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Cardiac Output and Regional Flow in Health and Disease pp 195–211Cite as

Cardiac performance and systemic oxygen transport after cardiopulmonary bypass surgery

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 138))

Abstract

The success of cardiopulmonary bypass (CPB) surgery is limited primarily by the risk for mutiorgan damage, which can occur either during the procedure or in the early postoperative period. Intraoperative sources of organ injury include the extracorporeal circuit [1–3], the period of systemic hypothermia [4], and the cardioplegic arrest [5, 6]. The early postoperative period can lead to multiorgan damage if oxygen deficits sustained during the proced ure are not corrected [7], or when ischemic areas release toxic metabolites that produce widespread reperfusion injury in the major organ systems [8]. Finally, the postoperative period can be a source of organ damage when the rate of oxygen delivery in arterial blood is inadequate to serve the needs of aerobic metabolism [9].

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Authors
  1. Paul L. Marino
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  2. James D. Sink
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Editor information

Editors and Affiliations

  1. Department of Cardiology, Central Middlesex Hospital, London, UK

    Abdul-Majeed Salmasi

  2. Presbyterian Medical Center, Philadelphia Heart Institute, Philadelphia, Pennsylvania, USA

    Abdulmassih S. Iskandrian

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© 1993 Springer Science+Business Media Dordrecht

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Marino, P.L., Sink, J.D. (1993). Cardiac performance and systemic oxygen transport after cardiopulmonary bypass surgery. In: Salmasi, AM., Iskandrian, A.S. (eds) Cardiac Output and Regional Flow in Health and Disease. Developments in Cardiovascular Medicine, vol 138. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1848-4_17

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  • DOI: https://doi.org/10.1007/978-94-011-1848-4_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4816-3

  • Online ISBN: 978-94-011-1848-4

  • eBook Packages: Springer Book Archive

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