Host resistance and immune system
Elderly humans are more susceptible and more vulnerable to many infections than younger adults. For this reason, the elderly may be considered an ‘immunocompromised host’, due to the effect of age itself on the immune system and also to diseases that accompany aging which themselves compromise immune function. It has been shown that antibody response of elderly subjects to influenza immunization are inversely correlated with the severity of their associated illness . Thus, immune senescence contributes to the diseases of aging which in turn, further compromise immune competence.
KeywordsHerpes Zoster Influenza Vaccine Host Resistance Thymic Involution Influenza Immunization
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