Hormone Replacement Therapy and Breast and Gynecologic Cancers

  • P. Sismondi
  • N. Biglia
  • M. Giai
  • R. Ponzone
  • C. Campagnoli
Part of the Medical Science Symposia Series book series (MSSS, volume 11)


The most serious obstacle to the diffusion of hormone replacement therapy (HRT) in menopause is the concern that HRT, either estrogens alone or combined with progestins, may enhance morbidity and mortality due to the development of malignant neoplasia in reproductive organs, particular breast and endometrial cancer. We reviewed the literature on breast and gynecological cancer risk for HRT users, specifically addressing the issues of duration, dose, and type of hormonal compounds in influencing cancer risk.


Breast Cancer Ovarian Cancer Breast Cancer Risk Endometrial Cancer Hormone Replacement Therapy 
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Copyright information

© Springer Science+Business Media Dordrecht 1997

Authors and Affiliations

  • P. Sismondi
  • N. Biglia
  • M. Giai
  • R. Ponzone
  • C. Campagnoli

There are no affiliations available

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