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References
Main references
Anderson CC, Gabriel R: Poor hypotensive response and tachyphylaxis following intravenous labetalol. Cur Med Res Opin 5:424, 1978
Homeida M, Jackson L, Roberts CJC: Decreased first-pass metabolism of labetalol in chronic liver disease. Br Med J 2:1048, 1978
Martin LE, Hopkins R, Bland R: Metabolism of labetalol by animals and man. Br J Clin Pharmacol 3 (Suppl 3):695, 1976
McNeil JJ, Anderson AE, Louis WJ: Pharmacokinetics and pharmacodynamic studies of labetalol in hypertensive subjects. Br J Clin Pharmacol 8 (Suppl 2):157S, 1979
McNeil JJ, Louis WJ: Clinical pharmacokinetics of labetolol. Clin Pharmacokinet 9:157, 1984
Williams JG, De Voss K, Craswell PW: Labetalol in the treatment of hypertensive renal patients. Med J Aust 1:225, 1978
Wood AJ, Ferry DG, Bailey RR: Elimination kinetics of labetalol in severe renal failure. Br J Clin Pharmacol 13 (Suppl 1):81S, 1982
Main reference
Dengler HJ, Bodem G, Wirth K: Pharmakokinetische Untersuchungen mit H3-Digoxin und H3-Lanatosid beim Menschen. Arzneimittelforschung (Drug Res) 23:64: 1973
Main references
Aronoff GR, Sloan RS, Luft FC: Pharmacokinetics of moxalactam in patients with normal and impaired renal function. J Infect Dis 145:365, 1981
Aronoff GR, Sloan RS, Mong SA, Luft FC, Kleit SA: Moxalactam pharmacokinetics during hemodialysis. Antimicrob Agents Chemother 19:575, 1981
Donowitz GR, Mandell GL: Beta-lactam antibiotics (Second of two parts). N Engl J Med 318:490, 1988
Hoffman LH: Neurotoxicity associated with moxalactam. Clin Pharm 5:926, 1986
Jacobson EJ, Zahrowski JJ, Nissenson AR: Moxalactam kinetics in hemodialysis. Clin Pharmacol Ther 30:487, 1981
Jones TE, Milne RW, Mudaliar Y, Sansom LN: Moxalactam kinetics during continuous ambulatory peritoneal dialysis after intraperitoneal administration. Antimicrob Agents Chemother 28:293, 1985
Lam M, Manion CV, Czerwinski AW: Pharmacokinetics of moxalactam in patients with renal insufficiency. Antimicrob Agents Chemother 19:461, 1981
Leroy A, Humbert G, Fillastre JP: Pharmacokinetics of moxalactam in subjects with normal and impaired renal function. Antimicrob Agents Chemother 19:965, 1981
Morse GD, Janicke D, Cafarell R, Piontek K, Apicella M, Jusko WJ, Walshe J: Moxalactam epimer disposition in patients undergoing continuous ambulatory peritoneal dialysis. Clin Pharmacol Ther 38:150, 1985
Peterson LR, Bean B, Fasching CE et al.: Pharmacokinetics, protein binding, and predicted extravascular distribution of moxalactam in normal and renal failure subjects. Antimicrob Agents Chemother 20:378, 1981
Singlas E, Boutron HF, Merdjan H, Brocard JF, Pocheville M, Fries D: Moxalactam kinetics during chronic ambulatory peritoneal dialysis. Clin Pharmacol Ther 34:403, 1983
Srinivasan S, Neu HC: Pharmacokinetics of moxalactam in patients with renal failure and during hemodialysis. Antimicrob Agents Chemother 20:398, 1981
