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Energetics and mitochondria

  • H. Feinberg

Abstract

A recent editorial noted that kidney preservation techniques have changed little for over a decade1. Storage beyond a 7-10-day period is not yet possible. In part, this was attributed to ‘lack of understanding of the metabolic requirements of the ex vivo hypothermic-perfused organ, particularly as it relates to function and pathways that are altered by hypothermia’. The same comments are applicable to liver and heart preservation; indeed these organs cannot be successfully stored for more than 24 h.

Keywords

Adenine Nucleotide Proton Gradient Citric Acid Cycle Organ Preservation Adenine Nucleotide Translocase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© MTP Press Limited 1982

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  • H. Feinberg

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