Abstract
Exposure of mammalian cells to mutagenic chemicals may result in a variety of detectable changes in the genetic material. The genetic changes to be described here are those involving whole chromosomes and are generally referred to as chromosome aberrations or anomalies. Unlike gene or point mutations, chromosome aberrations can be observed under a conventional light microscope at the metaphase stage of cell division (Figure 7.1).
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Dean, B.J. (1979). Cytogenetic aspects of mutagenicity testing. In: Paget, G.E. (eds) Mutagenesis in Sub-Mammalian Systems. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6639-3_7
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DOI: https://doi.org/10.1007/978-94-011-6639-3_7
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-011-6641-6
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