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Control of the Pulmonary Circulation

  • B. E. Marshall
  • C. Marshall
  • H. F. Frasch
Part of the Developments in Critical Care Medicine and Anesthesiology book series (DCCA, volume 25)

Abstract

The first essay, in this series of three, discussed the influence of anesthesia on pulmonary gas exchange and the role of ventilation/ perfusion ratios in determining the outcome. Hypoxic pulmonary vasoconstriction was shown to be of critical importance. The second essay introduced a model of the pulmonary circulation that permits analysis of complex interactions to reveal the individual influences. Implicit to both these discussions was the concept that HPV contributes to regulation of ventilation/perfusion ratios \( ({\rm{\dot VA}}/{\rm{\dot QC}}) \) and that \( {\rm{\dot VA}}/{\rm{\dot QC}} \) distribution is an important determinant of steady state pulmonary hemodynamics. The purpose of this discussion is to introduce the beginnings of the resolution of this long standing pulmonary research problem.

Keywords

Pulmonary Artery Pressure Pulmonary Vascular Resistance Carbon Dioxide Tension Hypoxic Pulmonary Vasoconstriction Carbon Dioxide Excretion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Domino K.B., Hlastrala M.P., Eisenstein B.L., et al: Effect of regional alveolar hypoxia on gas exchange in dog. J Appl Physiol 67:730–5, 1989PubMedGoogle Scholar
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Copyright information

© Springer Science+Business Media Dordrecht 1992

Authors and Affiliations

  • B. E. Marshall
  • C. Marshall
  • H. F. Frasch

There are no affiliations available

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