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Is normothermic preservation an alternative to hypothermic preservation?

  • R. N. Dunn
  • F. K. Merkel
  • D. Roseman
  • M. Haklin
  • K. English

Abstract

Currently, clinical preservation is at a standstill, the approximate maximum safe cold periods for kidneys, livers and hearts being 72, 10 1/2 and 3 1/2h, respectively; a tiny fraction of their in vivo lifespan1–3. Neither the exact nature of the limiting factors nor a method for circumventing them is at hand. It seems likely that inactivation of the sodium pump, depletion of respiratory chain nucleotides, cellular swelling and/or membrane injury result in deterioration of the organ over time1.

Keywords

Hydroxyethyl Starch Organ Preservation Hypothermic Preservation Fluorocarbon Emulsion Ambient Partial Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© MTP Press Limited 1982

Authors and Affiliations

  • R. N. Dunn
  • F. K. Merkel
  • D. Roseman
  • M. Haklin
  • K. English

There are no affiliations available

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