Swanson DJ, Reitberg DP, Smit IL, Wels PB, Schentag JJ: Steady state moxalactam pharmacokinetics in patients: Non-compartmental versus two-compartmental analysis. J Pharmacokinet Biopharm 11:337, 1983
Main references
Di Carlo FJ, Leinweber FJ,; Szpiech JM, Davidson IWF: Metabolism of l-bunolol. Clin Pharmacol Ther 22:858, 1977
Leinweber JF, Greenough RC, Di Carlo FJ: Bunolol metabolism by dogs: Identification of basic metabolites and their conjugates. J Pharm Sci 66:1570, 1977
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:790, levobunolol hydrochloride
Main reference
Abrams WB, Coutinho CB, Leon AS, Spiegel HE: Absorption and metabolism of levodopa. JAMA 218:1912, 1971
Akpinar S: Treatment of restless legs syndrome with levodopa plus benserazide. Arch Neurol 39:739, 1982
Cedarbaum JM: Clinical pharmacokinetics of anti-parkinsonian drugs. Clin Pharmacokinet 13:141, 1987
Doller HJ: Levodopa pharmacokinetics. Drug Metab Dispos 6:164, 1978
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1015, levodopa
Nutt JG, Fellman JH: Pharmacokinetics of levodopa. Clin Neuropharmacology 7:35, 1984
Oswald N, Keusch G, Binswanger U: Therapie der urämischen Sympathikopathie mit L-DOPA. Schweiz Med Wochenschr 107:1790, 1977
Sandyk R, Bernick C, Lee SM, Stern LZ, lacono RP, Bamford CR: L-DOPA in uremic patients with the restless legs syndrome. Int J Neurosci 35:233, 1987
von Scheele C: Levodopa in restless legs. Lancet II:426, 1986
Zech P, Collard M, Guey A, Plantier J, Bernard M, Berthoux F, Pinet A, Traeger J: Renal hemodynamic response to L-DOPA during acute renal failure in man. Biomedicine 23:456, 1975
Main references
Beckett GJ, Henderson CJ, Elwes R, Seth J, Lambie AT: Thyroid status in patients with chronic renal failure. Clin Nephrol 19:172, 1983
De Marchi S, Cacchin E: Alterations of circulating thyroid hormone levels in dialysis patients: Another piece to solve the puzzle. Nephron 46:400, 1987
Fish LH, Schwartz HL, Cavanaugh J, Steffes MW, Bantle JP, Oppenheimer JH: Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. N Engl J Med 316:764, 1987
Hoffman AS, Arem R, Eknoyan G: Thyroid function in renal failure. Semin Dialysis 1:154, 1988
Kaptein EM: Thyroid function in renal failure. Contrib Nephrol 50:64, 1986
Kerr DJ, Singh VK, Tsakiris D, McConnell H, Junor BJR, Alexander WD: Serum and peritoneal dialysate thyroid hormone levels in patients on continuous ambulatory peritoneal dialysis. Nephron 43:164, 1986
Lim VS, Zavala DC, Flanigan MJ, Freeman RM: Blunted peripheral tissue responsiveness to thyroid hormone in uremic patients. Kidney Int 31:808, 1987
Löcsey L, Lenkey A, Leövey A: Hormonal changes in haemo-dialysed and in kidney-transplanted patients. Int Urol Nephrol 19:201, 1987
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1488, levothyroxine sodium.
