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Formation of Multicellular Aggregates of Adult Rat Hepatocytes

  • Yasuyuki Sakai
  • Motoyuki Suzuki

Abstract

Since hepatocytes in primary culture express various differentiated hepatic functions in vitro for a certain period of time, large scale culture of the cells with high density are expected to have many important applications. Particularly, a hybrid artificial liver using normal hepatocytes is expected for an effective treatment of acute hepatic failure.

Keywords

Hepatic Function Large Scale Culture Spheroid Formation Acute Hepatic Failure Urea Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • Yasuyuki Sakai
    • 1
  • Motoyuki Suzuki
    • 1
  1. 1.Institute of Industrial ScienceUniversity of TokyoMinato-ku, TokyoJapan

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