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Functional characteristics of neutrophil granulocytes from children with recurrent respiratory infections

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Inborn Errors of Immunity and Phagocytosis

Abstract

Impaired function of polymorphonuclear neutrophil granulocytes (PMN) is associated with recurrent bacterial infections. Inherited defects in the chemotactic response1 and in different microbicidal enzymes have been described2. It is however unclear to what extent the granulocyte function in patients with a history of recurrent infections is impaired.

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References

  1. Miller, M. E., Oski, F. A. and Harris, M. B. (1971). Lazy leucocyte syndrome. Lancet, i, 665

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  2. Klebanoff, S. J. (1971). Intraleukocytic microbicidal defects. Ann Rev Med., 22, 39

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  3. Stossel, Th. (1973). Evaluation of opsonic and leukocyte function with a new spectrophotometric test in patients with infection and with phagocytic disorders. Blood, 42, 121

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© 1979 The Society for the Study of Inborn Errors of Metabolism

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Wandall, J.H., Binder, V., Friis, B., Bech, B. (1979). Functional characteristics of neutrophil granulocytes from children with recurrent respiratory infections. In: Güttler, F., Seakins, J.W.T., Harkness, R.A. (eds) Inborn Errors of Immunity and Phagocytosis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6197-8_25

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  • DOI: https://doi.org/10.1007/978-94-011-6197-8_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6199-2

  • Online ISBN: 978-94-011-6197-8

  • eBook Packages: Springer Book Archive

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