Abstract
The mitral inflow is determined by the pressure difference between the left atrium and ventricle, both during the passive filling in early and mid-diastole and during the active filling at atrial contraction. Changes in left atrial pressure as well as in the diastolic pressure in the left ventricle may alter this pressure difference and change the mitral inflow. In normal subjects the early diastolic filling is mainly influenced by the speed of left ventricular relaxation [1, 2]. In young subjects a faster relaxation results in a higher velocity and shorter duration of the early diastolic filling compared to older subjects, as can be seen in Figure 1, A–C. In the elderly a slower rate of relaxation results in a lower velocity and longer duration of the early filling period, and often a higher velocity of flow at atrial contraction [3].
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Hatle, L. (1993). Clinical application of the analysis of diastolic mitral inflow: differentiation of restriction and constriction. In: Hanrath, P., Uebis, R., Krebs, W. (eds) Cardiovascular Imaging by Ultrasound. Developments in Cardiovascular Medicine, vol 134. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2490-4_1
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DOI: https://doi.org/10.1007/978-94-011-2490-4_1
Publisher Name: Springer, Dordrecht
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