Skip to main content
SpringerLink
Log in

Treatment of hypertension in the elderly

  • Chapter
Nephrology and Urology in the Aged Patient

Part of the book series: Developments in Nephrology ((DINE,volume 34))

Abstract

By virtue of sheer numbers, hypertension in the elderly is a major public health problem: prevalence of hypertension is high in this age group, and the elderly segment of the American population is growing rapidly. The confirmed benefit of treatment of hypertension in the elderly, both isolated systolic and diastolic, makes it even more important now than ever to identify and treat such patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Vokonas PS, Kannel WB, Cupples LA. Epidemiology and risk of hypertension in the elderly: the Framingham Study. J Hypertens 1988; 6(Suppl 1):S3–S9.

    CAS  Google Scholar 

  2. Subcommittee on Definition and Prevalence of the 1984 Joint National Committee. Hypertension prevalence and the status of awareness, treatment, and control in the United States. Final report. Hypertension 1985; 7:457–468.

    Google Scholar 

  3. Curb JD, Borhani BO, Schnaper H, Kass E, Entwisle G, Williams W, Berman R. Detection and treatment of hypertension in older individuals. Am J Epidemiol 1985; 121:371–376.

    Article  CAS  PubMed  Google Scholar 

  4. Adamopoulos PN, Chrysanthakapoulis SG, Frohlich ED. Systolic hypertension: Nonhomogeneous diseases. Am J Cardiol 1975; 36:697–701.

    Article  CAS  PubMed  Google Scholar 

  5. Garland C, Barrett-Connor E, Suarez L, Criqui MH. Isolated systolic hypertension and mortality after age 60 years. A prospective population-based study. Am J Epidemiol 1983; 118:365–376.

    CAS  PubMed  Google Scholar 

  6. Rutan GH, Kuller LH, Neaton DJ, Wentworth DN, McDonald RH, Smith WM. Mortality associated with diastolic hypertension and isolated systolic hypertension among men screened for the Multiple Risk Factor Intervention Trial. Circulation 1988; 77:504–514.

    Article  CAS  PubMed  Google Scholar 

  7. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of the Hypertension Detection and Follow-up Program. II. Mortality by race, sex and age. JAMA 1979; 242:2572–2577.

    Article  Google Scholar 

  8. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of the Hypertension Detection and Follow-up Program. III. Reduction in stroke incidence among persons with high blood pressure. JAMA 1982; 247:633–638.

    Article  Google Scholar 

  9. Borhani NO. Results of clinical trials regarding the efficacy of treating hypertension. Clin Geriatric Med 1989; 5:675–690.

    CAS  Google Scholar 

  10. National Heart Foundation of Australia. Treatment of mild hypertension in the elderly. Med J Aust 1981; 2:398–402.

    Google Scholar 

  11. Amery A, Brixko P, Clement D, et al. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly Trial. Lancet 1985; 1:1349–1354.

    Article  CAS  PubMed  Google Scholar 

  12. Amery A, Brixko R, Clement D, et al: Efficacy of antihypertensive drug treatment according to age, sex, blood pressure, and previous cardiovascular disease in patients over the age of 60. Lancet 1986; 2:589–592.

    Article  CAS  PubMed  Google Scholar 

  13. Fletcher A, Amery A, Birkenhager W, Bulpitt C, et al. Risks and benefits in the trial of the European Working Party on High Blood Pressure in the Elderly. J Hypertens 1991; 9:225–230.

    Article  CAS  PubMed  Google Scholar 

  14. Dahlöf B, Lindholm LH, Hansson L, Schersten B, Ekbom T, Wester PO. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 1991; 338:1281–1285.

    Article  PubMed  Google Scholar 

  15. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991; 265:3255–3264.

    Article  Google Scholar 

  16. MRC Working Party. Medical Research Council trial of treatment of hypertension in older adults: principal results. Br Med J 1992; 304:405–412.

