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The value of the case—control approach for the evaluation of the risk of upper gastrointestinal bleeding associated with the previous use of non-steroidal anti-inflammatory drugs

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Side-Effects of Anti-Inflammatory Drugs 3

Part of the book series: Inflammation and Drug Therapy Series ((IDTH,volume 5))

Abstract

Several studies have reported an association between upper gastrointestinal bleeding (UGIB) and the previous use of acetylsalicylic acid (ASA) [1–11] or non-steroidal anti-inflammatory drugs (NSAIDs) as a whole [12–14]. However, specific estimates for individual drugs are not available because the lower prevalence of use of each individual NSAID — compared with that of ASA — limits the statistical power of any analytical study designed to quantify individual risks.

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Author information

Authors and Affiliations

  1. Servei de Farmacologia Clínica, CS Vall d’Hebron i Universitat Autònoma de Barcelona, 08035, Barcelona, Spain

    J. R. Laporte, X. Carné, A. Figueras, X. Vidal & J. Juan

Authors
  1. J. R. Laporte
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  2. X. Carné
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  3. A. Figueras
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  4. X. Vidal
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  5. J. Juan
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Editor information

Editors and Affiliations

  1. Department of Biomedical Sciences and Pathology, McMaster University Faculty of Health Sciences, Hamilton, L8N 3Z5, Ontario, Canada

    K. D. Rainsford

  2. Istituto of Farmacologia, Università di Verona, Policlinico Borgo Roma, Verona, 37134, Italy

    G. P. Velo

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© 1992 Springer Science+Business Media Dordrecht

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Laporte, J.R., Carné, X., Figueras, A., Vidal, X., Juan, J. (1992). The value of the case—control approach for the evaluation of the risk of upper gastrointestinal bleeding associated with the previous use of non-steroidal anti-inflammatory drugs. In: Rainsford, K.D., Velo, G.P. (eds) Side-Effects of Anti-Inflammatory Drugs 3. Inflammation and Drug Therapy Series, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2982-4_2

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  • DOI: https://doi.org/10.1007/978-94-011-2982-4_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5325-9

  • Online ISBN: 978-94-011-2982-4

  • eBook Packages: Springer Book Archive

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