Summary
Intermittent coronary perfusion with the use of global hypothermia is one of the oldest techniques in cardiac surgery to allow the management of congenital defects and acquired coronary, valvular or myocardial diseases. With the introduction and further developments of quite different aspects of cardioplegic myocardial preservation - and this development is not yet finished - the technique of intermittent coronary perfusion was more or less completely replaced by cardioplegic methods.
In our unit, intermittent coronary perfusion was used in combination with total body hypothermia and hemodilution since 1959, and performed especially for coronary revascularisations from 1970 until today. During the past 10 years, more and more cardiac centers reported their results using this simple, effective and safe technique for patients with sole coronary artery disease and coronary revascularisation.
In this chapter we describe the effects of hypothermia, our procedure for hypothermic extracorporeal circulation and the use of intermittent coronary aortic cross-clamping with ischemia and reperfusion, mainly in patients with the need of coronary artery revascularisation.
Whether the newly discussed aspects of warm cardiac surgery will be effective and safe enough need further experimental and clinical investigations for a final judgement.
This contribution is dedicated to
Prof. Dr. Wolfgang Bircks
since 1958 involved in the development and accurate performance of cardiovascular surgery and the establishment of a sufficient and effective care of patients with heart disease of all age groups.
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References
Grosse-Brockhoff F, Schoedel W. Das Bild der akuten Unterkühlung im Tierexperiment. Arch Experim Path and Pharmakol 1943; 241: 417.
Bigelow WG, Lindsay WK, Greenwood WF. Hypothermia. Its possible role in cardiac surgery. Ann Surgery 1950; 132: 849.
Swan H. The current status of hypothermia. Arch Surg 1954; 69: 597.
Thauer R. Ergebnisse experimenteller Kreislaufuntersuchungen bei Hypothermie. Thoraxchir 1956: 4: 522.
Brendel W. Kreislauf in Hypothermic. Verh Dtsch Ges Kreislaufforschung 1957: 33
Zindler M. Künstliche Hypothermie für Herzoperationen mit Kreislaufunterbrechung. Forschungshcricht des Landes Nordrhein-Westfalen. Westdeutscher Verlag: Köln 1961; 996.
Zindler M. Dudziak R. Eunike S et al. Surface hypothermia for heart operations with circulatory arrest. Intern Anesthes Clinics 1965; 3: 733–55.
Zindler M. Dudziak R, Eunike S et al. Erfahrungen bei 1290 künstlichen Hypothermien für Herz-und Gefäßoperationen. Anaesthesist 1966; 15: 69–75.
Derra E. Der Vorhofseptumdefekt und rein operativer Verschluß unter Sicht des Auges in Unterkühlungsanästhesie. Dtsch Med Wschr 1955; 80: 1277–80.
Derra E. The surgical treatment of congenital valvular pulmonary stenosis under direct vision during hypothermia. German Med Monthly 1957: 2: 129–32.
Borst HG. Experimentelle Untersuchungen über die kombinierte Anwendung von extrakorporalem Kreislauf und Hypothermic. II. Zur Frage der adäquaten Perfusion in Hypothermie. Langenbecks Arch Klin Chir 1963: 303: 380–403.
Bretschneider HJ. Überlebenszeit und Wiederbelebungszeit des Herzens bei Normo-und Hypothermic. Verb Dtsch Ges Kreislaufforschung 1964; 30: 11–34.
Arnold G. Lochner W. Die Temperaturabhängigkeit des Sauerstoffverbrauchs stillgclegter künstlich perfundierter Warmblüterherzen zwischen 34° und 4°C Pfltigers Arch Ges Physioi 1965: 284: 169–75.
Hoffmeister HE. Stoffwechseluntersuchungen am menschlichen Herzen bei intermittierender Koronarperfusion. Langenbecks Arch Klin Chir 1967; 319: 336–41.
Bircks W. Pulver. KG. Erfahrungswerte der Tolerabilität und notwendigen Dauer der Koronarischämie in der Kardiochirurgie. Langenbecks Arch Klin Chir 1967: 319: 697.
Schulte HD. Derra E Jr., Herzer JA et al. Ischemic tolerance of the human heart during extracorporeal circulation; Clinical experience. J Cardiovasc Surg 1975; 16: 283–7.
Buckberg GD, Brazier JR, Nelson RL et al. Studies of the effects of hypothermia on regional myocardial blood flow and metabolism during cardio-pulmonary bypass. I. The adequately perfused beating. fibrillation and arrested heart. J Thorac Cardiovasc Surg 1977: 73: 84–7.
Laks H. Barner HB, Strandeven JW et al. Myocardial protection by intermittent perfusion with cardioplegic solution vs. intermittent corollary perfusion with cold blood. J Thorac Cardiovasc Surg 1978: 78: 158–72.
Akins CW. Noncardioplegic myocardial preservation for coronary revascularisation. J Thorac Cardiovasc Surg 1984; 88: 174–81.
Bonchek LI. Burlingame MW. Coronary artery bypass surgery. J Thorac Cardiovasc Surgery 1987: 93: 261–7.
Bonchek LI. Burlingame MW. Vazales BE et al. Applicability of noncardioplegie coronary bypass to high-risk patients. Selection of patients. technique, and clinical experience. J Thorac Cardiovasc Surg 1992: 103: 230–6.
Antunes MJ. Bernardo JE, Oliveira JM et al. Coronary artery bypass surgery with intermittent aortic cross-clamping. Europ J Cardiothorac Surg 1992; 6: 189–94.
Schulte HD, Günter J. Grundlagen und Durchführung der extrakorporalen Zirkulation beim Erwachsenen - Das Düsseldorfer Verfahren. In Preusse CJ, Schulte HD (eds): Extrakorporale Zirkulation - Heute -. Darmstadt: Steinkopff-Verlag 1991; 37–54.
Poche R. Ohm HG. Lichtmikroskopische, histochemische und elektronenmikroskopische Untersuchungen des Herzmuskels corn Menschen nach reduziertem Herzstillstand. Arch Kreislauff 1963: 41: 86.
Speicher CE. Ferrigan, Wolfson SK et al. Cold injury of the myocardium and pericardium in cardiac hypothermia. Surg Gvn Obst 1962; 114: 659–65.
Lynen F. Herzstillstand durch isolierte Organunterktihlung mit Kochsalz-Eisschnee. Med Diss Düsseldorf 1963.
Barner HB, Standeven JW, Jellinek M et al. Topical cardiac hypothermia for myocardial preservation. J Thorac Cardiovasc Surg 1977: 73: 856–67.
Robicsek F. Discussions of Griepp RB. J Thorac Cardiovasc Surg 1973; 66: 731–41.
Lichtenstein SK, Fremes SE. Abel JG et al. Technical aspects of warm heart surgery. J Card Surg 1991; 6: 278–85.
Vineberg AN. Development of an anastomosis between the coronary vessels and a transplanted internal mammary artery Canad med Ass J 1946; 55: 117–21.
Favaloro RG. Saphenous vein graft in the surgical treatment of coronary artery disease. Operative technique. J Thorac Cardiovasc Surg 1968; 58: 178–82.
Bretschneider HJ. Myocardial Protection. Thorac Cardiovasc Surg 1980; 28: 295–302.
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Schulte, H.D. (1993). Intermittent coronary perfusion. In: Piper, H.M., Preusse, C.J. (eds) Ischemia-reperfusion in cardiac surgery. Developments in Cardiovascular Medicine, vol 142. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1713-5_9
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DOI: https://doi.org/10.1007/978-94-011-1713-5_9
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