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Prevention of occult atherosclerotic disease

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Occult Atherosclerotic Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 123))

Abstract

The twentieth century has seen an epidemic of cardiovascular disease, much of which is due to atherosclerosis. The major cause of death has become coronary heart disease and cerebral vascular disease [1]. Although atherosclerosis was known in early 1900s it has risen in proportion to other causes of death, especially infectious disease which has declined greatly with the advent of effective therapy. The increase in the incidence of atherosclerosis also parallels the increasing age of the population. In general, there is a correlation between atherosclerosis in one arterial system and atherosclerosis elsewhere in the body [2] (see chapters 7 and 22). For instance, the main cause of death for persons with carotid artery disease is coronary disease [3]. Many patients with abdominal aortic aneurysm have significant coronary disease [4, 5]. Most of what has been written concerning the prevention of atherosclerotic disease has dealt with coronary disease as the prime example. Therefore, in this chapter we will use the information available on coronary disease, highlighting information pertaining to specific other vascular trees when such is available. For this discussion we will not differentiate between occult and clinically apparent atherosclerotic disease since the principles of prevention are the same.

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References

  1. Heart Facts. Dallas Texas, American Heart Association, 1983.

    Google Scholar 

  2. Taylor P C. Evaluation and surgical management of patients with severe combined coronary artery disease and peripheral vascular atheroschlerosis. Clev Clin Quart 1981; 48:172.

    CAS  Google Scholar 

  3. Newman D C, Hicks R C. Combined carotid and coronary artery surgery; a review of the literature. Ann Thoracic Surgery 1988; 45:574.

    Article  CAS  Google Scholar 

  4. Brown O W, Hollier L H, Pairolero P C et al. Abdominal aortic aneurysm and coronary artery disease: A reassessment. Arch Surg 1981; 116:1484.

    Article  PubMed  CAS  Google Scholar 

  5. Roger V L, Ballard D J, Hallett J W Jr et al. Influence of coronary disease on morbidity and mortality after abdominal aortic aneurysmectomy: A population based study 1971-1987. JACC 1989; 14:1245.

    PubMed  CAS  Google Scholar 

  6. Holme I, Solberg L A, Weissfeld L et al. Coronary risk factors and their pathway of action through coronary raised lesions, coronary stenoses and coronary death: Multivariate Statistical analysis of an autopsy series: The Oslo study. Am J Cardiol 1985; 55:40.

    Article  PubMed  CAS  Google Scholar 

  7. Ross R. The pathogenesis of atheroschlerosis — an update. N Engl J Med 1986; 314:488.

    Article  PubMed  CAS  Google Scholar 

  8. Castelli W P. Epidemiology of coronary heart disease: The Framingham Study. Am J Med 1984; 76, 2A:4.

    Article  PubMed  CAS  Google Scholar 

  9. Coronary Risk Handbook. Estimating risk of coronary heart disease in daily practice, Dallas TX, American Heart Association, 1973.

    Google Scholar 

  10. Watkins L O. Why are death rates from coronary heart disease decreasing? Which preventive measures are effective? Postgraduate Medicine 1984; 75:201.

    PubMed  CAS  Google Scholar 

  11. Gillium R F, Folsom A R, Blackburn H. Decline in coronary heart disease mortality. Am J Med 1984; 76:1055.

    Article  Google Scholar 

  12. Goldman L, Cook E F. The decline in ischaemic heart disease mortality rates: an analysis of the comparative effects of medical interventions and changes in lifestyle. Ann Intern Med 1984; 101:825.

    PubMed  CAS  Google Scholar 

  13. Matthews K A, Meilahn E, Kuller L H et al. Menopause and risk factors for coronary heart disease. N Engl J Med 1989; 321:641.

    Article  PubMed  CAS  Google Scholar 

  14. Barrett-Conner E, Khaw K. Family history of heart attack as an independent predictor of death due to cardiovascular disease. Circulation 1984; 69:1065.

