Hypertension in the elderly: pathophysiology of aging of the cardiovascular system

  • Haralambos Gavras
  • Irene Gavras
Part of the Developments in Nephrology book series (DINE, volume 34)


Aging is characterized by anatomical, humoral, biochemical and functional alterations, whose rate of progression may vary, as indicated by the individual variability between biological and chronological age. Moreover, the rate of aging of different systems or functions may vary within the same individual. Nevertheless, both longitudinal cohort studies and cross-sectional population surveys have attempted to define normal standards for specific age groups. Knowledge of these standards for various cardiovascular parameters is a necessary requirement for appropriate decision-making during the diagnosis and management of hypertension and cardiovascular diseases, as well as metabolic and other systemic disorders. This review highlights a number of pathophysiologic changes that occur as part of the normal aging process and are relevant to the treatment of hypertension.


Decrease Heart Rate Hemodynamic Alteration Normal Aging Process Hyaline Degeneration Electromechanical Dissociation 
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© Springer Science+Business Media Dordrecht 1993

Authors and Affiliations

  • Haralambos Gavras
  • Irene Gavras

There are no affiliations available

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