    Article  Google Scholar 

  17. Beard K, Bulpitt C, Mascie-Taylor H, O’Malley K, Sever P, Webb S. Management of elderly patients with sustained hypertension. Br Med J 1992; 304:412–416.

    Article  CAS  Google Scholar 

  18. Farnett L, Mulrow CD, Linn WD, Lucey CR, Tuley MR. The J-curve phenomenon and the treatment of hypertension. Is there a point beyond which pressure reduction is dangerous? JAMA 1991; 265:489–495.

    Article  CAS  PubMed  Google Scholar 

  19. Heikenheimo RJ, Haavisto MV, Kaarela RH, Kanto AJ, Koivunen MJ, Rajala SA. Blood pressure in the very old. J Hypertens 1990; 8:361–367.

    Article  Google Scholar 

  20. Staesson J, Bulpitt C, Clement D, DeLeeuw P, Fagard R, Fletcher A, Forette F, Leonetti G, Nissinen A, O’Malley K, Tuomilehto J, Webseter J, Williams BO. Relation between mortality and treated blood pressure in elderly patients with hypertension: report of the European Working party on High Blood Pressure in the Elderly. Br Med J 1989; 298:1552–1556.

    Article  Google Scholar 

  21. Coope J, Warrender TS: Randomised trial of treatment in elderly patients in primary care. B M J 1986; 293:1145–1151.

    Article  CAS  Google Scholar 

  22. Coope J, Warrender TS. Lowering blood pressure (letter). Lancet 1987; 2:1380.

    Article  Google Scholar 

  23. Col N, Fanale JE, Kronholm P. The role of medication noncompliance and adverse drug reactions in hospitalizations of the elderly. Arch Intern Med 1990; 150:841–845.

    Article  CAS  PubMed  Google Scholar 

  24. Curb JD, Borhani NO, Blaszowski T, Fotiu S, Zimbaldi N, on behalf of the HDFP Cooperative Group. Adverse reactions to antihypertensive drugs in the Hypertension Detection and Follow-up Program (HDFP). Circulation 1982; 66:II-328.

    Google Scholar 

  25. Materson BJ, Cushman WC, Goldstein G, Reda DJ, Freis ED, Ramirez EA, Talmers FN, White TJ, Nunn S, Chapman RH, Khatri I, Schnaper H, Thomas JR, Henderson WG, Fye C. Treatment of hypertension in the elderly: I. Blood pressure and clinical changes. Results of a Department of Veterans Affairs cooperative study. Hypertension 1990; 15:348–360.

    Article  CAS  PubMed  Google Scholar 

  26. Goldstein G, Materson BJ, Cushman WC, Reda DJ, Freis ED, Ramirez EA, Talmers FN, White TJ, Nunn S, Chapman RH, Khatri I, Schnaper H, Thomas JR, Henderson WG, Fye C. Treatment of hypertension in the elderly: II. Cognitive and behavioral function. Results of a Department of Veterans Affairs Cooperative Study. Hypertension 1990; 15:361–369.

    Article  CAS  PubMed  Google Scholar 

  27. Applegate WB, Phillips HL, Schnaper H, Shepherd AMM, Schocken D, Luhr JC, Koch GG, Park GD. A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women. Arch Intern Med 1991; 151:1817–1823.

    Article  CAS  PubMed  Google Scholar 

  28. Gurland BJ, Teresi J, Smith WM, Black D, Hughes G, Edlavitch S. Effects of treatment for isolated systolic hypertension on cognitive status and depression in the elderly. J Am Geriatr Soc 1988; 36:1015–1022.

    CAS  PubMed  Google Scholar 

  29. Cushman WC, Khatri I, Materson BJ, Reda DJ, Freis ED, Goldstein G, Ramirez EA, Talmers FN, White TJ, Nunn S, Schnaper H, Thomas JR, Henderson WG, Fye C. Treatment of hypertension in the elderly. III. Response of isolated systolic hypertension to various doses of hydrochlorothiazide: Results of a Department of Veterans Affairs cooperative study. Arch Intern Med 1991; 151:1954–1960.

