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Protein adsorption and the interaction of human endothelial cells with polymer surfaces

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Book cover Modern Aspects of Protein Adsorption on Biomaterials

Abstract

A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of improved small-diameter vascular grafts. HEC, suspended in culture medium containing 20% human serum adhere and spread on moderately water-wettable polymers (contact angle of about 40 degrees, Ref. 1). Examples of such polymers are: tissue culture polystyrene (TCPS), tissue culture poly(ethylene terephthalate) (TCPETP), cellulose-3-acetate, and a copolymer of hydroxy-ethyl methacrylate (HEMA) and methyl methacrylate (MMA), mol ratio 25 HEMA/75 MMA.

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References

  1. Van Wachem, P.B., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J.P., Van Aken, W.G., ‘Interactions of cultured human endothelial cells with polymeric surfaces of different wettabilities’, Biomaterials 1985, 6, 403–408.

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© 1991 Springer Science+Business Media Dordrecht

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Dekker, A., Beugeling, T. (1991). Protein adsorption and the interaction of human endothelial cells with polymer surfaces. In: Missirlis, Y.F., Lemm, W. (eds) Modern Aspects of Protein Adsorption on Biomaterials. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3752-2_3

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  • DOI: https://doi.org/10.1007/978-94-011-3752-2_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5669-4

  • Online ISBN: 978-94-011-3752-2

  • eBook Packages: Springer Book Archive

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