Severe Hypoxia: Insights from Extreme Altitude
Severe tissue hypoxia is frequently a feature of patients in the intensive care setting, and two major experiments during the last ten years have greatly clarified the physiological effects of severe hypoxia in man. They are the 1981 American Medical Research Expedition to Everest (AMREE) (1) and Operation Everest II (OE II) in which eight subjects lived for 40 days in a low pressure chamber in a simulated climb of the mounta in (2). In this brief presentation, I shall summarize some of the most interesting results from both experiments.
KeywordsBlood Lactate Severe Hypoxia Hypoxic Pulmonary Vasoconstriction Pulmonary Capillary Oxygen Dissociation Curve
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