Abstract
A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of improved small-diameter vascular grafts. HEC, suspended in culture medium containing 20% human serum adhere and spread on moderately water-wettable polymers (contact angle of about 40 degrees, Ref. 1). Examples of such polymers are: tissue culture polystyrene (TCPS), tissue culture poly(ethylene terephthalate) (TCPETP), cellulose-3-acetate, and a copolymer of hydroxy-ethyl methacrylate (HEMA) and methyl methacrylate (MMA), mol ratio 25 HEMA/75 MMA.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Van Wachem, P.B., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J.P., Van Aken, W.G., ‘Interactions of cultured human endothelial cells with polymeric surfaces of different wettabilities’, Biomaterials 1985, 6, 403–408.
Van Wachem, P.B., ‘Interactions of cultured human endothelial cells with polymeric surfaces’, Ph.D. Thesis, University of Twente, 1987.
Van Wachem, P.B., Hogt, A.H., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J.P., Van Aken, W.G., ‘Adhesion of cultured human endothelial cells onto methacrylate polymers with varying surface wettability and charge’, Biomaterials 1987, 8, 323–328.
Van Wachem, P.B., Mallens, B.W.L., Dekker, A., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J.P., Van Aken, W.G., ‘Adsorption of fibronectin derived from serum and from human endothelial cells onto tissue culture polystyrene’, J. Biomed. Mater. Res. 1987, 21, 1317–1327.
Van Wachem, P.B., Beugeling, T., Mallens, B.W.L., Dekker, A., Feijen, J., Bantjes, A., Van Aken, W.G., ‘Deposition of endothelial fibronectin on polymeric surfaces’, Biomaterials 1988, 9, 121–123.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Dekker, A., Beugeling, T. (1991). Protein adsorption and the interaction of human endothelial cells with polymer surfaces. In: Missirlis, Y.F., Lemm, W. (eds) Modern Aspects of Protein Adsorption on Biomaterials. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3752-2_3
Download citation
DOI: https://doi.org/10.1007/978-94-011-3752-2_3
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-5669-4
Online ISBN: 978-94-011-3752-2
eBook Packages: Springer Book Archive