Melmed S, Geola FL, Reed AW, Pekary AE, Park J, Hershman JM: A comparison of methods for assessing thyroid function in nonthyroidal illness. J Clin Endocrinol Metab 54:300, 1982
Pagliacci MC, Pelicci G, Grignani F, Giammartino C, Fedeli L, Carobi C, Buoncristiani U, Nicoletti I: Thyroid function tests in patients undergong maintenance dialysis: Characterization of the ‘Low-T4Syndrome’ in subjects on regular hemodialysis and continuous ambulatory peritoneal dialysis. Neprhon 46:225, 1987
Weissei M, Stummvoll HK, Kovarik J, Zimmermann E, Kaiser F, Fasching I, Puchegger R: Center-specific variations of thyroid hormone serum levels in hemodialysis patients. Nephron 44:212, 1986
Main references
Beckett AH, Boyes RN, Appleton PJ: The metabolism and excretion of lignocaine in man. J Pharm Pharmacol 18 (Suppl):76S, 1966
Benowitz NL, Meister W: Clinical pharmacokinetics of lignocaine. Clin Pharmacokinet 3:177, 1978
Blumer J, Strong JM, Atkinson JR jr: The convulsant potency of lidocaine and its N-dealkylated metabolites. J Pharmacol Exp Ther 186:31, 1973
Boyes RN, Scott DB, Jebson PJ et al.: Pharmacokinetics of lidocaine in man. Clin Pharmacol Ther 12:105, 1971
Breck GD, Trager WF: Oxidative N-dealkylation: A Mannich intermediate in the formation of a new metabolite of lidocaine in man. Science 173:544, 1971
Bromage PR, Gertel M: Brachial plexus anesthesia in chronic renal failure. Anesthesiology 36:488, 1972
Caille G, Lelorier J, Latour Y, Besner JG: GLC determination of lidocaine in human plasma. J Pharm Sci 66:1383, 1977
Collinsworth KA, Strong JM, Atkinson AJ jr, Winkle RA, Perlroth F, Harrison DC: Pharmacokinetics and metabolism of lidocaine in patients with renal failure. Clin Pharmacol Ther 18:59, 1975
DiFazio CA: Biotranformation of lidocaine. Int Anesthesiol Clin 13:21, 1975
Gibson TP, Nelson HA: Drug kinetics and artificial kidneys. Clin Pharmacokinet 2:403, 1977
Grossman SH, Davis D, Kitchell BB, Shand DG, Routledge PA: Diazepam and lidocaine plasma protein binding in renal disease. Clin Pharmacol Ther 31:350, 1982
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1217, lidocaine.
McNamara PJ, Slaughter RL, Pieper JA, Wyman MG, Lalka D: Factors influencing serum protein binding of lidocaine in humans. Anesth Analg 60:395, 1981
Pieper JA Slaughter RL, Anderson GD, Wyman MG, Lalka D: Lidocaine clinical pharmacokinetics. Drug Intell Clin Pharm 16:291, 1982
Rooke NT, Milne B: Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure. Anesth Analg 63:363, 1984
Schuster SB, Kafer ER, Mandel S: Phrenic nerve block associated with interscalene brachial plexus block. Regional Anaesth 8:123, 1983
Strong JM, Mayfield DE, Atkinson AJ jr, Burris BC, Raymon F, Webster LT jr: Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther 17:184, 1975
Tapia L, Cheigh JS, David DS, Sullivan JF, Saal S, Reidenberg MM, Stenzel KH, Rubin AL: Pruritus in dialysis patients treated with parenteral lidocaine. N Engl J Med 296:261, 1977
Thomson PD, Melmon KL, Richardson JA, Cohn K, Steinbrunn W, Cudihee R, Rowland M: Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans. Ann Intern Med 78:499, 1973
Tucker GT, Boyes RN, Bridenbaugh PO, Moore DC: Binding of anilide-type local anesthetics in human plasma. I. Relationships between binding, physiochemical properties, and anesthetic activity. Anesthesiology 33:287, 1970
