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Malignant Tumors of the Appendix

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Abstract

The appendix is an embryonic remnant of the bursa of Fabricius. It shows great individual variation in location and size. It generally arises at the base of the caecum at the confluence of the taenia. The tip may be located in the pelvis or high in the right upper quadrant behind the colon. Its origin is behind the colon; thus by definition, the appendix is always retrocaecal; however the tip is located behind the colon in only 65% of cases.

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References

  • Adolfsson G., Benign and malignant tumors of the appendix, Acta Chir.Scand. 140: 151–155 (1974).

    PubMed  CAS  Google Scholar 

  • Andersson A., Bergdahl L., Boquist L., Primary carcinoma of the appendix, Annals Surg. 183: 53–57 (1976).

    Article  CAS  Google Scholar 

  • Anurahma A.F., Primary adenocarcinoma of the vermiform appendix, West Virg.Med.J. 73: 296–301 (1977).

    Google Scholar 

  • Bodon G.R., Dressler JA., Metastatic carcinoma of the right testicle from primary carcinoma of the appendix, J.Urol. 97: 885–887 (1967).

    PubMed  CAS  Google Scholar 

  • Boulenger M., Ducroux A., Dupaty A., Moliné J., Montagnon J., Ferry C., Adénocarcinome de l’appendice iléo-caecal (sur moignon appendiculaire), Lyon Chirurg. 76: 258–289 (1980).

    Google Scholar 

  • Carr N.J., MacCarthy W.F., Sobin L.H., Epithelial noncarcinoid tumors and tumor-like lesions of the appendix, Cancer 75: 757–768 (1995).

    Article  PubMed  CAS  Google Scholar 

  • Carr N.J., Sobin L.H., Unusual tumors of the appendix and pseudomyxoma peritonei, Sem.Diagn.Pathol. 13: 314–325 (1996).

    CAS  Google Scholar 

  • Cerarne M.A., A 25-year review of adenocarcinoma of the appendix, Dis.Col.Rect. 31: 145–150 (1988).

    Article  Google Scholar 

  • Chang P., Attiveh F.F., Adenocarcinoma of the appendix, Dis. Col. Rect. 23: 176–180 (1981).

    Article  Google Scholar 

  • Chen K.T., Spaulding R.W., Appendiceal carcinoma masquerading as primary bladder carcinoma, J.Urol. 145: 821–8222 (1991).

    PubMed  CAS  Google Scholar 

  • Coblentz M.G., Filippone D.R., Primary adenocarcinoma of the jejunum and coexisting primary adenocarcinoma of the vermiform appendix, Surgery 77: 160–164 (1975).

    PubMed  CAS  Google Scholar 

  • Collins D., 71.000 human appendix specimens. A final report over 40 years., Am.J.Proctol. 1: 265–281 (1963).

    Google Scholar 

  • Connor S.J., Hanna G.B., Frizelle F.A., Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7970 appendectomies, Dis.Colon Rectum 41: 75–80 (1998).

    Article  PubMed  CAS  Google Scholar 

  • Conte C., Petrelli N.J., Stulc J., Herrera L., Mittelman A., Adenocarcinoma of the appendix, Surg.Gyn.Obst. 166: 451–453 (1988).

    PubMed  CAS  Google Scholar 

  • Dahms S.E., Hohenfellner M., Eggersmann C., Lampel A., Golz R., Thüroff J.W., Appendix carcinoma invading the urinary bladder, Urol.Int. 58: 124–127 (1997).

    Article  PubMed  CAS  Google Scholar 

  • Das Gupta T.K., Paglia M.A., Primary malignant tumors of the appendix (nine cases with unusual presentation), N. Y.Stat J.Med.66: 890–896 (1966).

    Google Scholar 

  • Deans G.T., Spence R.A., Neoplastic lesions of the appendix, Brit. J. Surg. 82:299–306 (1995).

    Article  PubMed  CAS  Google Scholar 

  • Dymock R.B., Pathological changes in the appendix-a review of 1000 cases., Pathology 9: 331–339 (1977).

    Article  PubMed  CAS  Google Scholar 

  • Eckert M., Gerassimidis T., Schultess F., Hamman J., Beck I., Das primäre Appendix Karzinom, Fortsch.Med. 96: 1205–1208 (1978).

