Abstract
Pulmonary edema is a prominent component of the acute respiratory distress syndrome (ARDS), especially during the first few days of the illness, responsible in large part for the disturbance in gas exchange and pulmonary mechanics. Accordingly, it seems reasonable to try to limit the accumulation and to hasten the resolution of pulmonary edema, if this goal can be reached with therapeutic maneuvers that don’t, themselves, contribute to the already high morbidity and mortality of this syndrome. A prime example of such a dilemma is the problem of trying to limit the development of pulmonary edema by manipulating fluid management, in which attempts at fluid restriction, diuresis, or even renal replacement therapy may have a negative impact on renal function. In this chapter, we review the evidence relevant to this long-standing, and to some extent, still unresolved, clinical predicament.
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References
Bernard GR, Artigas A, Brigham KL, et al. The American-European Consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994; 149: 818–24.
Schuster DP, What is acute lung injury? What is ARGS? Chest 1995; 107: 1721–6.
Meyrick B. Pathology of the adult respiratory distress syndrome. Crit Care Clin 1986; 2(3): 405–428.
Tomashefski Jr JF. Pulmonary pathology of the adult respiratory distress syndrome. Clin Chest Med 1990; 11 (4): 593–620.
Schuster DP. Pulmonary edema. In: Pulmonary Diseases and Disorders. AP Fishman (ed). McGraw Hill Publ., Philadelphia. (In Press).
Prewitt RM, McCarthy J, Wood LDH. Treatment of acute low pressure pulmonary edema in dogs. Relative effects of hydrostatic and oncotic pressure, nitroprusside, and positive end-expiratory pressure. J Clin Invest 1981; 67: 409–18.
Huchon GJ, Hopewell PC, Murray JF. Interactions between permeability and hydrostatic pressure in per-fused dogs’ lungs. J Appl Physiol 1981; 50: 905–11.
Molloy WD, Lee KY, Girling L, Prewitt RM. Treatment of canine permeability pulmonary edema: short-term effects of dobutamine, furosemide, and hydralazine. Circulation 1985; 72: 1365–71.
Townsley MI, Lim EH, Sahawneh TM, Song W. Interacticin of chemical and high vascular pressure injury in isolated canine lung. J Appl Physiol 1990; 69: 1647–64.
Allen SJ, Drake RE, Katz J, Gabel JC, Laine GA. Lowered pulmonary arterial pressure prevents edema after endotoxin in sheep. J Appl Physiol 1987; 63: 1008–11.
Berner ME, Teague WG, Scheerer RG, Bland RD. Furosemide reduces lung fluid filtration in lambs with lung microvascular injury from air emboli. J Appl Physiol 1989; 67: 1990–6.
Long R, Breen PH, Mayers I, Wood LDH. Treatment of canine aspiration pneumonitis: fluid volume reduction vs fluid volume expansion. J Appl Physiol 1988; 65: 1736–44.
Sznajder JI, AR Zucker, Wood LDH, Long GR. The effects of plasmapheresis and hemofiltration on canine acid aspiration pulmonary edema. Am Rev Respir Dis 1986; 134: 222–8.
Winn R, Stothert J, Nadir B, Hildebrandt J. Lung fluid balance, vascular permeability, and gas exchange after acid aspiration in awake goats. J Appl Physiol 1984; 56: 979–85.
Zucker AR, Sznajder JI, Becker CJ, Berger S, Wood LDH. The pathophysiology and treatment of canine kerosene pulmonary injury: effects of plasmapheresis and positive end-expiratory pressure. J Crit Care 1989; 4: 184–93.
Sivak ED, Tita J, Meden G, Ishigami M, Graves J, Kavlich J, Stowe NT, Magnuisson MO. Effects of furosemide versus isolated ultrafiltration on extravascular lung water in oleic acid-induced pulmonary edema. Crit Care Med 1986; 14: 48–51.
Chernicki JAW, Wood LDH. Effect of furosemide in canine low-pressure pulmonary edema. J Clin Invest 1504–94.
Kollef MH, Schuster DP. The acute respiratory distress syndrome. N Engl J Med 1995; 332: 27–37.
Schuster DP, Kollef M. The acute respiratory distress syndrome. Disease-a-Month (in press).
Ali J, Unruh H, Skoog C, Goldberg HS. The effect of lung edema on pulmonary vasoactivity of furosemide. J Surg Res 1983; 35: 383–90.
Ali J, Wood LDH. Pulmonary vascular effects of furosemide on gas exchange in pulmonary edema. J Appl Physiol 1984; 57: 160–7.
Stevens EL, Uyehara CFT, Southgate WM, Nakamura KT. Furosemide differentially relaxes airway and vascular smooth muscle in fetal, newborn, and adult guinea pigs. Am Rev Respir Dis 1992; 146: 1192–7.
Rusch VW, Artman L, Cheney FW. Effect of furosemide on fully established low pressure pulmonary edema. J Surg Res 1986; 41: 141–5.
Cheney FW, Bishop MJ, Chi EY, Eisenstein BL. Effect of regional alveolar hypoxia on permeability pulmonary edema formation in dogs. J Appl Physiol 1987; 62: 1690–7.
