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Lp(a) Lipoprotein: A Monogenic Risk Factor for Cardiovascular Disease

  • Chapter
Genetic factors in coronary heart disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 156))

Abstract

The Lp(a) lipoprotein1 is a distinct class of serum lipoprotein particles which was detected because of its immunological properties. It consists of a low density lipoprotein (LDL) particle to which a long polypeptide chain has been attached (the Lp(a) polypeptide chain, the Lp(a) apolipoprotein or apolipoprotein(a)). It is the Lp(a) polypeptide chain that confers the unique antigenic properties to the Lp(a) lipoprotein particle.

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Authors and Affiliations

  1. Institute of Medical Genetics, University of Oslo and Ullevål University Hospital, P.O. Box 1036, Blindem, N-0135, Oslo 3, Norway

    Kåre Berg

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  1. Kåre Berg
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Editors and Affiliations

  1. Sackler Medical Faculty, Epidemiology and Biostatistics, the Neufeld Cardiac Research Institute, Sheba Medical Center and Tel Aviv University, Israel

    Uri Goldbourt (Professor of Epidemiology and Preventive Medicine, Head) (Professor of Epidemiology and Preventive Medicine, Head)

  2. Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institute and Division of Cardiovascular Medicine, Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden

    Ulf de Faire (Professor) (Professor)

  3. Institute of Medical Genetics, Department of Medical Genetics, Ullevål University Hospital, Oslo, Norway

    Kåre Berg (Professor of Medicine, Chairman, Director and Physician-in-Chief) (Professor of Medicine, Chairman, Director and Physician-in-Chief)

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Berg, K. (1994). Lp(a) Lipoprotein: A Monogenic Risk Factor for Cardiovascular Disease. In: Goldbourt, U., de Faire, U., Berg, K. (eds) Genetic factors in coronary heart disease. Developments in Cardiovascular Medicine, vol 156. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1130-0_18

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  • DOI: https://doi.org/10.1007/978-94-011-1130-0_18

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  • Print ISBN: 978-94-010-4494-3

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