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Studies of cardiac receptors by positron emission tomography

  • Aren van Waarde
  • Paul K. Blanksma
  • Joan G. Meeder
  • Gerben M. Visser
  • Wiek H. van Gilst
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 133)

Abstract

New concepts regarding neurohumoral regulation of cardiac function by myocardial receptors in health and disease have become prominent during the last two decades. Radioligand binding studies have greatly advanced our knowledge of hormone and neurotransmitter binding sites. Changes in the number and/or affinity of cardiac receptors have been assessed by in vitro techniques and shown to be associated with congestive heart failure [1, 2, 3], myocardial ischemia and infarction [4, 5, 6, 7, 8, 9], cardiomyopathy [10,11], hypertension [12,13], chronic drug administration [14, 15, 16, 17] and ageing [18]. In vivo assays may improve our understanding of the time course of diseases and enable better prognosis.

Keywords

Positron Emission Tomography Positron Emission Tomography Study Label Compound Muscarinic Cholinergic Receptor Positron Emission Tomography Camera 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1992

Authors and Affiliations

  • Aren van Waarde
  • Paul K. Blanksma
  • Joan G. Meeder
  • Gerben M. Visser
  • Wiek H. van Gilst

There are no affiliations available

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