Abstract
The indirect immunofluorescence assay (IFA) is the most commonly used technique for the detection of antinuclear antibodies (ANA)[1]. It is a sensitive, reproducible and simple assay that can be performed in almost every laboratory. Because IFA enables the detection of a wide range of autoantibodies, it is generally used as a primary screening test for ANA [2].
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Abbreviations
- ANA:
-
antinuclear antibodies
- CIE:
-
counter-immunoelectrophoresis
- hnRNP:
-
heterogeneous nuclear RNP
- IFA:
-
indirect immunofluorescence assay
- JCA:
-
juvenile chronic arthritis
- RA:
-
rheumatoid arthritis
- RNP:
-
ribonucleoprotein
- SLE:
-
systemic lupus erythematosus
- snRNP:
-
small nuclear RNP
- SS:
-
Sjögren’s syndrome
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© 1996 Kluwer Academic Publishers
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Humbel, R.L. (1996). Detection of antinuclear antibodies by immunofluorescence. In: van Venrooij, W.J., Maini, R.N. (eds) Manual of Biological Markers of Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1670-1_2
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DOI: https://doi.org/10.1007/978-94-011-1670-1_2
Publisher Name: Springer, Dordrecht
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