    CAS  Google Scholar 

  • Edmondson H.T., Hobes M.L., Primary adenocarcinoma of the appendix, Am.Surgeon 33: 717–732 (1967).

    PubMed  Google Scholar 

  • Ferro M., Anthony P.P., Adenocarcinoma of the appendix, Dis.Col. Rect. 28:457–459 (1985).

    Article  CAS  Google Scholar 

  • Gamble H.A., Adenocarcinoma of the appendix: an unusual case and review, Dis.Col.Rect. 19: 621–625 (1976).

    Article  Google Scholar 

  • Gilhome R.W., Johnstone D.H., Cxlark J., Kyle J., Primary adenocarcinoma of the vermiform appendix: report of a series of ten cases and review of the literature, Brit. J. Surg. 71: 553–555 (1984).

    Article  PubMed  CAS  Google Scholar 

  • Guivarch M., Roullet-Audy J.C., Barbagelatta M., Marquand J., Noureddine M., L’adénocarcinome de l’appendice, Ann.Chir. 36: 340–348 (1982).

    CAS  Google Scholar 

  • Hananel N., Powsner E., Wolloch Y., Adenocarcinoma of the appendix: an unusual disease, Eur.J.Surg. 164: 859–862 (1998).

    Article  PubMed  CAS  Google Scholar 

  • Harris G.J., Urdaneta L.F., Mitros F.A., Adenocarcinoma of the vermiform appendix, J.Surg.Oncol. 44: 218–224 (1990).

    Article  PubMed  CAS  Google Scholar 

  • Jacquet P., Sugarbaker P.H., Current methodologies for clinical assessment of patients with peritoneal carcinomatosis, J.Exp.Clin. Canc.Res. 15:49–58 (1996).

    Google Scholar 

  • Javier Gomez-Roman J., Fernando Val-Bernal J., Fernandez F., Mucinous cystadenocarcinoma of the vermiform appendix presenting as a renal tumor, J.Urology 154: 1122–1124 (1995).

    Article  CAS  Google Scholar 

  • Lenriot J.P., Huguier M., Adenocarcinoma of the appendix, Am.J. Surg. 155:470–475 (1988).

    Article  PubMed  CAS  Google Scholar 

  • Lyss A.P., Appendiceal malignancies, Sem.Oncol. 15: 129–137 (1988).

    CAS  Google Scholar 

  • Merino M.J., Edmonds P., LiVolsi V., Appendiceal carcinoma metastatic to the ovaries and mimicking primary ovarian carcinoma, Int.J. Gynecol.Pathol. 4:110–120 (1985).

    Article  PubMed  CAS  Google Scholar 

  • Mehzad M., Aflaki B., Afghari H., Adenocarcinoma of the appendix: report of an unusual case, Dis.Col.Rect. 21: 205–206 (1978).

    Article  CAS  Google Scholar 

  • Nitecki S.S., Wolff B.G., Schlinkert R., Sarr M.G., The natural history of surgically treated primary adenocarcinoma of the appendix, Ann. Surg. 219: 51–57 (1994).

    Article  PubMed  CAS  Google Scholar 

  • Otto R.E., Ghislandi E.V., Lorenzo G.A., Conn J., Primary appendiceal adenocarcinoma, Am.J.Surg. 120: 704–706 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Paone J.F., Bixler Y.J., Imbembo AL., Primary mucinous adenocarcinoma of the appendix with bilateral Krukenberg ovarian tumors,, Johns Hopkins Med.J. 143: 43–47 (1978).

    PubMed  CAS  Google Scholar 

  • Peck J.J., Managment of carcinoma discovered unexpectedly at ope-ration for acute appendicitis, Am.J.Surg. 155: 685–686 (1988).

    Article  Google Scholar 

  • Proulx G.M., Willett C.G., Daley W., Snellito P.C., Appendiceal carcinoma: patterns of failure following surgery and implications for adjuvant therapy, J.Surg.Oncol. 66: 51–53 (1997).

    Article  PubMed  CAS  Google Scholar 

  • Ronnett B.M., Kurman R.J., Shmookler B.M., Sugarbaker P.H., Young R.H., The morphologic spectrum of ovarian metastases of appendiceal adenocarcinomas, Am.J.Surg.Pathol. 21: 1144–1155 (1997).

