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Muscle birefringence

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Ischemia-reperfusion in cardiac surgery

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 142))

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Abstract

Quantitative birefringence measurements (QBM) are a valuable means of assessing myocardial protection during open heart surgery because they provide an index of myocardial contractility at a cellular level [1]. Most importantly they can be done on small needle biopsies and can measure changes in myocardial function even when the heart is arrested and conventional hemodynamic assessment is impossible.

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References

  1. Chayen J, Bitensky L, Braimbridge MV et al. Increased myosin orientation during muscle contraction: a measure of cardiac contractility. Cell Biochem Funct 1985; 3: 101–14.

    Article  PubMed  CAS  Google Scholar 

  2. Webb-Peploe MM. Apport de la biopsie myocardique au diagnostic et au traitement des myocardiopathies primitives. Ann Cardiol Angiol 1978; 27: 579–88.

    CAS  Google Scholar 

  3. Malcolm AD, Cankovic-Darracott S, Chayen J et al. Biopsy evidence of left ventricular myocardial abnormality in patients with mitral leaflet prolapse and chest pain. Lancet 1979; 8125: 1052–5.

    Article  Google Scholar 

  4. Cankovic-Darracott S, Braimbridge MV, Williams BT et al. Myocardial preservation during aortic valve surgery. Assessment of 5 techniques by cellular chemical and biophysical methods. J Thorac Cardiovasc Surg 1977; 73: 699–706.

    PubMed  CAS  Google Scholar 

  5. Braimbridge MV, Chayen J, Bitensky L et al. Cold cardioplegia or continuous coronary perfusion? J Thorac Cardiovasc Surg 1977; 74: 900–6.

    PubMed  CAS  Google Scholar 

  6. Cankovic-Darracott S, Braimbridge MV, Bitensky L et al. Evaluation of perfusion conditions in cardiopulmonary bypass. In Kobayashi T, Ito Y, Rona G (eds): Recent advances in studies on cardiac structure and metabolism, Vol 12. Cardiac adaptation. New York: University Park Press 1978; 593–6.

    Google Scholar 

  7. Braimbridge MV, Cankovic-Darracott S. Quantitative polarization microscopy and cytochemistry in assessing myocardial function. In Pattison JR, Bitensky L, Chayen J (eds): Quantitative cytochemistry and its application. London: Academic Press 1979; 221–30.

    Google Scholar 

  8. Darracott-Cankovic S. Methods for assessing preservation techniques - invasive methods (enzymatic, cytochemical). In Engelman RM, Levitsky, L (eds): A handbook of clinical cardioplegia. New York: Futura Publishing Co 1982; 43–61.

    Google Scholar 

  9. Bull C, Cooper J, Stark J. Cardioplegic protection of the child’s heart. J Thorac Cardiovasc Surg 1982; 88: 287–93.

    Google Scholar 

  10. Pepper JR, Lockey E, Cankovic-Darracott S et al. Cardioplegia versus intermittent ischaemic arrest in coronary bypass surgery. Thorax 1982; 37: 887–92.

    Article  PubMed  CAS  Google Scholar 

  11. Chambers DJ, Darracott-Cankovic S, Braimbridge MV. Clinical and quantitative birefringence assessment of 100 patients with aortic clamping periods in excess of 120 minutes of hypothermic cardioplegic arrest. Thorac Cardiovasc Surg 1983; 31: 266–72.

    Article  PubMed  CAS  Google Scholar 

  12. Braimbridge MV, Darracott-Cankovic S, Chambers DJ et al. Biopsy assessment of myocardial protection for valve replacement over the last 24 years. Ann Thorac Surg 1989; 48: 567–8.

    Article  Google Scholar 

  13. Darracott-Cankovic S, Cory-Pearce R, Stovin PGI et al. Biopsy assessment of 50 hearts during transplantation. J Thorac Cardiovasc Surg 1987; 93: 95–102.

    PubMed  CAS  Google Scholar 

  14. Darracott-Cankovic S, Stovin PGI, Wheeldon D et al. Effect of donor heart damage on survival after transplantation. Eur J Cardiothorac Surg 1989; 3: 525–32.

    Article  PubMed  CAS  Google Scholar 

  15. Darracott-Cankovic S, English TAH, Wallwork J. Assessing damage to the donor heart. In D’Alessandro LC (ed): Heart Surgery 1991. Rome: Casa Editrice Scientifica Internazionale 1991; 459–74.

    Google Scholar 

  16. Darracott-Cankovic S. Assessment of myocardial preservation during heart and heart-lung transplantation. Transplant Rev 1992: 6(2): 102–14.

