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Transplantation for hepatobiliary malignancies

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Organ Transplantation 1990

Part of the book series: Developments in Surgery ((DISU,volume 11))

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Abstract

The use of liver transplantation in the treatment of hepatobiliary malignancies remains controversial. In the early experience with liver transplantation, patients with hepatobiliary maligancies were considered the ideal candidates for transplantation because, in most cases, they had not experienced the sequelae of chronic end stage liver disease. The operative procedure was straightforward and the early success rates were better than for any other group of patients. However, with longer follow-up an extremely high recurrences rate for these tumors (> 80% at 2 years) led a number of transplant centers to abandon the use of transplantation for the treatment of patients with hepatobiliary malignancies. This review will briefly discuss the results of liver transplantation for hepatobiliary malignancies and outline the potential future applications of this therapy. The experience from several centers will be reviewed. The overall actuarial survival for all types of malignancies ranges from 20 to 40% at 3 years in these series (1–5).

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Authors
  1. R. Patrick Wood
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  2. Byers W. Shaw Jr.
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  3. Robert J. Stratta
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  4. Alan N. Langnas
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  5. Todd J. Pillen
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Editor information

Editors and Affiliations

  1. Division of Transplantation, Hahnemann University, Philadelphia, Pennsylvania, USA

    G. M. Abouna M.D., F.R.C.S., (C), F.A.C.S. (Prof. of Surgery, Director, former Professor and Chairman) (Prof. of Surgery, Director, former Professor and Chairman)

  2. Department of Organ Transplantation, Kuwait University and Hamed Al-Essa Organ Transplant Center, Kuwait City, Kuwait

    G. M. Abouna M.D., F.R.C.S., (C), F.A.C.S. (Prof. of Surgery, Director, former Professor and Chairman) (Prof. of Surgery, Director, former Professor and Chairman)

  3. Department of Surgery, Hahnemann University, Philadelphia, Pennsylvania, USA

    M. S. A. Kumar M.D., F.R.C.S.E. (Assistant Professor, Former Associate Professor) (Assistant Professor, Former Associate Professor)

  4. Department of Organ Transplantation, Kuwait University, Kuwait City, Kuwait

    M. S. A. Kumar M.D., F.R.C.S.E. (Assistant Professor, Former Associate Professor) (Assistant Professor, Former Associate Professor)

  5. Department of Organ Transplantation, Kuwait University and Hamad Al-Essa Transplant Center, Kuwait City, Kuwait

    A. G. White Ph.D. (Assistant Professor) (Assistant Professor)

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© 1991 Springer Science+Business Media Dordrecht

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Wood, R.P., Shaw, B.W., Stratta, R.J., Langnas, A.N., Pillen, T.J. (1991). Transplantation for hepatobiliary malignancies. In: Abouna, G.M., Kumar, M.S.A., White, A.G. (eds) Organ Transplantation 1990. Developments in Surgery, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3386-9_39

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  • DOI: https://doi.org/10.1007/978-94-011-3386-9_39

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5497-3

  • Online ISBN: 978-94-011-3386-9

  • eBook Packages: Springer Book Archive

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