Abstract
A system of molecular architecture that consists of fused 6-membered carbocyclic and heterocyclic rings and orients heteratom binding sites toward a molecular cavity or cleft has been developed in our laboratories at SUNY Stony Brook and the University of Nevada. This approach was initially used to produce torands (e.g., 1, Figure 1) that form exceptionally strong complexes with metal cations.1–11 Butyl substituents, arising from the 9-n-butyloctahydroacridine building block,12 were incorporated into the design of these metal complexing agents in order to enhance their solubilities in organic solvents.
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References
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Bell, T.W., Hou, Z. (1997). Hydrogen Bonding Chemosensors for Metabolites and Nucleotides. In: Desvergne, J.P., Czarnik, A.W. (eds) Chemosensors of Ion and Molecule Recognition. NATO ASI Series, vol 492. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3973-1_9
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