    Article  Google Scholar 

  17. Chiu RC-J. Cardioplegia: from the bedside to the laboratory and back again. Ann Thorac Surg 1991; 52: 1209–10.

    Article  PubMed  CAS  Google Scholar 

  18. Chambers DJ, Kosker S, Takahashi A et al. Comparison of standard (non-oxygenated) vs oxygenated St Thomas’ Hospital cardioplegic solution No. 2 (Plegisol). Eur J Cardiothorac Surg 1990; 4:549–55.

    Article  PubMed  CAS  Google Scholar 

  19. Chambers DJ, Braimbridge MV, Kosker S et al. Creatine phosphate (Neoton) as an additive to St Thomas’ Hospital cardioplegic solution (Plegisol). Eur J Cardio Thorac Surg 1991; 5: 74–81.

    Article  CAS  Google Scholar 

  20. Huxley AF. Muscle structure and theories of contraction. Prog Biophys 1957; 7: 255–310.

    CAS  Google Scholar 

  21. Huxley HE. The mechanism of muscular contraction. Science. 1969; 64: 1356–66.

    Article  Google Scholar 

  22. Hanson J, Huxley HE. Structural basis of the cross-striations in muscle. Nature 1953; 172:530–6.

    Article  PubMed  CAS  Google Scholar 

  23. Hayashi T. Chemical physiology of excitation in muscle and nerve. Tokyo: NakayamaShoten 1956; 92–3.

    Google Scholar 

  24. Huxley HE, Hanson J. Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature 1954; 173: 973–5.

    Article  PubMed  CAS  Google Scholar 

  25. Darracott-Cankovic S. PhD Thesis: Cellular biochemical and biophysical studies of myocar-dial preservation during cardiac surgical procedures. University of London, 1982: 120–258.

    Google Scholar 

  26. Kolettis M, Jenkins BS, Webb-Peploe MM. Assessment of left ventricular function by indices derived from aortic flow velocity. Br Heart J 1976; 38: 18–31.

    Article  PubMed  CAS  Google Scholar 

  27. Hearse DJ, Stewart DA, Braimbridge MV. Hypothermic arrest and potassium arrest;metabolic and myocardial protection during elective cardiac arrest. Circ Res 1975; 36: 4819.

    Article  Google Scholar 

  28. Jynge P, Hearse DJ, Feuvray D et al. The St Thomas’ Hospital cardioplegic solution: a characterization in two species. Scand J Thorac Cardiovasc Surg 1981; 30: 1–28.

    CAS  Google Scholar 

  29. Hearse DJ, Braimbridge MV, Jynge P. Components of cardioplegic solutions. In: Protection of the ischemic myocardium. New York: Raven Press, 1981; 209–99.

    Google Scholar 

  30. Yamamoto F, Braimbridge MV, Hearse DJ. Calcium and cardioplegia. J Thorac Cardiovasc Surg 1984; 87: 908–12.

    PubMed  CAS  Google Scholar 

  31. Robinson LA. Braimbridge MV, Hearse DJ. The potential hazard of particulate contamination of cardioplegic solutions. J Thorac Cardiovasc Surg. 1984; 87: 48–58.

    PubMed  CAS  Google Scholar 

  32. Hearse DJ, Erol C. Robinson LA et al. Particle-induced coronary vasoconstriction during cardioplegic infusion. Characterization and possible mechanisms. J Thorac Cardiovasc Surg 1985; 89: 428–38.

    PubMed  CAS  Google Scholar 

  33. Chambers DJ, Sakai A, Braimbridge MV et al. Clinical validation of St Thomas Hospital cardioplegic solution No. 2 (Plegisol). Eur J Cardio-thorac Surg 1989; 3: 346–52.

    Article  CAS  Google Scholar 

  34. Bleese N, Miring V, Kalmar P et al. Clinical application of cardioplegia in aortic cross-clamping periods longer than 150 minutes. Thorac Cardiovasc Surgeon 1979; 27: 390–2.

    Article  CAS  Google Scholar 

  35. Engelman RM, Rousou JH, Vertrees RA et al. Safety of prolonged ischemic arrest using hypothermic cardioplegia. J Thorac Cardiovasc. Surg 1980; 79: 705–12.

    PubMed  CAS  Google Scholar 

  36. Engelman RM, Gianelly RE, Rousou JH et al. The effect of prolonged cardioplegic arrest on long-term ventricular function. Thorac Cardiovasc Surgeon 1981; 29: 223–6.

    Article  CAS  Google Scholar 

  37. Stapenhorst K. Prolonged safe ischemic cardiac arrest using hypothermic Bretschneider cardioplegia combined with topical cardiac cooling. Thorac Cardiovasc Surgeon 1981; 29: 272–4.

    Article  CAS  Google Scholar 

  38. Berglin E, Feddersen K, Gatzinsky P et al. Aortic cross-clamping for more than 2 hours in open-heart surgery. Early results in 87 patients. Thorac Cardiovasc Surgeon 1983; 31: 2736.

