Computer-Assisted Image Analysis in Tissue-Material Interactions

Abstract

During the past century and a half, the science and practice of pathology have developed relying primarily upon the descriptive analysis of microscopic preparations. Pattern recognition remains the cornerstone of histopathologic diagnosis. Since the early years as a defined specialty, its practitioners have recognized the need for quantitative analysis to address specific questions. Numerous morphometric methods were employed, including planimetry, scaling, and direct object measurement. The availability of the microcomputer within the past decade has not only brought morphometry and image analysis to the general pathology laboratory, but has revolutionized the capacity to process images through the microscope.