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Cyclins and gap junctions in liver growth and repair

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Liver Growth and Repair

Abstract

Cyclin and gap junction proteins are intimately involved in cell regulation and communication. In fact, both gene families are dramatically modulated during the synchronized cell cycles induced by liver regeneration following partial hepatectomy. This chapter begins with an introduction to the cyclin gene family, and continues with a discussion of the various cyclin functions in cellular control, with emphasis on eukaryotic cells and in particular the mammalian liver. Finally, we discuss gap junction proteins and their roles in liver growth and repair.

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Authors and Affiliations

  1. Department of Genetics, University of Minnesota, Minneapolis, Minnesota, USA

    Janeen H. Trembley

  2. Department of Cell Biology, University of Minnesota, Minneapolis, Minnesota, USA

    Janeen H. Trembley & Clifford J. Steer

  3. Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA

    Betsy T. Kren & Clifford J. Steer

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  1. Janeen H. Trembley
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Alastair Strain Anne Mae Diehl

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Trembley, J.H., Kren, B.T., Steer, C.J. (1998). Cyclins and gap junctions in liver growth and repair. In: Strain, A., Diehl, A.M. (eds) Liver Growth and Repair. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4932-7_13

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