    Google Scholar 

  39. Braimbridge MV, Darracott-Cankovic S. Assessment of right ventricular preservation during cold cardioplegic arrest. In Birks W, Ostermeyer J, Schulte HD (eds): Cardiovascular surgery. Berlin: Springer Verlag 1980; 625–8.

    Google Scholar 

  40. Hetzer R, Warnecke H, Wittock H et al. Extracoronary collateral myocardial blood flow during cardioplegic arrest. J Cardiovasc Surg 1980; 28: 191–6.

    CAS  Google Scholar 

  41. Braimbridge MV. Myocardial protection. In Taylor KM (ed): Cardiopulmonary bypass-principle and management. London: Chapman and Hall 1986; 375–98.

    Google Scholar 

  42. Smith PK, Buhrman WC, Levett JM et al.. Supraventricular conduction abnormalities following cardiac operations: a complication of inadequate atrial preservation. J Thorac Cardiovasc Surg 1983; 85: 105–15.

    PubMed  CAS  Google Scholar 

  43. Weisel RD. Intraoperative atrial protection. Can J Cardiol 1986; 2: 261–2.

    PubMed  CAS  Google Scholar 

  44. Rosenfeldt FL, Watson DA. Interference with local myocardial cooling by heat gain during aortic cross-clamping. Ann Thorac Surg 1979; 27: 13–6.

    Article  PubMed  CAS  Google Scholar 

  45. Fisk RL, Ghaswalla D, Guillbeau EJ. Asymmetrical myocardial hypothermia during hypothermic cardioplegia. Ann Thorac Surg 1982; 34: 318–23.

    Article  PubMed  CAS  Google Scholar 

  46. Chiu RC-J, Mulder DS. Complications of cardioplegic preservation. In Engelman RM, Levitsky L (eds): A handbook of clinical cardioplegia. New York: Futura Publishing Co 1982; 391–403.

    Google Scholar 

  47. Bonchek LI, Olinger GN. An improved method of topical hypothermia. J Thorac Cardiovasc Surg 1981; 82: 878–82.

    PubMed  CAS  Google Scholar 

  48. Velardi AR, Widmer SJ, Cilley JH et al. Right ventricular myocardial protection through intracavitary cooling in cardiac operations. J Thorac Cardiovasc Surg 1989; 98: 1077–82.

    PubMed  CAS  Google Scholar 

  49. Douville EC, Kratz JM, Spinale FG et al. Retrograde versus antegrade cardioplegia: impact on right ventricular function. Ann Thorac Surg 1992; 54: 56–61.

    Article  PubMed  CAS  Google Scholar 

  50. Chen YE, Lin YT, Wu SC. Inconsistent effectiveness of myocardial preservation among cardiac chambers during hypothermic cardioplegia. J Thorac Cardiovasc Surg 1991; 102: 684–7.

    PubMed  CAS  Google Scholar 

  51. Teoh KH, Mullen JC, Weisel RD et al. Right and left ventricular metabolites. J Thorac Cardiovasc Surg 1988: 96: 725–9.

    PubMed  CAS  Google Scholar 

  52. Christakis GT, Weisel RD, Mickle DAG et al. Right ventricular function and metabolism. Circulation 1990; 82: IV332–40.

    PubMed  CAS  Google Scholar 

  53. Hilton CJ, Teubl W, Acker M et al. Inadequate cardioplegic protection with obstructed coronary arteries. Ann Thorac Surg 1979; 28: 323–34.

    Article  PubMed  CAS  Google Scholar 

  54. Landymore RW, Tice D, Trehan N et al. Importance of topical hypothermia to ensure uniform myocardial cooling during coronary artery bypass. J Thorac Cardiovasc Surg 1981; 82: 832–6.

    PubMed  CAS  Google Scholar 

  55. Daggett WM, Jacocks MA, Coleman WS et al. Myocardial temperature mapping. J Thorac Cardiovasc Surg 1981; 82: 883–8.

    PubMed  CAS  Google Scholar 

  56. Robertson JM, Buckberg GD, Vinten-Johansen J et al. Comparison of distribution beyond coronary stenoses of blood and asanguineous cardioplegic solutions. J Thorac Cardiovasc Surg 1983; 86: 80–6.

    PubMed  CAS  Google Scholar 

  57. Naylor WG. Protection of the myocardium against post ischemic reperfusion damage. The combined effect of hypothermia and Nifedipine. J Thorac Cardiovasc Surg 1982; 84: 897905.

    Google Scholar 

  58. Vanden Baviere HFA, Cankovic-Darracott S, De Rose J et al. Enhancement of cardio protective activity during myocardial ischemia using Nifedipine as an additive to crystallod cardioplegia. J Cardiovasc Surg 1983; 24: 407.