    Article  Google Scholar 

  15. Fielding J E. Smoking: Health effects and control. N Engl J Med 1985; 313:491.

    Article  PubMed  CAS  Google Scholar 

  16. Abbott R D, Yin Y, Reed D M et al. Risk of stroke in male cigarette smokers. N Engl J Med 1986; 315:717.

    Article  PubMed  CAS  Google Scholar 

  17. Kannel W B. Cigarette smoking in peripheral arterial disease. Primary Cardiology, March, 1986; 13.

    Google Scholar 

  18. Stamler J, Stamler R. Intervention for the prevention and control of hypertension and atherosclerotic diseases: United States and international experience. Am J Med 1984; 76 2A:13.

    Article  Google Scholar 

  19. Salonen J T. Stopping smoking and long term mortality after acute myocardial infarction. Br Heart J 1980; 43:463.

    Article  PubMed  CAS  Google Scholar 

  20. Cummings S R, Coates T J, Richard R J et al. Training physicians in counselling about smoking cessation. A randomized trial of the ‘quit for life’ program. Ann Intern Med 1989; 110:640.

    PubMed  CAS  Google Scholar 

  21. Gordon T, Kannel W B. Predisposition to atherosclerosis in the head, heart and lungs: The Framingham study. JAMA 1972; 221:661.

    Article  PubMed  CAS  Google Scholar 

  22. Veterans Administration Cooperative Study Group on antihypertensive agents. Effects of treatment on morbidity in hypertension — results in patients with diastolic blood pressures averaging 115 through 129 mmHg. JAMA 1967; 213:1143.

    Google Scholar 

  23. Grimm R H Jr. Should mild hypertension be treated? Early intervention. Medical Clinics of North America 1984; 68:477.

    PubMed  Google Scholar 

  24. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of Hypertension Detection and Follow-up Program. JAMA 1979; 242:2562.

    Article  Google Scholar 

  25. Medical Research Council Working Party on Mild Hypertension. Coronary heart disease in the medical research council trial of treatment of mild hypertension. Br Heart J 1988; 59:364.

    Article  Google Scholar 

  26. Amery A, Brixko P, Clement D et al. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly Trial. Lancet 1985; 1:1349.

    Article  PubMed  CAS  Google Scholar 

  27. Kannel W B, Dawber T R, McGee D L. Perspectives on systolic hypertension: The Framingham Study. Circulation 1980; 61:1179.

    Article  PubMed  CAS  Google Scholar 

  28. Hulley S B, Furberg C D, Gurland B et al. Systolic Hypertension in Elderly Program (SHEP), anti-hypertensive effect of chlorthalidone. Am J Cardiol 1985; 56:913.

    Article  PubMed  CAS  Google Scholar 

  29. Frohlich E D. Cardiac hypertrophy in hypertension. N Engl J Med 1987; 317:831.

    Article  PubMed  CAS  Google Scholar 

  30. The Expert Panel. Report of the National Cholesterol Education Program Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults. Arch Intern Med 1988; 148:36.

    Article  Google Scholar 

  31. Walker W J. Changing U.S. lifestyle and declining vascular mortality: A retrospective (Editorial). N Engl J Med 1983; 308:649.

    Article  PubMed  CAS  Google Scholar 

  32. Abraham S, Rifkind B M, Feinleib M et al. Decline in serum cholesterol levels among adults in the United States, (abstract) Circulation 1983; 68:111–179.

    Google Scholar 

  33. Multiple Risk Factor Intervention Group. Multiple Risk Factor Intervention Trial. Risk factor changes and mortality results. JAMA 1982; 248:1465.

    Article  Google Scholar 

  34. Oliver M F, Heady J A, Morris J N et al. A cooperative trial in the primary prevention of ischemic heart disease using Clofibrate: Report from the Committee of Principal Investigators. Br Heart J 1978; 40:1069.

