Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are drugs widely prescribed throughout the world. In the United States, these drugs were prescribed to 44 million patients in 1984 [1]. The utility of these drugs is, in part, due to the high frequency of gastric intolerance to aspirin. Unfortunately, gastrointestinal (GI) side-effects are also the most frequent adverse reactions to NSAIDs [2]. The GI problems reported vary from mild symptoms, such as indigestion, to serious events, including GI bleeding, peptic ulcer disease, and intestinal perforation.
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© 1992 Springer Science+Business Media Dordrecht
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Carson, J.L., Strom, B.L. (1992). The gastrointestinal toxicity of the non-steroidal anti-inflammatory drugs. In: Rainsford, K.D., Velo, G.P. (eds) Side-Effects of Anti-Inflammatory Drugs 3. Inflammation and Drug Therapy Series, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2982-4_1
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DOI: https://doi.org/10.1007/978-94-011-2982-4_1
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