Biosynthesis and metabolism of nicotine and related alkaloids

  • L. P. Bush
  • F. F. Fannin
  • R. L. Chelvarajan
  • H. R. Burton


Alkaloids are extremely important in tobacco (Nicotiana tabacum) leaf because they are a major factor in smoke quality, and provide a physiological stimulus which makes the use of tobacco products pleasurable. Nicotine and other alkaloids in Nicotiana spp. have been ascribed many functions, i.e
  • detoxification products

  • waste products

  • nitrogen reserve

  • regulatory substances for plant growth

  • protection for the plant against insects and other herbivores

and consequently they appear to be important to the evolution of the genus as it is known today. However, as important as Nicotiana alkaloids are in eliciting animal responses from the utilization of tobacco, growth and development of the plant proceed normally in the absence of accumulation of alkaloids.


Nicotinic Acid Quinolinic Acid Nicotinamide Adenine Dinucleotide Total Volatile Nitrogenous Basis Nicotine Level 
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© Springer Science+Business Media Dordrecht 1993

Authors and Affiliations

  • L. P. Bush
  • F. F. Fannin
  • R. L. Chelvarajan
  • H. R. Burton

There are no affiliations available

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