Abstract
Several clinical studies have confirmed the efficacy of lithium salts in mania and in the prevention of recurrent attacks of manic-depressive illness (1, 2, 3, 4). However, not all patients benefit from this therapy. Furthermore, due to toxic side-effects, the periodic measurement of lithium serum levels during treatment is necessary. Thus, the possibility of conceiving alternative drugs with antimanic and prophylactic effects similar to those of lithium is desirable.
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References
Cade J.F.: Lithium salts in the treatment of psychotic excitement. Med.J.Aust. 36, 349–352, 1949.
Johnson G., Gershon S., Burdock E., Floyd A., Hekimian L.: Comparative effects of lithium and chlorpromazine in the treatment of acute manic states”. Br.J. Psychiatry 119, 267–276, 1971.
Prien R.F., Caffey E.M. Jr., Klett C.J.: Comparison of lithium carbonate and chlorpromazine in the treatment of mania. Arch. Gen. Psychiatry 26, 146–153, 1972.
Prien R.F., Caffey E.M. Jr., Klett C.J.: Relationship between serum lithium level and clinical response in acute manic treated with lithium. Br.J. Psychiatry, 120, 409–414, 1972.
Blom S.: Trigeminal neuralgia: its treatment with a new anticonvulsant drug G32883. Lancet I, 839–840, 1962.
Killian J.M. and Fromm G.H.: Carbamazepine (Tegretol) in the treatment of neuralgia: use and side effects. Arch. Neurol. 19, 129–136, 1968.
Davis E.H.: Clinical trials of Tegretol R in trigeminal neuralgia. Headache 9, 77–82, 1969.
Yang C.P. and Nagaswami S.: Cardiac syncope secondary to glossopharyngeal neuralgia effectively treated with carbamazepine. J. Clin. Psychiatry 39, 776–778, 1978.
Dalby M.A.: Antiepileptic and psychotropic effects of carbamazepine (Tegretol) in the treatment of psychomotor epilepsy. Epilepsia 12, 325–334, 1971.
Penry J.K. and Daly D.D.: Complex Partial Seizures: Adv. in Neurology, Vol. II, Raven Press, New York, 1975.
Rodin E.A., Rim C.S., Rennick P.M.: The effects of carbamazepine on patients with psychomotor epilepsy: results of a double blind study. Epilepsia 15, 547–561, 1974.
Dalby M.A.: Behavioural effects of carbamazepine. In: Penry J.K. and Daly D.D. (Eds.), Complex Partial Seizures, Adv. Neurology Vol.11, Raven Press, New York, 1975.
Kuhn R.: The psychotropic effect of carbamazepine in non-epileptic adults with particular reference to the drug’s possible mechanism of action. In: Epileptic Seizures — Behaviour — Pain. Ed: W. Birkmayer, Hans Huber Publ., pp. 32-48, 1975.
Kuhn-Gebhart V.: Behavioural disorders in non epileptic children and their treatment with carbamazepine. In: Epileptic Seizures — Behaviour — Pain. Ed: W. Birkmayer, Hans Huber Publ. pp. 246-267, 1975.
Puente R.M.: The use of carbamazepine in the treatment of behavioural disorders in children. In: Eplieptic Seizures. Behaviour — Pain, Ed: W. Birkmayer, Hans Huber Publ. pp. 243-247, 1975.
Okuma T., Inanaga K., Otsuki S., Sarai K., Takahashi R., Hazama H., Mori A., Watanaba M.: Comparison of antimanic efficacy of carbamazepine and chlorpromazine: a double-blind controlled study. Psychopharmacology 66, 211–217, 1979.
Okuma T., Inanaga K., Otsuki S., Sarai A., Takahashi R., Hazama H., Mori A., Watanaba M.: A preliminary double-blind study on the efficacy of carbamazepine in the prophylaxis of manic-depressive illness. Psychopharmacology 73, 95–96, 1981.
Ballenger J.C., Post R.M.: Therapeutic effects of carbamazepine in affective illness. A preliminary report. Communications in Psychopharmacology 2, 159–175, 1978.
Ballenger J.C., Post R.M.: Carbamazepine in manic depressive illness: a new treatment. Am.J. Psychiatry 137, 782–790, 1980.
Overall J.E., Gorham D.R.: The brief psychiatric rating scale. Psychiatr. Rep 10, 799–812, 1962.
Klein E., Bental E., Lerer B., Belmaker R.H.: Combination of carbamazepine and haloperidol versus placebo and haloperidol in excited psychoses: a controlled study. Arch. Gen. Psych. In Press.
Post R.M.: Carbamazepine’s acute and prophylactic effects in mania and depressive illness: An update. Intern. Drug Ther. Newsletter 17, 5–9, 1982.
Levine E., Bleck V.: Cyclic AMP-accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital and phenytoin. Epilepsia 18, 237–242, 1977.
Ebstein R., Belmaker R.H., Grunhaus L., Rimon R.: Lithium inhibition of adrenaline-stimulated adenylate cyclase in humans. Nature 259, 411–413, 1976
Marangos P.J., Post R.M., Patel J., Zander K., Parma A., Weiss S.: Specific and potent interactions of carbamazepine with brain adenosine receptors. Eur.J. Pharm. 93, 175–182, 1983.
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Del Zompo, M., Burrai, C., Piccardi, M.P., Marelli, A., Corsini, G.U. (1984). Prophylactic efficacy of carbamazepine in lithium-resistant affective disorders. In: Corsini, G.U. (eds) Current Trends in Lithium and Rubidium Therapy. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7318-6_27
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DOI: https://doi.org/10.1007/978-94-011-7318-6_27
Publisher Name: Springer, Dordrecht
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