Abstract
By means of two-dimensional immunoelectrophoresis according to the method of Clarke and Freeman1 it is possible to determine quantitatively at least 30 immunologically distinct rat serum proteins’. Fifteen of these proteins were identified by specific staining methods, physicochemical parameters or biochemical functions (Table 39.1).
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References
Clarke, M. H. G. and Freeman, T. (1968). Quantitative immunoelectrophoresis of human serum proteins. Clin. Sci. 35, 403.
DiRosa, M. D. (1972). Biological properties of carrageenan. J. Pharm. Pharmacol., 24, 89
Abd-El-Fattah, M., Scherer, R. and Ruhenstroth-Bauer, G. (1976). Application of quantitative two-dimensional immunoelectrophoresis in the study of the acute-phase reaction following injection of the lipid A component of bacterial lipopolysaccharides in rats. J. Mol. Med. 1, 211.
Billingham, M. E. and Gordon, A. H. (1975). The role of the acute phase reaction in inflammation. In: Future Trends in Inflammation II (J.-P. Giroud, D. A. Willoughby and G. P. Velo, eds.) pp. 195–200. ( Basel and Stuttgart: Birkhäuser Verlag )
Pekarek, R., Wannemacher, R., Powanda, M., Abeles, F., Mosher, D., Dintermann, R. and Beisel, W. (1974). Further evidence that leukocytic endogenous mediator (LEM) is not endotoxin. Life Sci., 14, 1765
Pekarek, R., Wannemacher, R. W., Chapple, F. E., Powanda, M. C. and Beisel, W. (1972). Further characterization and species specificity of leukocytic endogenous mediator (LEM). Proc. Soc. Exp. Biol. Med., 141, 643
Kampschmidt, R. F. and Upchurch, H. F. (1974). Effect of leukocytic endogenous mediator on plasma fibrinogen and haptoglobin. Proc. Soc. Exp. Biol. Med., 146, 904
Eddington, C. L., Upchurch, H. F. and Kampfschmidt, R. F. (1972). Quantitation of plasma a-2-AP globulin before and after stimulation with leukocytic extracts. Proc. Soc. Exp. Biol. Med., 139, 565
Pekarek, R. S., Powanda, M. C. and Wannemacher, R. W. (1972). The effect of leukocytic endogenous mediator on serum copper and coeruloplasmin concentrations in the rat. Proc. Soc. Exp. Biol. Med., 141, 1029
Beisel, W. R. (1975). Metabolic response to infection. In: Annual Review of Medicine (W. P. Creger, C. H. Coggins and E. W. Hancock, eds.) Vol. 26, pp. 9–20
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Scherer, R., Abd-El-Fattah, M., Ruhenstroth-Bauer, G. (1977). Some applications of quantitative two-dimensional immunoelectrophoresis in the study of the systemic acute-phase reaction of the rat. In: Willoughby, D.A., Giroud, J.P., Velo, G.P. (eds) Perspectives in Inflammation. Future Trends in Inflammation, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7185-4_39
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DOI: https://doi.org/10.1007/978-94-011-7185-4_39
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