    Article  PubMed  CAS  Google Scholar 

  • Rutledge R.H., Alexander J.W., Primary appendiceal malignancies: rare but important, Surgery 111: 244–250 (1992).

    PubMed  CAS  Google Scholar 

  • Schlatter M.G., MacKone T.K., Schölten D.J., Bonnell B.W., De Krijger L.L., Primary appendiceal adenocarcinoma, Am. Surgeon 53:434–437 (1987).

    PubMed  CAS  Google Scholar 

  • Schmid K. W., Glaser K., Wykypiel H., Feichtinger H., Synchronous adenocarcinoma of the transverse colon, the gallbladder and the vermiform appendix, Klin.Wochenschr. 66: 1093–1096 (1988).

    Article  PubMed  CAS  Google Scholar 

  • Schmutzer K.J., Bayar M., Zaki A.E., Regan J.F., Poletti JB., Tumors of the appendix, Dis.Col.Rect. 18: 324–331 (1975).

    Article  CAS  Google Scholar 

  • Stevens K.J., Dunn W.K., Balfour T., Pseudomyxoma extraperitonei: a lethal complication of mucinous adenocarcinoma of the appendix, Am.J.Gastroenterol. 92: 1920–1922 (1997).

    PubMed  CAS  Google Scholar 

  • Sugarbaker P.H., Chang D., Koslowe P., Peritoneal carcinomatosis from appendiceal cancer: a paradigm for treatment of abdomino-pelvic dissemination of gastrointestinal malignancy, Acta Chir. Austr. 28:4–8 (1996).

    Article  Google Scholar 

  • Thomas R., Barnhill D., Worsham F. et al., Krukenberg tumor of the ovary from an occult appendiceal primary: case report and review of the literature, Obst.Gynec. 65: 95–98 (1985).

    Google Scholar 

  • Thomas R.M., Sobin L.H., Gastrointestinal cancer, Cancer 75: 154–170 (1995).

    Article  PubMed  CAS  Google Scholar 

  • Thorsen P., Dybdahl H., Sogaard H., Moller B.R., Ovarian tumors caused by metastatic tumors of the appendix: two case reports, Eur.J. Obst.Gyn.Repr.Biol. 40: 67–71 (1991).

    Article  CAS  Google Scholar 

  • Tripodi J., Perlmutter S., Rudansky S., Kim D.K., Burakoff R;, Primary adenocarcinoma of the appendix: an unusual presentation, Am.J. Gastroent. 90: 661–662 (1995).

    PubMed  CAS  Google Scholar 

  • Uihlein A., MacDonald JR., Primary carcinoma of the appendix ressembling carcinoma of the colon, Surg.Gyn.Obst. 76: 711–714 (1943).

    Google Scholar 

  • Wagner K.M., Thompson J., Herlinger H., Caroline D., Thirteen primary adenocarcinomas of the ileum and appendix, Cancer 49: 797–801 (1982).

    Article  PubMed  CAS  Google Scholar 

  • Weber V., Appendix Karzinom, Med.Klin. 72: 956–959 (1977).

    PubMed  CAS  Google Scholar 

  • Wolff M., Ahmed N., Epithelial neoplasms of the vermiform appendix: an adenocarcinoma of the appendix, Cancer 37: 2493–2510 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Yamada T., Murao Y., Nakamura T., Tabuse H., Miyamoto S., Imai S., Nakano H., Primary adenocarcinoma of the appendix, colonic type, associated with perforating peritonitis in an elderly patient, J.Gastroenterol. 32: 658–662 (1997).

    Article  PubMed  CAS  Google Scholar 

  • Zannoni U., Masci C., Bazzocchi R., Gandolfo F., Pezzi A., Alampi G., Biasco G., Cancer of the appendix in long-standing ulcerative colitis, Tumori 83: 958–959 (1998).

    Google Scholar 

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© 2000 Springer Science+Business Media Dordrecht

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Debois, J.M. (2000). Malignant Tumors of the Appendix. In: Selected Topics in Clinical Oncology. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4100-0_16

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  • DOI: https://doi.org/10.1007/978-94-011-4100-0_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5797-4

  • Online ISBN: 978-94-011-4100-0

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