Abstract
Infection is one of the major complications in the use of prosthetic devices. Various Authors investigated the causes which favour such infection. We examined the changes in the resistance to antibiotics after contact with the metals used in the construction of prostheses, under the hypothesis that the persistence of the infection is due to a modification in the sensitivity of microorganisms. Compared with the results obtained from control tests, more or less evident variations of sensitivity to antibiotics were found in some strains which were put in contact with some metals.
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References
Pizzoferrato A., Biomaterials and infection: clinical experience. In Biomaterials and Clinical Applications, ed. A. Pizzoferrato, P.G. Marchetti, A. Ravaglioli and A.J.C. Lee, Elsevier Science Publishers B.V., Amsterdam, 1987, pp. 1–12.
Canner G.C., Steinberg M.E., Heppenstall R.B., Balderston R., The infected hip after total hip arthroplasty. J. Bone Joint Surg., 1984, 66A(9), 1393–1399.
Arciola C., Versura P., Ciapetti G., Monti P., Pizzoferrato A., Caramazza R., Evaluation of adhesion capability of conjunctival Staphylococcus aureus on polymeric materials. In Implant Materials in Biofunction, ed. C. de Putter, G.J. de Lange, K. de Groot and A.J.C. Lee, Elsevier Science Publishers B.V., Amsterdam, 1988, pp. 349–354.
Stea S., Cavedagna D., Pirini W., Arciola C.R., Pizzoferrato A., Interferenza di alcuni biomateriali sulla replicazione batterica “in vitro”. Biomateriali, 1989, 1/2, 11–14.
Nakahara H., Ishikawa T., Sari Y., Kondo I., Frequency of heavy-metal resistance in bacteria from inpatients in Japan. Nature (London), 1977, 266, 165–167.
Smith D.H., R factors mediate resistance to mercury, nickel, and cobalt. Science, 1967, 156, 1114–1116.
Stokes E.J., Clinical Bacteriology. Edward Arnold Publishers, London, 1975, pp.203–225
Gristina A.G., Barth E., Webb L.X., Microbial adhesion and molecular mechanisms in biomaterial and compromised tissue centered infection. In Biomaterials and Clinical Applications, ed. A. Pizzoferrato, P.G. Marchetti, A. Ravaglioli, A.J.C. Lee, Elsevier Science Publishers B.V., Amsterdam, 1987, pp. 661–674.
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© 1991 Elsevier Science Publishers Ltd
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Cenni, E., Savarino, L., Cavedagna, D., Pizzoferrato, A. (1991). Changes of Antibiotic Sensitivity after Contact “In Vitro” of Bacteria with Metals. In: Williams, K.R., Toni, A., Middleton, J., Pallotti, G. (eds) Interfaces in Medicine and Mechanics—2. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3852-9_7
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DOI: https://doi.org/10.1007/978-94-011-3852-9_7
Publisher Name: Springer, Dordrecht
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