Tucker GT, Mather LE: Properties, absorption, and disposition of local anesthetic agents. In: Cousins MJ (ed): Neural blockade in clinical anesthesia and management of pain; 2nd ed. Philadelphia: JB Lippincott, 1988 p 47
Vaziri ND, Saiki JK, Hughes W: Clearance of lidocaine by hemodialysis. South Med J 72:1567, 1979
Waller ES: Pharmacokinetic principles of lidocaine dosing in relation to disease state. J Clin Pharmacol 21:181, 1981
Main references
Janssen Pharmaceutica, Beerse (Belgium): Absorption, metabolism and excretion of orally administered lidoflazine in dogs. Biological Research Report R 7904/1, October 1970
Janssen Pharmaceutica, Beerse (Belgium): Absorption, metabolism and excretion of lidoflazine in man. Clinical Progress Report R 7904/15, March 1972
Janssen Pharmaceutica, Beerse (Belgium): The absorption, biotransformation and excretion of lidoflazine in man after a single oral dose of tritium-labelled drug. Clinical Research Report R 7904/83, August 1979
Janssen Pharmaceutica, Beerse (Belgium): The bioavailability of lidoflazine in healthy volunteers after oral administration of the drug at three dose levels (60, 120, 240 mg) and in three dosage forms. Clinical Report R 7904/85, September 1979
Janssen Pharmaceutica, Beerse (Belgium): Steady-state plasma levels of lidoflazine in patients treated with doses of 120 mg t.i.d. Clinical Research Report R 7904/86, October 1979
Janssen Pharmaceutica, Beerse (Belgium): The influence of a meal on the bioavailability of lidoflazine (R 7904) from a 120-mg tablet formulation in healthy volunteers. Clinical Research Report R 7904/87, August 1980
Janssen Pharmaceutica, Beerse (Belgium): Review of the pharmacokinetics and bioavailability of lidoflazine (R 7904) in man. Clinical Report R 7904/95, August 1983
Meuldermans W, Lauwers W, Knaeps A, Heykants J: In vitro metabolism of lidoflazine by rat and dog liver fractions. Arzneimittelforschung (Drug Res) 27(I):828, 1977
Main references
Malacoff RF, Finkelstein FO, Andriole VT: Effect of peritoneal dialysis on serum levels of tobramycin and lincomycin. Antimicrob Agents Chemother 8:574, 1975
Reinarz JA, Mcintosh DA: Lincomycin excretion in patients with normal renal function, severe azotemia and with hemodialysis and peritoneal dialysis. Antimicrob Agents Chemother 5:232, 1965
Main references
Anagostou A, Miller M, Westenfelder C, Clemons G, Baranowski R: Effects of triiodothyronine replacement on the anemia of chronic renal failure. Exp Hematol 16:159, 1988
Beckett GJ, Henderson CJ, Elwes R, Seth J, Lambie AT: Thyroid status in patients with chronic renal failure. Clin Nephrol 19:172, 1983
De Marchi S, Cacchin E: Alterations of circulating thyroid hormone levels in dialysis patients: Another piece to solve the puzzle. Nephron 46:400, 1987
Hoffman AS, Arem R, Eknoyan G: Thyroid function in renal failure. Semin Dialysis 1:154, 1988
Kaptein EM: Thyroid function in renal failure. Contrib Nephrol 50:64, 1986
Kerr DJ, Singh VK, Tsakiris D, McConnell H, Junor BJR, Alexander WD: Serum and peritoneal dialysate thyroid hormone levels in patients on continuous ambulatory peritoneal dialysis. Neprhon 43:164, 1986
Lim VS, Flanigan MJ, Zavala DC, Freeman RM: Protective adaptation of low serum triiodothyronine in patients with chronic renal failure. Kidney Int 28:541, 1985
Lim VS, Zavala DC, Flanigan MJ, Freeman RM: Blunted peripheral tissue responsiveness to thyroid hormone in uremic patients. Kidney Int 31:808, 1987
