Recent Advances in Animal Cell Biotechnology

  • R. E. Spier


It is generally agreed that from the the products of the new biotechnology, (that involving genetic engineering and/or cell fusion), the value of products made from animal cells in culture accounts for about half of the total revenue which accrues to all the new biotechnology products. (Table 1).


Animal Cell Oxygen Transfer Oxygen Transfer Rate Animal Cell Culture Biotechnology Product 
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  1. 1.
    R.E. Spier, 1990 Introduction to Volume 4; Contemporary Issues in Animal Cell Biotechnology. In Animal Cell Biotechnology Volume 4, Ed. R.E. Spier and J.B. Griffiths Academic Press, London, pp 1–13Google Scholar
  2. 2.
    R.E. Spier and N. Maroudas, (1991) Microcarriers for Animal Cell Biotechnology:An Unfulfilled Potential In Animal Cell Bioreactors, Ed C. Ho and D. Wang Butterworh-Heinemann, Guildford.Google Scholar
  3. 3.
    R.E. Spier, (1989) Animal Cell Culture: From Obscurity to Prominence to…. In the Proceedings of the Eighth australian Biotechnology Conference University of New South Wales pp 41–51.Google Scholar
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    R.E. Spier, 1991 Animal Cells Make Secondary Metabolites Too In Production of Biologicals from Animal Cells in Culture Ed. R.E. Spier, J.B. Griffiths, B. Meignier Butterworths, LondonGoogle Scholar
  5. 5.
    R.E. Spier, 1991 Meeting Report in Vaccine To be published.Google Scholar
  6. 6.
    R.E. Spier, 1990 Editorial in Enzyme and Microbial Technology, EMT v.12, 562–3PubMedGoogle Scholar
  7. 7.
    R.E. Spier and J.B. Griffiths, (1983) An Examination of the Data and Concepts germane to the Oxygenation of Cultured Animal Cells Dev. Biol. Standard. v. 55 pp 81–92Google Scholar
  8. 8.
    A. Handa-Corrigan, N. Emery and R.E. Spier (1989) Effect of gas -liquid interfaces on the growth of suspended mammalian cells: mechanisms of cell damage by bubbles. Enzyme and Microbial Tech. Vol 11., No. 4. pp 230–235.CrossRefGoogle Scholar
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    R.E. Spier, (1990) The Oxygenation of Animal Cell Cultures by Bubbles In Animal Cell Biotechnology volume 4 Ed. R.E. Spier and J.B. Griffiths Academic, London, pp 134–149.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • R. E. Spier
    • 1
  1. 1.Wolfson Cytotechnology Laboratory, School of Biological SciencesUniversity of SurreyGuildford, SurreyUK

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