Abstract
Since 1957, over 156 cases of Landau and Kleffner syndrome have been published. As yet, nevertheless, no general overview of the syndrome’s natural history has been written. This is partly because of methodological difficulties that arise, and which are discussed. Our experience includes among 18 cases of Landau and Kleffner syndrome 12 subjects followed at least until the age of fourteen and during at least seven years. Among these, none have completely recovered; the evolution was very unfavourable in one case. In seven cases it was unfavourable and in four mild sequels were noted (favourable evolution). The role of the age at onset of the language disorders and of the duration of follow-up, the interest of sleep EEG are discussed. This clinical experience shows that the pattern of evolution of Landau and Kleffner syndrome may not be as heterogeneous as has been supposed.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ansink, B.J.J., Sarphatie, H., Van Dongen, H.R. (1989)’The Landau-Kleffner syndrome — Case report and theoretical considerations’, Neuropediatrics 20, pp. 170–172.
Bishop, D.V.M., (1985)’Age of onset and outcome in “acquired aphasia with convulsive disorder’ (Landau-Kleffner syndrome). Dev. Med. Child. Neurol. 27, pp. 705–712.
Beaumanoir, A. (1984)’Le syndrome de Landau-Kleffner. In “Les syndromes épileptiques de l’enfant et de l’adolescent’. Paris: John Libbey, pp. 185–195.
Billard, C., Autret, A., Laffont, F., De Giovanni, E., Lucan, B., Dulac, O., Plouin, P. (1981)’Aphasie acquise de l’enfant avec épilepsie. A propos de 4 observations avec état de mal électrique infraclinique du sommeil’ Rev. E.E.G. Neurophysiol. 11, pp. 457–467.
Brissaud, H.E., Richardet, J.M. (1974)’Le syndrome de désintégration du langage et comitialité’ Journées Parisiennes de Pédiatric, pp. 441–445.
Buchman, A.S., Garron, D.C., Trost Cardamone, J.E., Witcher, M.D., Schwartz, M. (1986)’Word deafness: one hundred years later’ J. Neurol. Neurosurg. Psychiat. 49, pp. 489–499.
Cole, A.J., Andermann, F., Taylor, L., Olivier, A., Rasmussen, T., Robitaille, Y., Spire, J.P. (1988)’The Landau-Kleffner syndrome of acquired epileptic aphasia: unusual clinical outcome, surgical experience and absence of encephalitis’ Neurology 38, pp. 31–38.
Deonna, T., Beaumanoir, A., Gaillard, F., Assal, G. (1977)’Acquired aphasia in childhood with seizure disorder: a heterogeneous syndrome’ Neuropädiatrie 8, pp. 263–273.
Deonna, T., Peter, C., Ziegler, A.L. (1989)’Adult follow-up of the acquired aphasia-epilepsy syndrome in childhood. Report of 7 cases’ Neuropediatrics, 20, pp. 132–138.
Dugas, M., Grenet, P., Masson, M., Mialet, J.P., Jaquet, G. (1976) ‘Aphasie de l’enfant avec épilepsie. Evolution régressive sous traitement anti-épileptique’ Rev. Neurol. (Paris) 132, pp. 489–493.
Dugas, M., Masson, M., Le Heuzey, M.F., Regnier, M. (1982)’Aphasie “acquise” de l’enfant avec épilepsie (syndrome de Landau et Kleffner). Douze observations personnelles’ Rev. Neurol. (Paris) 138, pp. 755–780.
Dulac, O., Billard, C., Arthuis, M. (1983)’Aspects électro-cliniques et évolutifs de l’épilepsie dans le syndrome aphasie-épilepsie’ Arch. Fr. Pediatr. 40, pp. 299–308.
Gascon, G., Victor, D., Lombroso, C.T., Goodglass, H. (1973)’Language disorder, convulsive disorder and electroencephalographic abnormalities’ Arch. Neurol. 28, pp. 156–162.