Löcsey L, Lenkey A, Leövey A: Hormonal changes in haemodialysed and in kidney-transplanted patients. Int Urol Nephrol 19:201. 1987
Melmed S, Geoela FL, Reed AW, Pekary AE, Park J, Hershman JM: A comparison of methods for assessing thyroid function in nonthyroidal illness. J Clin Endocrinol Metab 54:300, 1982
Weissel M, Stummvoll HK, Kovarik J, Zimmermann E, Kaiser F, Fasching I, Puchegger R: Center-specific variations of thyroid hormone serum levels in hemodialysis patients. Nephron 44:212, 1986
Main references
Beermann B: Pharmacokinetics of lisinopril. Am J Med 85 (Suppl 3B):25, 1988
Bussien JP, Waeber B, Nussberger J, Gomez HJ, Brunner HR: Once-daily lisinopril in hypertensive patients effect on blood pressure and the renin-angiotensin system. Curr Ther Res 37:342, 1985
de Jong PE, Apperloo AJ, Heeg JE, de Zeeuw D: Lisinopril in hypertensive patients with renal function impairment. Neprhon 55 (Suppl 1):43, 1990
Gomez HJ, Cirillo VJ, Moncloa F: The clinical pharmacology of lisinopril. J Cardiovasc Pharmacol 9 (Suppl 3):S27, 1987
Lancaster SG, Todd PA: Lisinopril. A preliminary review of the pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure. Drugs 35:646, 1988
Rush JE, Merrill DD: The safety and tolerability of lisinopril in clinical trials. J Cardiovasc Pharmacol 9 (Suppl 3):S99, 1987
Sneddon JM: MK-521, lysine analogue of enalapril. Drugs of the Future 8:925, 1983
Ulm EH, Michens M, Gomez HJ, Till AE, Hand E, Vassil TC, Biollaz J, Brunner HR, Schelling JL: Enalapril maleate and a lysine analogue (MK-521): disposition in man. Br J Clin Pharmacol 14:357, 1982
Main references
Anonymous: Lithium in the management of mania and depression. Drug Ther Bull 8:97, 1970
Batlle D, Gaviria M, Grupp M, Arruda JAL, Wynn J, Kurtzman NA: Distal nephron function in patients receiving chronic lithium therapy. Kidney Int 21:477, 1982
Berens SC, Bernstein RS, Robbins J, Wolff J: Antithyroid effects of lithium. J Clin Invest 49:1357, 1970
Bucht G, Wahlin A, Wentzel T, Winblad B: Renal function and morphology in long-term lithium and combined lithium-neuroleptic treatment. Acta Med Scand 208:381, 1980
Burrows GD, Davies B, Kincaid-Smith P: Unique tubular lesions after lithium. Lancet 1:1310, 1978
Casper RC, Pandey G, Gosenfeld L, Davies JM: Intracellular lithium and clinical response. Lancet II:418, 1976
Depner TA: Nephrotic syndrome secondary to lithium therapy. Nephron 30:286, 1982
Dias N, Hocken AG: Oliguric renal failure complicating lithium carbonate therapy. Nephron 10:246, 1972
Hansen HE, Amdisen A: Lithium intoxication. Quart J Med 47:123, 1978
Harris CA, Jenner FA: The inhibition of the action of vasopressin by lithium ions. J Physiol (Lond) 200:59P, 1969
Hawkins JB, Dorken PR: Lithium. Lancet I:839, 1969
Hestbech J, Hansen HE, Amdisen A, Olsen S: Chronic renal lesions following long-term treatment with lithium. Kidney Int 12:205, 1977
Hestbech J, Aurell M: Lithium induced uremia. Lancet I:212, 1979
Jenner fA, Lee CR: Intracellular lithium and clinical response. Lancet II:641, 1976
Lavender S, Brown JN, Berrill WT: Acute renal failure and lithium intoxication. Postgrad Med J 49:277, 1973
Lee RV, Jampol LM, Brown WV: Nephrogenic diabetes insipidus and lithium intoxication: Complications of lithium carbonate therapy. N Engl J Med 284:93, 1971
