Summary
Positron emission tomography is a rather new diagnostic modality for noninvasive studies of the heart using positron emitting tracers. Important advantages are the use of physiological substrates that can be labeled with positron tracers, the acquisition of accurate tomographic information, and the potential of quantitative measurements not obtainable with any other technique. Especially disorders in myocardial perfusion and metabolism can be studied in a very early stage of the disease process, which may result in application of more appropriate and earlier therapy. Major limitations are the expenses for the positron camera and, in particular, for a cyclotron. However, a positron tracer like rubidium-82 is generator-produced without the need for a cyclotron and provides accurate measurements of myocardial blood flow. Moreover, when effectively used, routine cardiac positron imaging may be cost-saving on the long run. At present, positron emission tomography has been evolved from a complex research device into routinely applicable clinical equipment. It will provide the basis for a specific therapeutic approach in patients with coronary artery disease, thereby justifying the routine, clinical and economic use of positron emission tomography in cardiology.
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van der Wall, E.E. (1992). Positron emission tomography in cardiology: From research device to clinical tool?. In: Nuclear Cardiology and Cardiac Magnetic Resonance. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2826-1_6
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DOI: https://doi.org/10.1007/978-94-011-2826-1_6
Publisher Name: Springer, Dordrecht
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