Molecular and Cellular Oranizates on the Electrode Surface for Electronic Control of Their Functions

Abstract

Monolayers of redox enzymes such as glucose oxidase, fructose dehydrogenase and alcohol dehydrogenase are molecularly organized on the electrode surface and are facilitated with electronic communication with the electrode through molecular wire of conducting polymer. The enzyme activity of these molecularly interfaced enzymes are electronically modulated, which provides us with a new design principle of biomolecular electronic devices. Furthermore monolayer of cellular organizates of neurons has been formed on the solid material surface under potential-controlled direction of neurite outgrowth.