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Atlas of Liver Pathology pp 93–97Cite as

Alcoholic Liver Disease

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Part of the book series: Current Histopathology ((CUHI,volume 23))

Abstract

For many years it was thought that liver disease in the alcoholic was due primarily to nutritional factors and that alcohol was not a hepatotoxinl. On the basis of animal experiments it was assumed that fatty liver alone could then lead on to fibrosis and eventually to cirrhosis. With the recognition of alcoholic hepatitis as a clinical and pathological entity, this then was regarded as an essential step in the progression to cirrhosis. Support for this view seemed to be provided by experimental studies in alcoholic and non-alcoholic human volunteers2 and in a new animal model in baboons2,3. However, the röle of malnutrition as a cofactor cannot be totally excluded4.

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Authors and Affiliations

  1. Department of Histopathology, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK

    D. G. D. Wight

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© 1993 D. G. D. Wight

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Wight, D.G.D. (1993). Alcoholic Liver Disease. In: Atlas of Liver Pathology. Current Histopathology, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2212-2_13

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  • DOI: https://doi.org/10.1007/978-94-011-2212-2_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4980-1

  • Online ISBN: 978-94-011-2212-2

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