    Google Scholar 

  150. Rocklin, R. E., Kitzmiller, J. L. and Kaye, M. D. (1979). Immunobiology of the maternal fetal relationship. Ann. Rev. Med., 30, 375

    PubMed  CAS  Google Scholar 

  151. Walker, K. Z. and Tyndale-Biscoe, C. H. (1978). Immunological aspects of gestation in the Tammar wallaby Macropus eugenii. Aust. J. Biol. Sci., 31, 173

    CAS  Google Scholar 

  152. Heslop, R. W., Kohn, P. L. and Sparrow, E. M. (1954). The effect of pregnancy on the survival of skin allografts in rabbits. J. Endocrinol., 10, 325

    PubMed  CAS  Google Scholar 

  153. Billingham, R. E. (1971). Transplantation biology of mammalian gestation. Am. J. Obstet. Gynecol., 111, 469

    PubMed  CAS  Google Scholar 

  154. Zipper, J., Ferrando, G., Saez, G. and Tehernitchin, A. (1966). Intra uterine grafting in rats of autologous and homologous adult rat skin. Am. J. Obstet. Gynecol., 94, 1056

    PubMed  CAS  Google Scholar 

  155. Nelson, J. H., Hall, J. E., Manuel-Limson, G., Friedberg, H. and O’Brien, F. J. (1967). Effect of pregnancy on the thymolymphatic system. I. Changes in the intact rat after exogenous HCG, estrogen and progesterone administration. Am. J. Obstet. Gynecol., 98, 895

    PubMed  Google Scholar 

  156. Amoroso, E. C. and Perry, J. S. (1975). The existence during gestation of an immunological buffer zone at the interface between fetal and maternal tissues. Phil. Trans. R. Soc. Land. Ser. B., 271, 343

    CAS  Google Scholar 

  157. Kaye, M. D. and Jones, W. R. (1973). In vitro activity of sensitised maternal lymphocytes to paternal and embryonic tissues in the rat. IRCS (73–12), 3.10.37

    Google Scholar 

  158. Berg, M., Burton, R. C., Smith, J. A., Luckenbach, G. A., Decker, J. and Mitchell, G. F. (1978). Effects of placental tissue on immunological responses. Clin. Exp. Inununol., 34, 441

    Google Scholar 

  159. Alexander, P. (1974). Escape from immuno destruction by the host through shedding of surface antigens. Is this a characteristic shared by malignant and embryonic cells? Cancer Res., 34, 2077

    PubMed  CAS  Google Scholar 

  160. Sander, T., Sonea, S. and Mead, A. Z. (1975). The possible role of steroids in evolution. Am. Zool., 15 (Suppl. 1), 227

    Google Scholar 

  161. Licht, P., Papkoff, H., Farmer, S. W., Muller, C. H., Tsuitt, W. and Crews, D. (1977). Evolution of gonadotropins, structure and function. Recent Prog. Horm. Res., 33, 169

    Google Scholar 

  162. Channing, C. P., Stone, S. L., Sakai, C. N., Haour, F. and Saxena, B. B. (1978). A stimulatory effect of the fluid from the pre-implantation rabbit blastocysts upon luteinization of monkey granulosa cell cultures. J. Reprod. Fertil., 54, 215

    PubMed  CAS  Google Scholar 

  163. Tyndale-Biscoe, C. H., Hearn, J. P. and Renfree, M. B. (1974). Control of reproduction in Macropodid Marsupials. J. Endocrinol., 63, 589

    PubMed  CAS  Google Scholar 

  164. Renfree, M. B. (1977). In Calaby, J. H. and Tyndale-Biscoe, C. H. (eds.) Reproduction and Evolution, p. 325. (Australian Academy of Sciences)

    Google Scholar 

  165. Simmons, R. L., Price, A. L. and Oserkis, A. J. (1968). The immunologic problems of pregnancy. V. The effect of estrogen and progesterone on allograft survival. Am. J. Obstet. Gynecol., 100, 908

    PubMed  CAS  Google Scholar 

  166. Waltman, S. R., Burde, R. M. and Barrios, J. (1971). Prevention of corneal homograft rejection by estrogens. Transplantation, 11, 194

    PubMed  CAS  Google Scholar 

  167. Hulka, J. F., Mohr, K. and Liberman, M. W. (1965). Effect of synthetic progestational agents on allograft rejection and circulating antibody production. Endocrinology, 77, 897