    Article  Google Scholar 

  35. Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results. Reduction in incidence of coronary heart disease. JAMA 1984; 251:351.

    Article  Google Scholar 

  36. Frick M H, Elo O, Haapa K et al. Helsinki Heart Study: Primary prevention trial with gemfibrozil in middle aged men with dyslipidemia. N Engl J Med 1987; 317:1237.

    Article  PubMed  CAS  Google Scholar 

  37. Weissler A M, Miller B I, Boudoulas H. The need for clarification of percent risk reduction data in clinical cardiovascular trial reports. JACC 1989; 13:764.

    PubMed  CAS  Google Scholar 

  38. Oliver M F. Cousensus or nonsensus conference on coronary heart disease. Lancet 1985; 2:1087.

    Article  Google Scholar 

  39. Palumbo P J. National Cholesterol Education Program. Does the emperor have any clothes? (Editorial) Mayo Clin Proc 1988; 63:88.

    Article  PubMed  CAS  Google Scholar 

  40. Corday E, Ryden L. Why some physicians have concerns about the cholesterol awareness program. JACC 1989; 13:497.

    PubMed  CAS  Google Scholar 

  41. Garber A M. Where to draw the line against cholesterol (editorial) Ann Intern Med 1989; 111:625.

    PubMed  CAS  Google Scholar 

  42. Basinski A, Frank J W, Naylor C D et al. Detection and management of asymptomatic hypercholesterolemia. A policy document by the Toronto Working Group on Cholesterol Policy. Toronto, Ontario Ministry of Health, 1989.

    Google Scholar 

  43. Iso H, Jacobs D R Jr, Wentworth D et al. Serum cholesterol levels and six-year mortality from stroke in 350, 977 men screened for the Multiple Risk Factor Intervention Trial. N Engl J Med 1989; 320:904.

    Article  PubMed  CAS  Google Scholar 

  44. Barr D P, Russ E M, Eder H A. Protein lipid relationship in human plasma II. In atherosclerosis and related conditions. Am J Med 1951; 11:480.

    Article  PubMed  CAS  Google Scholar 

  45. Ginsburg G S, Safran C, Pasternak R C. National Cholesterol Education Program guidelines: The impact of missing HDL. Circulation (abstract) 1988; 78:11 382.

    Google Scholar 

  46. Castell, W P, Garrison R J, Wilson P W F et al. Incidence of coronary heart disease and lipoprotein cholesterol levels: The Framingham Study. JAMA 1986; 256:2835.

    Article  Google Scholar 

  47. Buchwald H, Varco R L, Matts et al. Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolaemia. Report of the program on surgical control of hyperlipidaemia (POSCH). N. Engl. J. Med. 1990; 323:947.

    Article  Google Scholar 

  48. Ballard-Barbash R, Callaway CW. Marine fish oils: role in prevention of coronary artery disease. Mayo Clin Proc 1987; 62:113.

    Article  PubMed  CAS  Google Scholar 

  49. Bak A A A, Grobbee D E. The effect on serum cholesterol levels of coffee brewed by filtering or boiling. N Engl J Med 1989; 321:1432.

    Article  PubMed  CAS  Google Scholar 

  50. Vermaak W J H. Variability in plasma cholesterol essays. The object that defects the goal (letter) Am J Cardiol 1988; 62:841.

    Article  PubMed  CAS  Google Scholar 

  51. West K M. Epidemiology of diabetes and its vascular complications. Elsevier, New York: 1978.

    Google Scholar 

  52. Kroc Collaborative Study Group. Blood glucose control and the evolution of diabetic retinopathy and albuminuria. N Engl J Med 1984; 311:365.

    Article  Google Scholar 

  53. Powell K E, Thompson P D, Caspersen C J et al. Physical activity and the incidence of coronary heart disease. Ann Rev Public Health 1987; 8:253.

    Article  CAS  Google Scholar 

  54. Paffenbarger R S, Hyde R T, Wing A L et al. Physical activity, all cause mortality and longevity of college alumni. N Engl J Med 1986; 314:605.

