Abstract
In batch culture, the end of exponential growth triggers many microorganisms to synthesize a variety of compounds not produced (or produced at low level) during growth. Among the compounds produced at the end of growth are antibiotics and extracellular enzymes, some of which are of industrial importance. The molecular mechanisms regulating the timing of the synthesis of these compounds is not known but their production appears to be in response to nutrient starvation. In addition the synthesis of many of these compounds is repressed by the availability of readily metabolized nutrients such as glucose.
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© 1985 Robert E. Glass and Jaroslav Spižek
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Chambliss, G.H., Nicholson, W.L. (1985). Regulation of α-Amylase Synthesis in Bacillus Subtilis . In: Glass, R.E., Spižek, J. (eds) Gene Manipulation and Expression. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6565-5_4
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DOI: https://doi.org/10.1007/978-94-011-6565-5_4
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