Abstract
Factor VIIa, a vitamin K-dependent plasma serine protease, is the first enzyme in the coagulation cascade. The majority of this glycoprotein circulates as the inert zymogen (factor VII) with a concentration in pooled normal plasma of about 470 ng/ml (9.4 nmol/L)1. However, low levels of activated factor VII (factor VIIa) are also present in the circulation. Typically, factor VIIa makes up less than 1% of the total factor VII in plasma2.
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Morrissey, J.H. (1999). Activated factor VII. In: Jespersen, J., Bertina, R.M., Haverkate, F. (eds) Laboratory Techniques in Thrombosis — a Manual. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4722-4_9
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DOI: https://doi.org/10.1007/978-94-011-4722-4_9
Publisher Name: Springer, Dordrecht
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