Cultivation of Hepatocytes in a New Entrapment Reactor: a Potential Bioartificial Liver
Liver failure is a major cause of mortality.1 Most patients admitted to an intensive care unit in liver failure do not survive. Currently, the only available treatment for refractory liver failure is hepatic transplantation. Renal dialysis, which revolutionized the treatment of renal failure, does not have a hepatic equivalent. There is a critical demand to develop an artificial liver for short-term support of hepatic failure. Given the functional complexity of the liver, the most promising approach to the development of an artificial liver involves using cultivated hepatocytes to supply function.
KeywordsHigh Performance Liquid Chromatography Hollow Fiber High Performance Liquid Chromatography Analysis Hollow Fiber Membrane Unconjugated Bilirubin
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