    PubMed  CAS  Google Scholar 

  168. Munroe, J. S. (1971). Progesteroids as immunosuppressive agents. J. Reticuloendoth. Soc., 9, 361

    CAS  Google Scholar 

  169. Siiteri, P. K., Febres, F., Clemens, L. E., Chang, R. J., Gondos, B. and Stites, D. (1977). Progesterone and maintenance of pregnancy. Is progesterone Nature’s immunosuppressant. Ann. N.Y. Acad. Sci., 286, 384

    PubMed  CAS  Google Scholar 

  170. Beer. A. E. and Billingham, R. E. (1979). Maternal Recognition of Pregnancy. Ciba Foundation Symp., 64 (new series), p. 293

    Google Scholar 

  171. Padykula, H. A. and Tansey, T. R. (1979). The occurrence of uterine stromal and intra epithelial monocytes and heterophils during normal late pregnancy in the rat. Anat. Rec., 193, 329

    PubMed  CAS  Google Scholar 

  172. Billingham, R. E., Krohn, P. L. and Medawar, P. B. (1951). Effect of locally applied cortisone acetate on survival of skin allografts in rabbits. Br. Med. J., 2, 1049

    PubMed  CAS  Google Scholar 

  173. Pavia, C., Siiteri, P. K., Perlman, J. D. and Stites, D. P. (1979). Suppression of immune allogeneic cell interactions by sex hormones. J. Reprod. Immunol., 1, 33

    PubMed  CAS  Google Scholar 

  174. Younger, J. B., St. Pierre, R. L. and Zmijewski, C. M. (1969). Effect of human chorionic gonadotrophin on antibody production. Ani. J. Obstet. Gynecol.,105, 9

    Google Scholar 

  175. Kaye, M. D. and Jones, W. R. (1971). Effect of human chorionic gonadotrophin on in vitro lymphocyte transformation. Am. J. Obstet. Gynecol., 109, 1029

    PubMed  CAS  Google Scholar 

  176. Contractor, S. F. and Davies, H. (1973). Effect of human chorionic somatomammotrophin and hCG on phytohemagglutinin induced lymphocyte transformation. Nature (London), 243, 284

    CAS  Google Scholar 

  177. Caldwell, J. L., Stites, D. P. and Fudenberg, H. H. (1975). Human chorionic gonadotrophin. Effects of crude and purified preparations on lymphocyte responses to phytohaemagglutinin and allogeneic stimulation. J. Immunol., 115, 1249

    PubMed  CAS  Google Scholar 

  178. Morse, J. H., Stearn, C., Arden, J., Agosto, G. M. and Canfield, R. E. (1976). The effects of crude and purified human gonadotropin on in vitro stimulated human lymphocyte cultures. Cell. Immunol., 25, 178

    PubMed  CAS  Google Scholar 

  179. Kaye, M. D., Jones, W. R., Ing, R. M. Y. and Markham, R. (1971). Effect of human chorionic gonadotrophin on intrauterine skin allograft survival in rats. Am. J. Obstet. Gynecol., 110, 640

    PubMed  CAS  Google Scholar 

  180. Kaye, M. D., Jones, W. R. and Ing, R. M. Y. (1973). Effect of human chorionic gonadotrophin on intrauterine skin graft survival in F-1 hybrid rats. Am. J. Obstet. Gynecol., 116, 39

    PubMed  CAS  Google Scholar 

  181. Borland, R., Loke, Y. W. and Wilson, D. (1975). In Edwards, R. G., Howe, C. W. S. and Johnson, M. H. (eds.) Immunobiology of Trophoblast, p. 157. (Cambridge University Press)

    Google Scholar 

  182. Allen, W. R. (1975). In Edwards, R. G., Howe, C. W. S. and Johnson, M. H. (eds.) Immunobiology of Trophoblast, p. 217. (Cambridge University Press)

    Google Scholar 

  183. Ayoub, J. and Kasakura, S. (1971). In vitro response of fetal lymphocytes to PHA and a plasma factor which suppresses the PHA response of adult lymphocytes. Clin. Exp. Immunol., 8, 427

    PubMed  CAS  Google Scholar 

  184. Murgita, R. A. and Tomasi, T. B. (1975). Suppression of the immune response by alpha feto protein. I. Primary and secondary response. J. Exp. Med., 141, 269

    PubMed  CAS  Google Scholar 

  185. Littman, B. H., Alpert, E. and Rocklin, R. E. (1977). Effect of purified alpha feto protein on in vitro assays of cell mediated immunity. Cell. Immunol., 30, 35

    PubMed  CAS  Google Scholar 

  186. Bernard, O., Ripoche, M. A. and Bennett, D. (1977). Distribution of maternal immunoglobulins in the mouse uterus and embryo in the days after implantation. J. Exp. Med., 145, 58