    Google Scholar 

  59. Clark RE, Magovern GJ, Christlieb IY et al. Nifedipine cardioplegia experience: results of a 3 year cooperative clinical study. Ann Thorac Surg 1983; 36: 654.

    Article  PubMed  CAS  Google Scholar 

  60. Yamamoto F, Manning AS, Braimbridge MV et al. Nifedipine and cardioplegia: rat heart studies with the St Thomas’ Hospital cardioplegic solution. Cardiovasc Res 1983; 17: 719–27.

    Article  PubMed  CAS  Google Scholar 

  61. Silverman NA, Kohler J, Levitsky S et al. Chronic hypoxemia depresses global ventricular function during cardioplegic arrest: implications for surgical repair of cyanotic congenital heart defects. Ann Thorac Surg 1984; 37: 304–8.

    Article  PubMed  CAS  Google Scholar 

  62. Fujiwara T, Kurtts T, Anderson W et al. Myocardial protection in cyanotic neonatal lambs. J Thorac Cardiovasc Surg 1988; 96: 700–10.

    PubMed  CAS  Google Scholar 

  63. Del Nido PJ, Mickle DA, Wilson GJ et al. Inadequate myocardial protection with cold cardioplegic arrest during repair of tetralogy of Fallot. J Thorac Cardiovasc Surg 1988; 95: 223–9.

    PubMed  Google Scholar 

  64. Kaye MP. The Registry of the International Society for Heart and Lung Transplantation: Ninth official report - 1992. J Heart Lung Transplant 1992; 11: 599–618.

    Google Scholar 

  65. Kriett JM, Kaye MP. The Registry of the International Society for Heart Transplantation: Seventh official report - 1990. J Heart Transplant 1990; 9: 323–30.

    PubMed  CAS  Google Scholar 

  66. Smith RP, Tomlinson BE. Subendocardial haemorrhages associated with intracranial lesions. J Path Bact 1954; 68: 327–9.

    Article  PubMed  CAS  Google Scholar 

  67. De Pasquale NP, Burch GE. How normal is the donor heart? Am Heart J 1969; 77: 719–20.

    Article  Google Scholar 

  68. Samuels MA. Neurogenic heart disease: A unifying hypothesis. Am J Cardiol 1987; 60: 15J–19J.

    Article  PubMed  CAS  Google Scholar 

  69. Novitzky D, Wicomb WN, Cooper DKC et al. Electrocardiographic, haemodynamic and endocrine changes occurring during experimental brain death in the Chacma baboon. Heart Transplant 1984; 4: 63–9.

    Google Scholar 

  70. Wicomb WN, Cooper DKC, Lanza RP et al. The effects of brain death and 24 hours storage by hypothermic perfusion on donor heart function in the pig. J Thorac Cardiovasc Surg 1986; 91: 896–909.

    PubMed  CAS  Google Scholar 

  71. Novitzky D, Wicomb WN, Cooper DKC et al. Improved cardiac function following hormonal therapy in brain dead pigs: relevance to organ donation. Cryobiology 1987; 24: 110.

    Article  Google Scholar 

  72. Novitzky D, Cooper DKC, Morrell D et al. Change from aerobic to anaerobic metabolism after brain death, and reversal following triiodothyronin therapy. Transplantation 1988; 45(1): 32–6.

    Article  PubMed  CAS  Google Scholar 

  73. Novitzky D, Cooper DKC, Reichart B. Haemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation 1987; 43: 852–4.

    PubMed  CAS  Google Scholar 

  74. Hakim M, Higenbottam T, Bethune D et al. Selection and procurement of combined heart and lung grafts for transplantation. J Thorac Cardiovasc Surg 1988; 95: 474–9.

    PubMed  CAS  Google Scholar 

  75. Ghosh S, Bethune DW, Hardy I et al. Management of donors for heart and heart-lung transplantation. Anaesthesia 1990: 45: 672–5.

    Article  PubMed  CAS  Google Scholar 

  76. Buckberg GD. Phases of myocardial protection during transplantation. J Thorac Cardiovase Surg 1990, 100: 461–2.

    CAS  Google Scholar 

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Authors
  1. Sally Darracott-Cankovic
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Editors and Affiliations

  1. Institute of Physiology, Heinrich-Heine-University, Düsseldorf, Germany

    Hans Michael Piper

  2. Department of Thoracic and Cardiovascular Surgery, Heinrich-Heine-University, Düsseldorf, Germany

    Claus J. Preusse

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© 1993 Springer Science+Business Media Dordrecht

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Darracott-Cankovic, S. (1993). Muscle birefringence. In: Piper, H.M., Preusse, C.J. (eds) Ischemia-reperfusion in cardiac surgery. Developments in Cardiovascular Medicine, vol 142. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1713-5_17

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  • DOI: https://doi.org/10.1007/978-94-011-1713-5_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4750-0

  • Online ISBN: 978-94-011-1713-5

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