Leonhardt KF: Pharmakodynamische Aspekte der Lithiumtherapie. Dtsch Med Wochenschr 99:174, 1974
Lydiard RB, Gelenberg AJ: Hazards and adverse effects of lithium. Annu Rev Med 33:327, 1982
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:365, lithium
Mellerup ET, Gronland H, Plenge P, Raffaelsen OJ: Effect of lithium on carbohydrate metabolism. J Psychosom Res 8:37, 1970
Murphy DL, Goodwin FK, Bunney WE: Aldosterone and sodium response to lithium administration in man. Lancet II:458, 1969
Myers JB, Morgan TO, Carney SL, Ray C: Effects of lithium on the kidney. Kidney Int 18:601, 1980
Peterson B, Shopsin B: Effect of lithium-choloride on the islets of Langerhans in guinea pigs. Acta Endocr (Copenh) 10:731, 1972
Port FK, Kroll PD, Rosenzweig J: Lithium therapy during maintenance hemodialysis. Psychosomatics 20:130, 1977
Procci WR: Mania during maintenance hemodialysis successfully treated with oral lithium carbonate. J Nerv Ment Dis 164:355, 1977
Radomski JL, Fuyat HN, Nelson A, Smith PK: Toxic effects, excretion and distribution of lithium chloride. J Pharmacol 100:429, 1950
Ramsey RA, Mendels J, Stokes JW, Fitzgerald RG: Lithium carbonate and kidney function. A failure in renal concentrating ability. JAMA 219:1446, 1972
Schou M: Lithium studies. I. Toxicity. Acta Pharmacol Toxicol (Copenh) 15:70, 1958
Schou M, Amdisen A, Trap-Jensen J: Lithium poisoning. Am J Psychiatry 125:520, 1968A
Schou M: Special review: Lithium in psychiatric therapy and prophylaxis. J Psychiat Res 6:67, 1968
Schou M: Die Lithium-Prophylaxe bei manisch-depressiven Psychosen. Nervenarzt 42:1, 1971
Scully RE, Galdabini JJ, McNealy BU: Weekly clinicopathological exercises. N Engl J Med 304:1025, 1981
Sedvall G, Johnson B, Petterson U, Levin K: Effects of lithium-salts on plasma-protein bound iodine and uptake of 131I in thyroid gland of man and rat. Life Sci 7:257, 1968
Singer I, Rotenberg D: Mechanism of lithium action. N Engl J Med 289:254, 1973
Thompson K: Serum-lithium determination for clinical use. Scand J Clin Lab Invest 20:104, 1967
Trautner EM, Morris R, Noack CH, Gershon J: The excretion and retention of ingested lithium and its effect on the ionic balance of man. Med J Aust 42:280, 1955
Tupin JP, Schlangenhauf GK, Creson DL: Lithium effects on electrolyte excretion. Am J Psychiatry 125:536, 1968
Walker RG, Bennett WM, Davies BM, Kincaid-Smith P: Structural and functional effects of long-term lithium therapy. Kidney Int 21 (Suppl 11):S13, 1982
Wallin L, Alling C, Aurell M: Impairment of renal function in patients on long-term lithium treatment. Clin Nephrol 18:23, 1982
Main references
Forshell GP, Siwers B, Tuck JR: Pharmacokinetics of lofepramine in man: Relationship to inhibitors of noradrenaline uptake. Eur J Clin Pharmacol 9:291, 1976
Main references
Ellis ME, Weiss RB, Kuperminc M: Nephrotoxicity of lomustine: A case report and literature review. Cancer Chemother Pharmacol 15:174, 1985
Goodman and Gilman’s The pharmacological basis of therapeutics. 7th ed. New York: Macmillan, 1985:1247, chapter 55, Antiproliferative agents and drugs used for immunosuppression by P Calabresi and RE Parks
Harmon WE, Cohen JH, Schneeberger EE, Grupe WE: Chronic renal failure in children treated with methyl CCNU. N Engl J Med 300:1200, 1979
Micetich KC, Jensen-Akula M, Mandard JC et al.: Nephrotoxicity of semustine (methyl-CCNU) in patients with malignant melanoma receiving adjuvant chemotherapy. Am J Med 71:967, 1981
