Abstract
Periodontitis is a chronic infectious and inflammatory disease which afflicts approximately three quarters of the world’s adult population over the age of thirty-five. Recently published studies have demonstrated that long-term administration (≥6 months) of non-steroidal anti-inflammatory drugs (NSAIDs) can halt the progressive loss of alveolar bone associated with this disease. The safe and efficacious twice daily use for six months of 0.1% ketorolac tromethamine oral rinse for the prevention of periodontal disease progression in adults has recently been demonstrated. This presentation summarizes our results to date regarding the pharmacokinetics, pharmacodynamics, safety and efficacy of the topical oral rinse form of this potent NSAID in patients with periodontitis.
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© 1997 Springer Science+Business Media Dordrecht
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Cavanaugh, P.F. (1997). The Use of Ketorolac Tromethamine Oral Rinse for the Treatment of Periodontitis in Adults. In: Rainsford, K.D. (eds) Side Effects of Anti-Inflammatory Drugs IV. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5394-2_33
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DOI: https://doi.org/10.1007/978-94-011-5394-2_33
Publisher Name: Springer, Dordrecht
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