Gastaut, H., Roger, J., Soulayrol, R., Tassinari, C., Régis, H., Dravet, C., Bernard, R., Pinsard, N., Saint-Jean, M. (1966)’Childhood epileptic encephalopathy with diffuse slow spike-waves (otherwise known as ‘petit mal variant’) or Lennox syndrome’ Epilepsia 7, pp. 139–179.
Holmes, G., Mc Keever, M, Saunders, Z. (1981)’Epileptiform activity in aphasia in childhood: an epiphenomenous?’ Epilepsia 22, pp. 631–639.
Landau, W.M. and Kleffner, F.R. (1957)’Syndrome of acquired aphasia with convulsive disorder in children’. Neurology 7, PP. 523–530.
Lankriet, C. (1980)’Syndrome de Landau et Kleffner, désintégration du langge et comitialité’ Thèse Médecine, Lille. (FRANCE)
Lou, H.C., Brandt, D., Bruhn, P. (1977)’Aphasia and epilepsy in childhood’. Acta Neurol. Scand. 56, pp. 46–54.
Mantovani, J.F., Landau, W.M. (1980)’Acquired aphasia with convulsive disorder: course and prognosis’ Neurology 30, pp. 524–529.
Méndez, M.F. and Geehan, G.R. (1988)’Cortical auditory disorders: clinical and psychoacoustic features’ J. Neurol. Neurosurg. Psychiat. 51, pp. 1–9.
Nakano, S., Okuno, T., Mikawa, H. (1989)’Landau-Kleffner Syndrome EEG topographic studies’ Brain and Development, 11, pp. 43–50.
Noel, A. (1980) ‘Le syndrome de Landau-Kleffner’ Revue de littérature à propos de quatre observations personnelles. Thèse Médecine, Lyon.
Picard, A., Dulac, O., Billard, C., Raynaud, C., Lacert, P. (in press)’Aphasie acquise avec épilepsie: syndrome de Landau-Kleffner (évolution à long terme et suivi de deux observations sur neuf et huit ans)’. Rev. Neurol. (Paris).
Satz, P. (1990)’Developmental dyslexia: an etiological reformulation. In Pavlidis, G.T. (ed.): Perspectives on dyslexia. Vol. 1, New-York: John Wiley and Sons, pp. 3–26.
Shoumaker, R.D., Bennett, D.R., Bray, P.F., Curless, R.G. (1974)’Clinical and EEG manifestations of an unusual aphasic syndrome in children’ Neurology 24, pp. 10–16.
Stein, L.K., Curry, F.K.W. (1968) ’Childhood auditory agnosia’ J. Speech Hear. Disord. 33, pp. 361–370.
Toso, V., Moschini, M., Gagnin, G., Antoni, D. (1981)’Aphasie acquise de l’enfant avec épilepsie. Trois observations et revue de la littérature’. Rev. Neurol. (Paris) 137, pp. 425–434.
Van Dongen, H.R., Meulstee, J., Blaw-Van-Mourik, M., Van Harskamp, F. (1989)’Landau-Kleffner syndrome: a case study with a fourteen-year follow-up’ Eur. Neurol. 29, pp. 109–114.
Vidailhet, C., Debruille, C., Hentz, P., Tridon, P. (1983)’A propos du syndrome de Landau-Kleffner. Aphasie acquise-épilepsie chez l’enfant’ Rev. Otoneuroophtalmol. 55, pp. 215–219.
Worster-Drought, C. (1971)’An unusual form of acquired aphasia in children’ Dev. Med. Child. Neurol. 13, pp. 563–571.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Dugas, M., Gerard, C.L., Franc, S., Sagar, D. (1991). Natural History, Course and Prognosis of the Landau and Kleffner Syndrome. In: Martins, I.P., Castro-Caldas, A., van Dongen, H.R., van Hout, A. (eds) Acquired Aphasia in Children. NATO ASI Series, vol 60. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3582-5_22
Download citation
DOI: https://doi.org/10.1007/978-94-011-3582-5_22
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-5588-8
Online ISBN: 978-94-011-3582-5
eBook Packages: Springer Book Archive