Bishop MJ, Boatman ES, Webster R, Ivey TD, Cheney FW, Effects of lobar pulmonary blood flow on the evolution of oleic acid lung injury in dogs. J Surg Res 1986; 41: 394–400.
Dauber IM, Weil JV. Lung injury edema in dogs. Influence of sympathetic ablation. J Clin Invest 1983; 72: 1977–86.
Leeman M, Closset J, Vachiery J, Lejeune P, Melot C, Naeije R. Sino-aortic deafferentation reduces intrapulmonary shunt in dogs with oleic acid lung injury. J Appl Physiol 1989; 67: 833–8.
Schuster DP, Stephenson AH, Holmberg S, Sandiford P. Effect of eicosanoid inhibition on the development of pulmonary edema after acute lung injury. J Appl Physiol 1996; 80: 915–23.
Cheney FW, Eisenstein BL, Bishop MJ. Alveolar hypoxia, inhibition of hypoxic pulmonary vasoconstriction, and permeability edema. Respir Physiol 1989; 75: 11–8.
Hasinoff I, Ducas J, Prewitt RIVI. Increased cardiac output increases lung water in canine permeability pulmonary edema. J Crit Care 1988; 3: 225–31.
Takeda K, MJ Knapp, WG Wolfe, Crapo JD. Hypoxia enhances unilateral lung injury by increasing blood flow to the injured lung. J Appl Physiol 1987; 63: 2516–23.
Bone RC. Treatment of adult respiratory distress syndrome with diuretics, dialysis, and positive end-expiratory pressure. Crit Care Med 1998; 6: 136–9.
Costello JL, Dorinsky PM, Gadek JE. Edema reduction improves clinical abnormalities in ARDS: a clinical trial of aggressive diuretic therapy. Am Rev Respir Dis 1987; 135: A9.
Simmons RS, Berdine GG, Seidenfeld JJ, Prihoda TJ, Harris GD, Smith JD, Gilbert J, Mota E, Johanson, Jr. Fluid balance and the adult respiratory distress syndrome. Am Rev Respir Dis 1987; 135: 924–9.
Humphrey H, Hall J, Sznajder I, Silverstein M, Wood L. Improved survival in ARDS patients associated with a reduction in pulmonary capillary wedge pressure. Chest 1990; 97: 1176–80.
Lowell JA, Schifferdecker C, Driscoll DF, Benotti PN, Bistrain BR. Postoperative fluid overload: not a benign problem. Crit Care Med 1990; 18: 728–33.
Mitchell JP, Schuller D, Calandrino FS, Schuster DP. Improved outcome based on fluid management in critically ill patients requiring pulmonary artery catheterization. Am Rev Respir Dis 1992; 145: 990–8.
Fowler AA, Hamman RF, Zerbe GO, Benson KM, Hyers TM. Adult respiratory distress syndrome. Prognosis after onset. Am Rev Respir Dis 1985; 132: 472–8.
Chertow GM, Christiansen CL, Cleary PD, Munro C, Lazarus M. Prognostic stratification in critically ill patients with acute renal failure requiring dialysis. Arch Intern Med 1995; 155: 1505–11.
Brivet FG, Kleinknecht DJ, Loirat P, Landais PJM, The French Study Group on Acute Renal Failure. Acute renal failure in intensive care units: causes, outcome, and prognostic factors of hospital mortality: A prospective, multicenter study. Crit Care Med 1996; 24: 192–8.
Lowell JA, Schifferdecker C, Driscoll DF, Benotti PN, Bistrian BR. Postoperative fluid overload: not a benign problem. Crit Care Med 1990; 18: 728–33.
Ellison DH. The physiologic basis of diuretic synergism: its role in treating diuretic resistance. Ann Intern Med 1991; 114: 886–94.
Schuller D, Lynch JP. Prospective, randomized, comparative trial of continuous vs. bolus furosemide infusion in the intensive care unit [abstract]. Chest 1994; 106: 157S.
Rose B. Diuretics. Kidney Int 1991; 39: 336–352.
Hakim R, Winegrad RL, Parker RA. Effect of dialysis membrane in the treatment of patients with acute renal failure. N Engl J Med 1994; 331: 1338–42.
Schiffl H, Lang SM, Koenig A, Strasser T, Haider MC, Held E. Biocompatible membranes in acute renal failure: prospective case-controlled study. Lancet 1994; 344: 570–2.
Grootendorst AF, van Bommel EFH, van der Hoven B, van Leengoed LAMG, van Osta ALM. High volume hemofiltration improves right ventricular function in endotoxin-induced shock in pig. Intensive Care Med 1992; 18: 235–40.
Bellomo R, Tipping P, Boyce N. Continuous veno-venous hemofltration with dialysis removes cytokines from the circulation of septic patients. Crit Care Med 1993; 21: 522–6.
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Schuster, D.P., Windus, D. (1998). Acute renal failure in acute respiratory distress syndrome. In: Critical Care Nephrology. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5482-6_88
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DOI: https://doi.org/10.1007/978-94-011-5482-6_88
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