Abstract
As is now well established, PBC can manifest itself as a benign or a progressive disease1–3. Several investigators tried to evaluate various clinical and biochemical criteria in order to distinguish these two forms and to predict the clinical outcome; several prognostic models have been established4–6. However, although these parameters do seem to allow the determination of the appropriate time for liver transplantation, they are not suitable for differentiating between patients with a benign and those with a progressive course during the early stages of the disease.
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Klein, R., Berg, P.A. (1998). Significance of antimitochondrial antibody profiles in primary biliary cirrhosis. In: Lindor, K.D., Heathcote, E.J., Poupon, R. (eds) Primary Biliary Cirrhosis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4884-9_4
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DOI: https://doi.org/10.1007/978-94-011-4884-9_4
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