    Article  PubMed  Google Scholar 

  55. Kramsch D M, Aspen A J, Abramowitz B M et al. Reduction of coronary atherosclerosis by moderate conditioning exercise in monkeys on an atherogenic diet. N Engl J Med 1981; 305:1483.

    Article  PubMed  CAS  Google Scholar 

  56. Hubert H B, Feinleib M, McNamara P M et al. Obesity as an independent risk factor for cardiovascular disease: A 26 year follow-up of participants in the Framingham Heart Study. Circulation 1983; 67:968.

    Article  PubMed  CAS  Google Scholar 

  57. Larsson B, Svardsudd K, Welin L et al. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men form in 1913. Br Med J 1984; 288:1401.

    Article  CAS  Google Scholar 

  58. Friedman M, Rosenman R H. Type A behavior and your heart. New York, Alfred A Knopf, 1974.

    Google Scholar 

  59. Ragland D R, Brand R J. Type A behavior and mortality from coronary heart disease. N Engl J Med 1988; 318:65.

    Article  PubMed  CAS  Google Scholar 

  60. Dimsdale J E. A perspective of Type A behavior and coronary disease (editorial) N Engl J Med 1988; 318:110.

    Article  PubMed  CAS  Google Scholar 

  61. Williams R B Jr. Refining the Type A hypothesis: emergence of the hostility complex. Am J Cardiol 1987; 60:273.

    Article  Google Scholar 

  62. Steering Committee of the Physicians Health Study Research Group. Final report on the aspirin component of the ongoing Physicians Health Study. N Engl J Med 1989; 321:129

    Article  Google Scholar 

  63. Klint C R, Knatterud G L, Stamler J et al. Persantine-Aspirin Reinfarction Study Part II. Secondary coronary prevention with persantine and aspirin. JACC 1986; 7:251.

    Google Scholar 

  64. Harker L A. Clinical trials evaluating platelet modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. Circulation 1986; 73:206.

    Article  PubMed  CAS  Google Scholar 

  65. Miettinen T A, Huttunen J K, Naukkarinen V et al. Multifactorial primary prevention of cardiovascular diseases in middle aged men. JAMA 1985; 254:2097.

    Article  PubMed  CAS  Google Scholar 

  66. Hjermann I, Velve B K, Holme I et al. Effect of diet and smoking intervention of the incidence of coronary heart disease. Report from the Oslo Study Group of a randomized trial in healthy men. Lancet 1981; 2:1303.

    Article  PubMed  CAS  Google Scholar 

  67. Kornitzer M, Dramaix M, Thilly C et al. Belgian Heart Disease Prevention Project: Incidence and mortality results. Lancet 1983; 1:1066.

    Article  PubMed  CAS  Google Scholar 

  68. Research Group of the Rome Project of Coronary Heart Disease Prevention. Eight year follow-up results from the Rome Project of Coronary Heart Disease Prevention. Prev Med 1986; 15:176.

    Article  Google Scholar 

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Authors
  1. Brent M. Parker
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  2. Vaskar Mukerji
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Editor information

Editors and Affiliations

  1. Department of Cardiology, Central Middlesex Hospital, London, UK

    Abdul-Majeed Salmasi

  2. Irvine Laboratory for Cardiovascular Investigation and Research, St. Mary’s Hospital, London, UK

    Andrew N. Nicolaides

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© 1991 Springer Science+Business Media Dordrecht

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Parker, B.M., Mukerji, V. (1991). Prevention of occult atherosclerotic disease. In: Salmasi, AM., Nicolaides, A.N. (eds) Occult Atherosclerotic Disease. Developments in Cardiovascular Medicine, vol 123. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3404-0_24

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  • DOI: https://doi.org/10.1007/978-94-011-3404-0_24

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5506-2

  • Online ISBN: 978-94-011-3404-0

  • eBook Packages: Springer Book Archive

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