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Informed Consent Under Scrutiny, Suggestions for Improvement

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Human Experimentation
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Abstract

At the end of this centennial, as the 50th anniversary of the Nuremberg Code is commemorated, the consensus on individual autonomy and insistence on informed consent to research, that for the past 50 years has characterized bioethical thinking in human experimentation, is being scrutinized.

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References

  1. Levine RJ. Ethics and regulations of clinical research. 2nd ed. New Haven, Conn: Yale University Press, 1988.

    Google Scholar 

  2. The World Medical Association, Inc. World Medical Association Declaration of Helsinki, as amended by the 41st World Assembly Hong Kong, September 1989. Ferney-Voltaire, France, September 1989.

    Google Scholar 

  3. Rothman DJ. Book reviews, the ethics of research involving human subjects. N Engl J Med 1997; 336: 882.

    Article  Google Scholar 

  4. Adedeji OA. Informed consents in clinical trials. Br Med J 1993; 307: 1494–1497.

    Article  Google Scholar 

  5. Waldrom HA, Cookson RF. Avoiding the pit falls of sponsored multicentre research in general practice. Br Med J 1993; 307: 1331–1334.

    Article  Google Scholar 

  6. Rothman KJ, Michels KB. The continuing unethical use of placebo. N Engl J Med 1994; 331: 394–398.

    Article  PubMed  CAS  Google Scholar 

  7. Kant I. Kritik der Urteilskraft. Leipzig: Dr Max Janecke, Verlagsbuchhandlung, 1920.

    Google Scholar 

  8. Schopenhauer A. Die Welt als Wille und Vorstellung. Berlin: Springer Verlag, 1819.

    Google Scholar 

  9. Newman JH. An essay in aid of a grammar of assent. Oxford, UK: Oxford University Press, 1870.

    Google Scholar 

  10. Cleophas TJ. Clinical trials in chronic diseases: new endpoints. Clin Research& Reg Affairs 1995; 12: 273–283.

    Article  Google Scholar 

  11. Cleophas TJ. Lack of real science of symptom-based care of patients with chronic benign disease. Clin Research & Reg Affairs 1996; 13: 167–181.

    Article  Google Scholar 

  12. Griffith PL. The 5 minute consult. Philadelphia: Lea & Febinger, 1994.

    Google Scholar 

  13. Christakis N. Ethical decisions made case by case. In: The ethics of research involving human subjects: facing the 21st century. Frederick, Md: University Publishing group, 1990, pp434–445.

    Google Scholar 

  14. Cleophas TJ, Van der Meulen J, Kalmansohn RB. Clinical trials: specific problems associated with the use of control groups. Br J Clin Pharmacol 1997; 43: 219–221.

    Article  PubMed  CAS  Google Scholar 

  15. Hacker A. Research in non-Western societies. The NY Review of Books 1990; Nov 22: 64–65.

    Google Scholar 

  16. Cohen Stuart MH. Informed consent. Medisch Contact 1998; 53: 603.

    Google Scholar 

  17. EFFECT Study Group. Clinical study protocol study SH-AHM-0016. Saint Josephe Hospital Gouda, Netherlands, centre of coordination (Dr RP Hoogma), November 4, 1997.

    Google Scholar 

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© 1999 Springer Science+Business Media Dordrecht

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Cleophas, T.J. (1999). Informed Consent Under Scrutiny, Suggestions for Improvement. In: Human Experimentation. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4663-0_12

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  • DOI: https://doi.org/10.1007/978-94-011-4663-0_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-5827-5

  • Online ISBN: 978-94-011-4663-0

  • eBook Packages: Springer Book Archive

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