Abstract
Although an increase in the number of LDL particles, as seen in familial hypercholesterolemia or hyperapobetalipoproteinemia, is strongly associated with the development of CAD (1,2), elevations of triglyceride-rich lipoproteins (TRL) have not been established clearly as — cardiovascular risk factor in prospective studies. However, in case-control studies, triglycerides are often, on univariate analysis, — risk factor for the presence of CAD (3). The heterogeneity within TRL and the different metabolic fates of the various TRL particles may, in part, explain those findings.
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Fruchart, J.C. (1993). Lipoprotein Particles Heterogeneity: Clinical and Pharmacological Implication. In: Catapano, A.L., Gotto, A.M., Smith, L.C., Paoletti, R. (eds) Drugs Affecting Lipid Metabolism. Medical Science Symposia Series, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1703-6_46
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DOI: https://doi.org/10.1007/978-94-011-1703-6_46
Publisher Name: Springer, Dordrecht
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