Oliverio VT: Toxicology and pharmacology of the nitrosoureas. Cancer Chemother Rep 4:13, 1973
Schacht RG, Baldwin DS: Chronic interstitial nephritis and renal failure due to nitrosourea (NU) therapy. Kidney Int 14:661, 1978
Silver HKB, Morton DL: CCNU nephrotoxicity following sustained remission in oat cell carcinoma. Cancer Treat Rep 63:226, 1970
Main references General
Huber R: Research Report Byk Gulden, Konstanz (FRG), No. 331/1985
Riedel R: Pharmakologische Eigenschaften von Lonazolac-Ca, einer neuen antiphlogistisch und antirheumatisch wirkenden Substanz. Arzneimittelforschung (Drug Res) 31(I):655, 1981
Renal damage
Abraham PA, Keane WF: Glomerular and interstitial disease induced by nonsteroidal anti-inflammatory drugs. Am J Nephrol 4:1, 1984
Carmichael J, Shankel SW: Effects of non-steroidal anti-inflammatory drugs on prostaglandins and renal function. Am J Med 78:992, 1985
Clive DM, Stoff JS: Renal syndromes associated with nonsteroidal anti-inflammatory drugs. N Engl J Med 310:563, 1984
Duggin GG: Mechanisms in the development of analgesic nephropathy. Kidney Int 18:553, 1980
Dunn MJ: Non-steroidal anti-inflammatory drugs and renal function. Annu Rev Med 35:411, 1984
Hart D, Lifschitz MD: Renal physiology of the prostaglandins and the effects of nonsteroidal anti-inflammatory agents on the kidney. Am J Nephrol 7:408, 1987
Henrich WL: Nephrotoxicity of nonsteroidal anti-inflammatory agents. Am J Kidney Dis 2:478, 1982
Orme ML’E: Non-steroidal anti-inflammatory drugs and the kidney. Br Med J 292:1521, 1986
Reeves WB, Foley RJ, Weinman EJ: Renal dysfunction from nonsteroidal anti-inflammatory drugs. Arch Intern Med 144:1943, 1984
Simon LS, Mills JA: Nonsteroidal antiinflammatory drugs (First of two parts). N Engl J Med 302:1179, 1980
Simon LS, Mills JA: Nonsteroidal antiinflammatory drugs (Second of two parts). N Engl J Med 302:1237, 1980
Torres VE: Present and future of non-steroidal anti-inflammatory drugs in nephrology. Mayo Clin Proc 57:389, 1982
Toto RD, Anderson SA, Brown-Cartwright D, Kokko JP, Brater DG: Effects of acute and chronic dosing of NSAIDs in patients with renal insufficiency. Kidney Int 30:760, 1986
Wegmüller E: Nicht-steroidale Antirheumatika und Nephrotoxizität. Dtsch Med Wochenschr 110:469, 1985
Main references
Heykants JJP, Meuldermans WEG, Knaeps AG, Michiels LJM: The excretion and metabolism of the antidiarrhoeal loperamide in the wistar rat. Eur J Drug Metab Pharmacokinet 2:81, 1977
Shriver AD et al.: Loperamide. In: Goldberg ME (ed.): Pharmacological and biochemical properties of drug substances 3:461, 1981
Van Nueten JM, Janssen PAJ, Fontaine J: Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 3: In vitro studies on the peristaltic reflex and other experiments on isolated tissues. Arzneimittelforschung (Drug Res) 24:1641, 1974
Van Nueten JM, Helsen L, Michiels M, Heykants JJP: Distribution of loperamide in the intestinal wall. Biochem Pharmacol 28:1433, 1979
Weintraub HS, Killinger JM, Keykants J, Kanzler M, Jaff JH: Studies on the elimination rate of loper amide in man after administration of increasing oral doses of Imodium. Curr Ther Res 21:867, 1977
Main references
Illing HP, Bevan CD, Robinson JD, Chamberlain J, Fromson JM: Metabolism of loprazolam in rat, dog and man in vivo. Xenobotica 13:539, 1983
