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The Endometrium pp 25–42Cite as

Uterine Cell Biology and Phylogenetic Considerations: An Interpretation

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Abstract

The strong evolutionary imprint on mammalian reproductive systems creates an impressive barrier to interpretation of uterine cellular differentiation among different species. Especially during placental involvement, the uterus displays striking species variation which is considerably greater than occurs in other organs (e.g., liver, kidney, lung). During implantation, in most orders of mammals the uterine mucosa is eroded to varying degree during the formation of several principal types of chorio-allantoie placental associations characterized by differences in the number and types of cellular and tissue layers intervening between the maternal (uterine) and the fetal (allantoic) bloodstreams (Mossman, 1937; Amoroso, 1952; Enders, 1965; Steven, 1975). In rodents, rabbits, Old World monkeys, and human beings, the uterine luminal epithelium, stroma, and microvasculature are progressively destroyed as the formation of the hemochorial placenta places the maternal blood into direct contact with the fetal trophoblast. Ultrastructural analysis has reduced Grosser’s original classification of the chorioallantoic placental barriers into three major categories: (1) epitheliochorial (Artiodactyla, Perissodactyla, Cetacea, Lemuroidae), (2) endotheliochorial (most Carnivora, Pinnipedia), and hemochorial (Insectivora, Rodentia, Lagomorpha, Sirenia, most Primates) (Steven, 1975). Within the hemochorial type, the number (1 to 3) of trophoblastic layers intervening between the maternal and fetal bloodstreams varies (Enders, 1965).

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Authors
  1. Helen A. Padykula
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Editors and Affiliations

  1. Fertility Research, The Upjohn Company, 49001, Kalamazoo, Michigan, USA

    Frances A. Kimball Ph.D. (Research Scientist) (Research Scientist)

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© 1980 Spectrum Publications, Inc.

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Padykula, H.A. (1980). Uterine Cell Biology and Phylogenetic Considerations: An Interpretation. In: Kimball, F.A. (eds) The Endometrium. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7855-6_2

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  • DOI: https://doi.org/10.1007/978-94-011-7855-6_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-7857-0

  • Online ISBN: 978-94-011-7855-6

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