Myocardial metabolic imaging with fluorine-18 deoxyglucose

  • Neal G. Uren
  • Paolo G. Camici
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 133)


With the definition of coronary artery anatomy by angiography has come the need to characterize the pathophysiological consequences of coronary artery disease. In order to quantify the functional significance of an epicardial coronary stenosis, measurement of coronary blood flow and blood flow reserve has developed using invasive techniques such as Doppler catheterization [1] and coronary sinus thermodilution [2, 3]. Coronary sinus catheterization may also be used to measure the transmyocardial extraction of metabolic substrates by simultaneous catheterization of an artery and coronary sinus or great cardiac vein [4], However, these invasive methods are limited by their inability to measure coronary blood flow or metabolism in different myocardial regions at the same time or in regions supplied by arteries other than the left anterior descending artery in the case of coronary sinus catheterization. This is an even greater limitation if one takes into account the intrinsic regionality of ischemic heart disease.


Positron Emission Tomography Left Anterior Descend Myocardial Blood Flow Coronary Sinus Coronary Blood Flow 
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Copyright information

© Springer Science+Business Media Dordrecht 1992

Authors and Affiliations

  • Neal G. Uren
  • Paolo G. Camici

There are no affiliations available

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