Abstract
Parenteral nutrition involves the infusion of complex mixtures of nutrients in sufficient quantities and in such proportions as to facilitate the preservation of tissue integrity. Treatment regimens usually include a nutrient which acts as a source of energy providing fuel to meet the basal energy requirements of tissues, together with that needed to support the synthesis of cell constituents. The introduction of alternatives to glucose as energy sources was stimulated by those who found certain objections to the use of glucose. The objections were of two main types: (a) practical: glucose was thought to be more ‘damaging’ to veins than other substrates; and (b) metabolic. The metabolic objections have been based on two main lines of evidence. First, that alternative substrates are metabolized more rapidly than glucose and thus are ‘better’; and second, that the presence of insulin is required for glucose utilization and that trauma together with some disease states are associated with glucose intolerance.
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Newton, D., Connor, H., Woods, H.F. (1978). Metabolic pathways for carbohydrates in parenteral nutrition. In: Johnston, I.D.A. (eds) Advances in Parenteral Nutrition. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7188-5_3
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DOI: https://doi.org/10.1007/978-94-011-7188-5_3
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