McInnes GT, Bunting EA, Ings RMJ, Robinson J, Ankier SI: Pharmacokinetics and pharmacodynamics following single and repeated nightly administrations of loprazolam, a new benzodiazepine hypnotic. Br J Clin Pharmacol 19:649, 1985
Stevens LA, Bevan CD, Salmon J, Krieger J, Perianu M, LeGo A: Single and repeated dose kinetics of the hypnotic agent loprazolam in healthy volunteers. Eur J Clin Pharmacol 25:651, 1983
Main references
Greenblatt DJ, Divoll M, Harmatz JS, Maclaughlin DS, Shader RI: Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs. Clin Pharmacol Ther 30:475, 1981
Morrison G, Chiang ST, Koepke HH, Walker BR: Effect of renal impairment and hemodialysis on lorazepam kinetics. Clin Pharmacol Ther 35:646, 1984
Verbeeck R, Tjandramaga TB, Verberckmoes R, De Schepper PJ: Biotransformation and excretion of lorazepam in patients with chronic renal failure. Br J Clin Pharmacol 3:1033, 1976
Main references
Amery WK, Heykants JJP, Xhonneux R, Towse G, Oettel P, Gough DA, Janssen PAJ: Lorcainide (R 15889), a first review. Acta Cardiol (Brux) 36:207, 1981
Eiriksson CE, Brogden RN: Lorcainide: A preliminary review of its pharmacodynamic properties and therapeutic efficacy. Drugs 27:279, 1984
Klotz U, Müller-Seydlitz P, Heimburg P: Pharmacokinetics of lorcainide in man: A new antiarrhythmic agent. Clin Pharmacokinet 3:407, 1978
Somani P: Pharmacokinetics of lorcainide, a new antiarrhythmic drug, in patients with cardiac rhythm disorders. Am J Cardiol 48:157, 1981
Somani P, Simon V, Gupta RK, King P, Shapiro RS, Stockard H: Lorcainide kinetics and protein binding in patients with end-stage renal disease. Int J Clin Pharmacol Ther Toxicol 22:121, 1984
Main references
Hümpel M, Illi V, Milius W, Wendt H, Kurowski M: The pharmacokinetics and biotransformation of the new benzodiazepine lormetazepam in humans. I. Absorption, distribution, elimination and metabolism of lormetazepam-5-14C. Eur J Drug Metab Pharmacokinet 4:237, 1979
Hümpel M, IMieuweboer B, Milius W, Hanke H, Wendt H: Kinetics and biotransformation of lormetazepam. II. Radioimmunologic determinations in plasma and urine of young and elderly subjects: First-pass effect. Clin Pharmacol Ther 28:673, 1980
Kampf D, Hümpel M, Lerche U, Kessel M: Effects of uremia and hemodialysis on lormetazepam disposition. Clin Pharmacol Ther 30:77, 1981
Main references
Tobert JA: New developments in lipid-lowering therapy: The role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase. Circulation 76:534, 1987
Vega GL, Grundy SM: Lovastatin therapy in nephrotic hyperlipidemia: Effects on lipoprotein metabolism. Kidney Int 33:1160, 1988
Main reference
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:749, loxapine
Main reference
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1144, luteinising hormone
Main reference
Hümpel M, Wendt H, Dogs G, Weiß C, Rietz S, Speck U: Intraindividual comparison of pharmacokinetic parameters of d-norgestrel, lynestrenol and cyproterone acetate in 6 women. Contraception 16:199, 1977
Main reference
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1137, lypressin
Main reference
Martindale. The extra pharmacopoeia. 29th ed. London: The Pharmaceutical Press, 1989:1584, lysergide.
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Seyffart, G. (1991). L. In: Drug Dosage in Renal Insufficiency. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3804-8_12
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