    PubMed  CAS  Google Scholar 

  187. Lanman, J. T. and Herod, L. (1965). Homograft immunity in pregnancy: The placental transfer of cytotoxic antibodies in rabbits. J. Exp. Med., 122, 579

    PubMed  CAS  Google Scholar 

  188. Brambell, F. W. R. (1970). The Transmission of Passive Immunity from Mother to Young. ( Amsterdam: North Holland Publ. Co. )

    Google Scholar 

  189. Barnes, R. D. and Tuffrey, M. (1971). Maternal cells in the newborn. Adv. Biosc., 6, 457

    Google Scholar 

  190. Beer, A. E. and Billingham, R. E. (1973). Maternally acquired runt disease. Science, 179, 240

    PubMed  CAS  Google Scholar 

  191. Billington, W. R. (1976). In Scott, J. S. and Jones, W. R. (eds.) Immunology of Human Reproduction, p. 93. ( London: Academic Press )

    Google Scholar 

  192. Head, J. R., Beer, A. E. and Billingham, R. E. (1977). Significance of the cellular component of the maternal immunologic endowment in milk. Transplant. Proc., 9, 1465

    PubMed  CAS  Google Scholar 

  193. Silvers, W. K. and Poole, T. W. (1975). The influence of foster nursing on the survival and immunologic competence of mice and rats. J. Immunol., 115, 1117

    PubMed  CAS  Google Scholar 

  194. Trentin, J. J., Gallagher, M. T. and Priest, E. L. (1977). Failure of functional transfer of maternal lymphocytes to FI hybrid mice. Transplant. Proc., 9, 1473

    PubMed  CAS  Google Scholar 

  195. Kreidl, A. and Mandl, L. (1904). Uber den mebergang der immonhamolysine non der frucht auf die muher. Wein Klin Weschscht., 17, 611

    Google Scholar 

  196. Schinkel, P. G. and Ferguson, K. A. (1953). Skin transplantation in the fetal lamb. Aust. J. Biol. Sci., 6, 533

    Google Scholar 

  197. Owen, J. J., Cooper, M. D. and Ralt, M. C. (1974). In vitro generation of B lymphocytes in mouse fetal liver, a mammalian bursa equivalent. Nature (London), 249, 361

    CAS  Google Scholar 

  198. Silverstein, A. M. (1977). In Cooper, M. C. and Dayton, D. (eds.) Development of Host Defences, p. I. ( New York: Rowen Press )

    Google Scholar 

  199. Miller, J. F. A. P. (1961). Immunological function of the thymus. Lancet, 2, 748

    PubMed  CAS  Google Scholar 

  200. Solomon, J. B. (1971). Fetal and Neonatal Immunology, p. 234. ( Amsterdam: North Holland Publ. Co. )

    Google Scholar 

  201. Osoba, D. (1965). Immune reactivity in mice thymectomised soon after birth: normal response after pregnancy. Science, 147, 298

    Google Scholar 

  202. Clancy, J. (1978). Failure of pregnancy to restore immune competence in neonatally thymectomised rats. Transplantation, 26, 454

    PubMed  Google Scholar 

  203. Billington, W. D. (1964). Influence of immunological dissimilarity of mother and fetus on size of placenta in mice. Nature (London), 202, 317

    CAS  Google Scholar 

  204. McLaren, A. (1965). Genetic and environmental effects on fetal and placental growth in mice. J. Reprod. Fertil., 9, 79

    PubMed  CAS  Google Scholar 

  205. James, D. A. (1967). Some effects of immunological factors on gestation in mice. J. Reprod. Fertil., 14, 265

    PubMed  CAS  Google Scholar 

  206. Beer, A. E. and Billingham, R. E. (1977). Histocompatibility gene polymorphisms and maternal fetal interaction. Transplant. Proc., 9, 1393

    PubMed  CAS  Google Scholar 

  207. Clarke, B. C. and Kirby, D. R. S. (1966). Maintenance of histocompatibility polymorphisms. Nature (London), 211, 999

    CAS  Google Scholar 

  208. McLaren, A. (1975). In Edwards, R. G., Howe, C. W. E. and Johnson, M. H. (eds.) Immunobiology of Trophoblast, p. 255. (Cambridge University Press)

    Google Scholar 

  209. Hetherington, C. M. (1978). Absence of effect of maternal immunization to paternal antigens on placental weight, fetal weight and litter size in the mouse. J. Reprod. Fertil., 53, 81

    PubMed  CAS  Google Scholar 

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Kaye, M. (1980). Immunological Relationships between Mother and Fetus during Pregnancy. In: Hearn, J.P. (eds) Immunological Aspects of Reproduction and Fertility Control. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8039-9_1

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