Abstract
Injection into various parts of the peridural space has been advocated for the management of sciatica since 1930 (1), but with the findings of Mixter and Barr (2) in 1934, linking the signs and symptoms of sciatica with a herniated nucleus pulposus, surgery has continued to be the definitive therapy for this problem. However, over the years except in patients with a rapidly progressive neural deficit, surgery has provided disappointing therapeutic results, so efforts to find a non-surgical therapeutic approach have continued. From a theoretical point of view, two approaches to the problem of non-surgical therapy have been developed, one aiming to remove the etiologic mechanism and the other aiming to modify the response to that mechanism.
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Winnie, A.P. (1998). Epidural Steroids. In: Ashburn, M.A., Fine, P.G., Stanley, T.H. (eds) Pain Management and Anesthesiology. Developments in Critical Care Medicine and Anesthesiology, vol 33. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5145-0_20
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DOI: https://doi.org/10.1007/978-94-011-5145-0_20
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