    Article  CAS  PubMed  Google Scholar 

  30. Jeunmaitre X, Charru A, Chatellier G, Degoulet P, et al. Long-term metabolic effects of spironolactone and thiazides combined with potassium-sparing agents for treatment of essential hypertension. Am J Cardiol 1988; 62:1072–1077.

    Article  Google Scholar 

  31. Working Group on Hypertension in the Elderly. Statement on hypertension in the elderly. JAMA 1986; 256:70.

    Article  Google Scholar 

  32. Bühler FR, Bolli P, Kiowski W, Erne P, Hulthen UL, Block LH. Renin profiling to select antihypertensive baseline drugs. Renin inhibitors for high-renin and calcium entry blockers for low-renin patients. Am J Med 1984; 77(2A):36–42.

    PubMed  Google Scholar 

  33. Blaufox MD, Lee HB, Davis B, Oberman A, Wassertheil-Smoller S, Langford H. Renin predicts diastolic blood pressure response to nonpharmacologic and pharmacologic therapy. JAMA 1992; 267:1221–1225.

    Article  CAS  PubMed  Google Scholar 

Download references

Authors
  1. Ray W. Gifford Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Raymond A. Borazanian
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Toronto, Toronto, Ontario, M5T 2S8, Canada

    Dimitrios G. Oreopoulos M.D., Ph.D., F.R.C.P.C, F.A.C.P. (Professor of Medicine, Director, Peritoneal Dialysis) (Professor of Medicine, Director, Peritoneal Dialysis)

  2. The Toronto Hospital, Toronto, Ontario, M5T 2S8, Canada

    Dimitrios G. Oreopoulos M.D., Ph.D., F.R.C.P.C, F.A.C.P. (Professor of Medicine, Director, Peritoneal Dialysis) (Professor of Medicine, Director, Peritoneal Dialysis)

  3. Department of Medicine, Lenox Hill Hospital, New York, New York, USA

    Michael F. Michelis M.D. (Chief, Nephrology Section, Clinical Associate Professor of Medicine) (Chief, Nephrology Section, Clinical Associate Professor of Medicine)

  4. Cornell University Medical College, New York, New York, 10021, USA

    Michael F. Michelis M.D. (Chief, Nephrology Section, Clinical Associate Professor of Medicine) (Chief, Nephrology Section, Clinical Associate Professor of Medicine)

  5. Urodynamics Unit, Sunnybrook Health Science Centre, Toronto, Ontario, M5N 3M5, Canada

    Sender Herschorn B.Sc., M.D.C.M., F.R.C.S.C. (Chief of Urology, Director, Assistant Professor, Consultant Urologist) (Chief of Urology, Director, Assistant Professor, Consultant Urologist)

  6. Department of Surgery(Urology), University of Toronto, Toronto, Canada

    Sender Herschorn B.Sc., M.D.C.M., F.R.C.S.C. (Chief of Urology, Director, Assistant Professor, Consultant Urologist) (Chief of Urology, Director, Assistant Professor, Consultant Urologist)

  7. Lyndhurst Hospital and Rehabilitation Centre, Toronto, Canada

    Sender Herschorn B.Sc., M.D.C.M., F.R.C.S.C. (Chief of Urology, Director, Assistant Professor, Consultant Urologist) (Chief of Urology, Director, Assistant Professor, Consultant Urologist)

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Gifford, R.W., Borazanian, R.A. (1993). Treatment of hypertension in the elderly. In: Oreopoulos, D.G., Michelis, M.F., Herschorn, S. (eds) Nephrology and Urology in the Aged Patient. Developments in Nephrology, vol 34. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1822-4_17

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-1822-4_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4804-0

  • Online ISBN: 978-94-011-1822-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation